CAS: 301836-41-9; 4-(4-(Benzo[d][1,3]Dioxol-5-yl)-5-(Pyridin-2-yl)-1H-Imidazol-2-yl)Benzamide

上下游产品

4-(4-(Benzo[d][1,3]Dioxol-5-yl)-5-(Pyridin-2-yl)-1H-Imidazol-2-yl)Benzoic Acid 301836-35-1

📜4-[4-(3,4-Methylenedioxyphenyl)-5-(2-Pyridyl)-1H-Imidazol-2-Yl]Benzoyl Chloride Hydrochloride置于ammonium Hydroxide体系中,用 四氢呋喃 作为反应溶剂,以48%的收率获得产物4-[4-(1,3-苯并二唑-5-基)-5-(2-吡啶基)-1H-咪唑-2-基]-苯酰胺水合物
参考文献:Triarylimidazoles
标题:Triarylimidazoles
摘要:式(i)的化合物或其药用盐:其中r1,R2和r3是各种取代基;x1和x2中的一个是n或cr',另一个是nr'或chr',其中r'是氢,Oh,C1-6烷基或c3-7环烷基;或者当x1和x2中的一个是n或cr'时,另一个可以是s或o;以及它们作为药物的用途.

专利信息

专利号:US-2023096053-A1
优先权日:2019-12-06
标 题:Genetically-targeted chemical assembly: building functional structures and materials in living cells, tissues, and animals
发明人：DEISSEROTH KARL A; BAO ZHENAN; LIU JIA; RAMAKRISHNAN CHARU; KIM YOON SEOK; TOM ARIANE C
权利人:UNIV LELAND STANFORD JUNIOR
摘要:Compositions and methods are provided for genetically modifying cells to guide in situ chemical synthesis of electroactive, conductive, or insulating polymers on plasma membranes, organelle membranes, or subcellular surfaces of cells. In particular, compositions and methods are provided for genetically modifying excitable cells such as neurons, muscle cells, and endocrine cells to guide in situ chemical synthesis of polymers on the extracellular side of the plasma membrane. The subject methods can be used in various applications, for example, to assemble polymers in vivo at targeted locations to modulate electrical conduction and create new electrical conduction pathways, allow cell-type-specific neuromodulation, provide a conductive structure on cells for connection to electrodes, sensors, or other external electronic and electrochemical devices, and create a durable structure to replace damaged tissue for use in regenerative medicine.

专利号:US-12435312-B2
优先权日:2022-02-28
标 题 :Quantifying cell-derived changes in collagen synthesis, alignment, and mechanics in a 3D connective tissue model
发明人：MORGAN JEFFREY R; WILKS BENJAMIN T
权利人:UNIV BROWN
摘要:Described herein are in vitro quantitative methods directed to 3D extracellular matrix (ECM) organization and mechanics. The methods do not require application of an external force, anchorage, or a scaffolding material in order to culture ECM tissue constructs, and the methods enable quantitative measurements without crosstalk noise from variables attributable to external forces, anchorage, and scaffolding material.

专利号:WO-2022191130-A1
优先权日:2021-03-08
标 题:Method for proliferating cardiomyocytes, method for producing cardiomyocytes, and cardiomyocyte proliferating agent
发明人：YAMASHITA JUN; YOSHIOKA MIKI
权利人:UNIV KYOTO
摘要:Provided are a method for proliferating cardiomyocytes, a method for producing cardiomyocytes, and a cardiomyocyte proliferating agent capable of contributing to cardiac regenerative medicine, that make it possible to induce proliferation of human cardiomyocytes by a drug. The method for proliferating cardiomyocytes, method for producing cardiomyocytes, and cardiomyocyte proliferating agent, including a step for culturing cardiomyocytes in the presence of one or more compounds selected from the group consisting of ALK inhibitors, cytochrome P450 omega hydroxylase inhibitors, and fatty acid synthesis inhibitors