CAS: 3581-91-7; 4,5-Dimethylthiazole

上下游产品

H-thiazole-2-thione4,5-dimethyl-3H-thiazole-2-thione 4,5-dimethylthiazole-2-carboxylic acid 4,5-dimethyl-oxazole 2-hydrazino-4,5-dimethyl-thiazole; hydr°Chloride 1-(4,5-dimethylthiazol-2-yl)ethanone 2-benzyl-4,5-dimethyl-thiazole (4,5-dimethylthiazol-2-yl)(phenyl)methanone (4,5-dimethyl-1,3-thiazol-2-yl)methanol

4,5-Dimethyl-2,5-Dihydro-Thiazole置于sulfur体系中,化学反应生成 4,5-二甲基噻唑
参考文献:Asinger,F. Et Al.,Justus Liebigs Annalen Der Chemie,1961,Vol. 648,P. 83-95
标题:Asinger,F. Et Al.,Justus Liebigs Annalen Der Chemie,1961,Vol. 648,P. 83-95

专利信息

专利号:US-9475814-B2
优先权日:2011-10-03
标题:Chiral N-acyl-5,6,7(8-substituted)-tetrahydro-[1,2,4]triazolo[4,3-a]pyrazines as selective NK-3 receptor antagonists, pharmaceutical composition, methods for use in NK-3 receptor mediated disorders and chiral synthesis thereof
发明人：HOVEYDA HAMID R; DUTHEUIL GUILLAUME; FRASER GRAEME L; ROY MARIE-ODILE; EL BOUSMAQUI MOHAMED; BATT FREDERIC
权利人:EUROSCREEN SA
摘要:The present invention relates to novel compounds of Formula I and their use in therapeutic treatments. The invention further relates to a novel chiral synthesis of 5,6,7,(8-substituted)-tetrahydro-[1,2,4]triazolo[4,3-a]pyrazines using N-sp3 protective groups. The invention also provides intermediates for use in the synthesis of compounds of Formula I.

专利号:US-RE29669-E
优先权日:1973-04-23
标 题:Production of 4-hydroxy-1,2-benzothiazine-3-carboxamides
摘要:A process for the synthesis of N-aryl-3,4-dihydro-2-alkyl-4-oxo-2H-1,2-benzothiazine-3-carboxamide 1,1-dioxides by treatment of N-aryl-N'-alkyl-N'-(2'-alkoxycarbonylbenzenesulfonyl)glycineamides, useful intermediates for said process, with an alkali or alkaline earth metal hydride in a reaction-inert solvent at 50°-150° C., said products being antiinflammatory agents.

专利号:US-5215997-A
优先权日:1985-09-11
标题:Synthesis of beta-lactam compounds
发明人：HUNGERBUEHLER ERNST; KALVODA JAROSLAV
权利人:CIBA GEIGY CORP
摘要:The invention relates to an improved process for the preparation of compounds of formula ##STR1## or salts thereof, starting from compounds of formulae ##STR2## via compounds of formulae ##STR3## in which compounds R 1 is hydrogen or lower alkyl, R 2 is an organic radical which may carry a functional group which may be protected by a customary protective group R 2 o , R 3 is hydrogen or a customary carboxyl protective group R 3 o , W is a group which can be replaced by a thiocarboxylic acid radical of formula III, and Z is oxygen or sulfur.

专利号:US-3943142-A
优先权日:1969-01-24
标 题:Dye intermediates and their preparation and use in the synthesis of methine dyes
发明人：OWEN JOHN R
权利人:EASTMAN KODAK CO
摘要:Compositions of matter are provided comprising a stable, non-vaporous monomeric methylene base selected from a 2-methylenethiazoline; a 2-methylenebenzothiazoline; a 2-methylenenaphthothiazoline; a 2-methylenebenzoselenazoline; and a 2-methylenenaphthoselenazoline. The compositions of the invention are prepared by reacting the parent 2-methyl quaternary salt with a non-hydroxylic base which removes a proton of the heterocyclic salt together with a proton acceptor which inhibits build-up of the hydro salt of the non-hydroxylic base, the reaction being conducted under anhydrous conditions in a non-hydroxylic liquid in which the heterocyclic quaternary salt is sufficiently insoluble to inhibit dimer formation. The compositions of the invention are employed in the preparation of methine dyes.

专利号:US-3558614-A
优先权日:1967-09-05
标题:Synthesis of tetranuclear dyes
发明人：JENKINS PHILIP W
权利人:EASTMAN KODAK CO
摘要:TETRANUCLEAR DYES DERIVED FROM A 2-IMIDAZOLIN-4-ONE, A 2-IMIDAZOLIN-4-THIONE AND A 2-IMIDAZOLIN-4-SELENONE ARE PREPARED IN GOOD YIELDS BY CONDENSING A QUATERNIZED MEROCYANINE DYE DERIVED FROM A 2-IMIDAZOLIN-4-ONE, A 2-IMIDAZOLIN-4-THIONE OR A 2-IMIDAZOLIN4-SELENONE WITH (1) A DIALKOXYALKYL ESTER OF AN ORGANIC ACID, (2) A TRIALKOXY ALKANE OR ARYL COMPOUND, (3) A 3,3-DIALKOZY-1ALKOXYPROPENE, (4) A 1-ANILINO-5-PHENYLIMINO-1,3-PENTADIENE OR (5) A SECOND QUATERNIZED MROCYANINE DYE DERIVED FROM A 2-IMIDAZOLIN-4-ONE, A 2-IMIDAZOLIN-4THIONE OR A 2-IMIDAZOLIN-4-SELENONE, EACH HAVING SUBSTITUTED ON THE CARBON IN THE 2-POSITION A GROUP SUCH AS A B-ACETANILIDOVINYL GROUP, A 4-ACETANILIDO-1,3-BUTADIENYL GROUP, AND A 6-ACETANILIDO-1,3,5-HEXADIENYL GROUP.

专利号:US-6506902-B2
优先权日:2000-03-29
标题:Synthesis of thiazolium compounds
发明人：WAGLE DILIP
权利人:ALTEON INC
摘要:Provided is a method of synthesizing a compound of formula I, n comprising: n (a) reacting a compound of formula II n wherein R 1 and R 2 are independently hydrogen, hydroxy(C 1 -C 2 )alkyl, or (C 1 -C 2 )alkyl with, n a compound of formula III n wherein n R 3 , R 4 , and R 5 are each independently of each other hydrogen, (C 1 -C 3 )alkyl, (C 1 -C 3 )alkoxy, or halogen; and n X is a leaving group, n in a solvent having a dielectric constant at 20° C. of at least 30 but no more than 40; and n (b) obtaining the compound I.