CAS: 7424-91-1; Methyl 3,3-Dimethoxypropanoate

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上下游产品

CAS号67-56-1 甲醇 | CAS号292638-85-8 丙烯酸甲酯 | CAS号922-67-8 甲基丙烯酸酯 | CAS号167386-80-3 trimethyl trans... | CAS号149-73-5 原甲酸三甲酯 | CAS号116140-91-1 1,1,1-Trichloro... | CAS号34846-90-7 3-甲氧基丙烯酸甲酯 | CAS号124-41-4 甲醇钠 | CAS号1865-13-0 methyl 3-(benze... | CAS号5788-17-0 3-甲氧基丙烯酸甲酯 | CAS号308348-93-8 2-氨基吡啶-5-羧酸甲酯 | CAS号34846-90-7 3-甲氧基丙烯酸甲酯 | CAS号21320-99-0 4(1H)-Pyrimidin... | CAS号35351-35-0 5-甲基-3-呋喃甲酸甲酯 | CAS号66-22-8 尿嘧啶 | CAS号80370-42-9 2-甲酰基-3-氧代丙酸乙酯 | CAS号101080-71-1 1-(4-chlorophen... | CAS号141-90-2 2-硫脲嘧啶 | CAS号172595-68-5 5-甲氧基-1H-吲哚-3-甲酸甲酯

3-(Acetyl-Isopropyl-Amino)-3-Methoxy-Propionic Acid Methyl Ester置于对甲苯磺酸体系中,用 甲醇 作为反应溶剂,化学反应 2.5H,以90%的收率获得产物3,3-二甲氧基丙酸甲酯
参考文献:A Practical Access To Methyl 3,3-Dimethoxypropionates And N-Protected .Beta.-Aminoacrylates And .Beta.-Aminoacrylonitrile By Using Electrochemical Procedure
标题:A Practical Access To Methyl 3,3-Dimethoxypropionates And N-Protected .Beta.-Aminoacrylates And .Beta.-Aminoacrylonitrile By Using Electrochemical Procedure
摘要:
DOI:10.1021/jo00221A038

专利信息

专利号:US-10494372-B2
优先权日:2014-11-07
标 题 :Synthesis of copanlisib and its dihydrochloride salt
发明人：PETERS JAN-GEORG; RUBENBAUER PHILIPP; GÖTZ DANIEL; GROSSBACH DANJA; MAIS FRANZ-JOSEF; SCHIRMER HEIKO; STIEHL JUERGEN; LOVIS KAI; LENDER ANDREAS; SEYFRIED MARTIN; ZWEIFEL THEODOR; MARTY MAURUS; WEINGÄRTNER GÃœNTER
权利人:Bayer Pharma AG
摘要:The present invention relates to a novel method of preparing copanlisib, copanlisib dihydrochloride, or hydrates of copanlisib dihydrochloride, to novel intermediate compounds, and to the use of said novel intermediate compounds for the preparation of said copanlisib, copanlisib dihydrochloride, or hydrates of copanlisib dihydrochloride. The present invention also relates to copanlisib dihydrochloride hydrates as compounds.

专利号:US-9493461-B2
优先权日:2013-02-07
标 题 :Tetracyclic heterocycle compounds and methods of use thereof for the treatment of hepatitis C
发明人：DAI XING; LIU HONG; PALANI ANANDAN; HE SHUWEN; LAI ZHONG; NARGUND RAVI; MARCANTONIO KAREN; XIAO DONG; BROCKUNIER LINDA L; ZORN NICOLAS; DANG QUN; PENG XUANJIA; LI PENG
权利人:MERCK SHARP & DOHME
摘要:The present invention relates to compounds of formula I that are useful as hepatitis C virus (HCV) NS5B polymerase inhibitors, the synthesis of such compounds, and the use of such compounds for inhibiting HCV NS5B polymerase activity, for treating or preventing HCV infections and for inhibiting HCV viral replication and/or viral production in a cell-based system.

专利号:US-10035803-B2
优先权日:2014-11-07
标 题:Synthesis of copanlisib and its dihydrochloride salt
发明人：PETERS JAN-GEORG; STIEHL JÃœRGEN; LOVIS KAI
权利人:Bayer Pharma AG
摘要:The present invention relates to a novel method of preparing copanlisib, and copanlisib dihydrochloride, to novel intermediate compounds, and to the use of said novel intermediate compounds for the preparation of said copanlisib.

专利号:US-7205300-B2
优先权日:1997-12-31
标 题:Aryl fused azapolycyclic compounds
发明人：COE JOTHAM WADSWORTH; BROOKS PAIGE ROANNE PALMER
权利人:PFIZER
摘要:This invention is directed to compounds of the formula (I): n nand their pharmaceutically acceptable salts, wherein R 1 , R 2 , and R 3 are as defined herein; intermediates for the synthesis of such compounds, pharmaceutical compositions containing such compounds; and methods of using such compounds in the treatment of neurological and psychological disorders.

专利号:TW-I697494-B
优先权日:2014-11-07
标 题:Synthesis of copanlisib and its dihydrochloride salt

专利号:EA-035558-B1
优先权日:2014-11-07
标题 :SYNTHESIS OF COPANLISIB AND ITS DIHYDROCHLORIDE