CAS: 40150-92-3; A-(4-Isobutylphenyl)Ethanol

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CAS号38861-78-8 4-异丁基苯乙酮 | CAS号538-93-2 异丁基苯 | CAS号15687-27-1 布洛芬 | CAS号51407-46-6 2-(4-异丁基苯基)丙醛 | CAS号38861-78-8 4-异丁基苯乙酮 | CAS号133868-69-6 (S)-(-)-2-(4-is... | CAS号51146-56-6 (S)-(+)-布洛芬 | CAS号51146-57-7 (R)-布洛芬 | CAS号15687-27-1 布洛芬 | CAS号65322-85-2 3-(4-异丁基苯基)丙酸 | CAS号63444-56-4 对异丁基苯乙烯

📜异丁基苯置于aluminum (Iii) Chloride,Sodium Tetrahydroborate体系中,用 甲醇,二氯甲烷 作为反应溶剂,化学反应 2.5H,反应生成 Alpha-甲基-4-(2-甲基丙基)-苯甲醇
参考文献:硅纳米线作为二氧化碳固定光电极
标题:硅纳米线作为二氧化碳固定光电极
摘要:灯亮:当被照亮时,P 型硅纳米线将光生电子提供给芳香酮,产生可以收集 Co 2以产生α-羟基酸的反应性自由基(参见方案).该反应方案与自然光合作用非常相似,产率和选择性高达 98%.通过该反应获得的产品包括非甾体抗炎药的重要前体,如布洛芬和萘普生.
DOI:10.1002/anie.201202569

专利信息

专利号:US-5248815-A
优先权日:1991-12-27
标 题 :Stereo-selective synthesis of 2-aryl-propionic acids of high optical purity by using chiral oxazolines
发明人：PARADIES HENRICH H
权利人:PARADIES HENRICH H
摘要:The present invention relates to a stereospecific chemical synthesis of optically pure enantiomers of 2-aryl-alkanoic acids, especially those of the biologically active (S)-aryl-propionic acids, in good chemical yields, useful for preparing large quantities thereof, and having a high optical purity.

专利号:US-11639326-B2
优先权日:2017-04-06
标 题 :Continuous flow synthesis of ibuprofen
发明人：COLLINS NATHAN; MALERICH JEREMIAH; SZETO JUDY; KOZOCAS JOSEPH A
权利人:STANFORD RES INST INT
摘要:This disclosure generally relates to methods of making ibuprofen, naproxen, and derivatives thereof. This disclosure also generally relates to compounds made by the disclosed methods. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention.

专利号:US-5055611-A
优先权日:1990-12-04
标题 :Process for recycling and regenerating carbonylation catalyst used in synthesis of ibuprofen
发明人：LIN RONNY W; HERNDON JR R CARL; ATKINSON JR E E
权利人:ETHYL CORP
摘要:A process for preparing ibuprofen is described. The improved process involves the treatment of spent palladium carbonylation catalyst with oxygen at about 300° C. to about 850° C. The treated material then used with a phosphine ligand to carbonylate 1-halo-1-(4-isobutyl-phenyl)ethane, 1-hydroxyl-1-(4-isobutylphenyl)ethane, or isobutylstyrene to produce ibuprofen.

专利号:WO-2007044270-A1
优先权日:2005-10-06
标 题:Process for producing high purity ketones by friedel-crafts acylation at low temperature
发明人：MANIMARAN THANIKAVELU; HARKINS ALVIN E
权利人:ALBEMARLE CORP; MANIMARAN THANIKAVELU; HARKINS ALVIN E
摘要:The present invention relates to improved conditions for the Friedel-Crafts acylation of alkylbenzenes and to application of these improved conditions to the synthesis of para-isobutyl acetophenone and ibuprofen. The reaction conditions include operating the reaction at a temperature below 0°C and typically below -10° C.

专利号:US-2021114962-A1
优先权日:2017-04-06
标题 :Continuous flow synthesis of ibuprofen

专利号:EP-0641304-A4
优先权日:1991-12-27
标题:STEREOSPECIFIC SYNTHESIS OF 2-ARYL-PROPIONIC ACIDS OF HIGH OPTICAL PURITY USING CHIRAL OXAZOLINES.