专利号:US-9273023-B2 优先权日:2011-11-01 标 题:Modular synthesis of graphene nanoribbons and graphene substructures from oligo-alkynes 发明人:ALABUGIN IGOR; BYERS PHILIP M 权利人:UNIV FLORIDA STATE RES FOUND 摘要:A method for the synthesis of carbon-based structures, particularly graphene substructures and ribbons, from oligo- and poly-alkyne starting materials.
专利号:US-9403841-B2 优先权日:2012-01-25 标题:Phragamalin limonoids for the treatment of sexual dysfunction 发明人:WIKBERG JARL; JIRGENSONS AIGARS; LIEPINSH EDVARDS 权利人:DICOTYLEDON AB 摘要:The present invention relates to novel chemical compounds, to methods for synthesis of such compounds, and to the use of these novel compounds in the synthesis of other chemical compounds that, inter alia, may be used in the treatment of sexual dysfunction, and for eliciting enhancing effects on sexual behavior. The invention also relates to remarkable biological properties of the novel compounds in their capacity of inducing aggressive behavior.
专利号:US-11485721-B2 优先权日:2017-11-21 标 题:Method for the metal-free preparation of a biaryl by a photosplicing reaction and their uses 发明人:KLOSS FLORIAN; NEUWIRTH TONI; HAENSCH VEIT; HERTWECK CHRISTIAN 权利人:LEIBNIZ INST FUER NATURSTOFF FORSCHUNG UND INFEKTIONSBIOLOGIE E V HANS KNOELL INST HKI; LEIBNIZ INST FUER NATURSTOFF FORSCHUNG UND INFEKTIONSBIOLOGIE E V HANS KNOELL INST 摘要:The present invention relates to a method for the metal-free preparation of a biaryl compound by a photosplicing reaction and its use in the preparation of chemical compounds, preferably of active ingredients e.g. in the fields of pharmaceuticals and agrochemicals. In particular, it refers to a method for the regiocontrolled preparation of a biaryl compound of formula (I): Ar—Ar′ by photochemically reacting a precursor compound of formula (II): Ar—L—Ar′ to form a biaryl compound of general formula: Ar—L—Ar′(II)→Ar—Ar′ (I) wherein Ar and Ar′, independently of each other, represent an unsubstituted or substituted C6-C20 aryl group or a heteroaryl group with 5-20 ring atoms selected from carbon, nitrogen, oxygen and sulfur, and L represents a group —X—Y—Z— as defined herein. The biaryl compounds are generally suitable as intermediates or key building blocks in a very broad spectrum of organic chemical syntheses and their respective utilities. Their use within the field of synthesis of active ingredients is an aspect of the invention, and their use in the preparation of pharmaceutically active ingredients is particularly preferred.
专利号:US-2006009510-A1 优先权日:2004-07-09 标 题 :Method of synthesizing indolinone compounds 发明人:HAVENS JEFFREY L; VAIDYANATHAN RAJAPPA 权利人:PHARMACIA & UPJOHN CO LLC 摘要:Disclosed are methods of preparing pyrrole compounds of formula 14 and indolinone compounds of formula 1 n nvia a synthetic route wherein the amide sidechain on the pyrrole moiety is attached prior to pyrrole formation. The compounds 14 produced by the methods herein are useful in the synthesis of compounds of formula 1, which are useful in the treatment of abnormal cell growth, such as cancer.
专利号:WO-2008012852-A1 优先权日:2006-07-27 标 题:Intermediate compounds for the preparation of angiotensin ii antagonists 发明人:GUANDALINI LUCA; MARTINI ELISABETTA; ROMANELLI MARIA NOVELLA; DALLATOMASINA FRANCO 权利人:S I M S S R L SOC IT MEDICINAL; GUANDALINI LUCA; MARTINI ELISABETTA; ROMANELLI MARIA NOVELLA; DALLATOMASINA FRANCO 摘要:The present invention relates to novel substituted biphenyltetrazole compounds useful as intermediates in the preparation of angiotensin II antagonists, to a process for the synthesis of them and to a process for the conversion thereof to said molecules.
专利号:US-7429555-B2 优先权日:2004-04-30 标 题:Lubricating grease with high water resistance 发明人:SCHERER MARKUS; FISCHER MATTHIAS; MUELLER MICHAEL; KINKER BERNARD; PAUKER ALEXANDRA 权利人:ROHMAX ADDITIVES GMBH 摘要:The present invention relates to lubricating greases comprising at least one thickening agent and at least one lubricating oil, wherein the lubricating grease contains at least one polymeric structure improver that can be obtained by polymerization of monomer compositions, which are composed ofn a) 0 to 40 wt %, relative to the weight of the monomer compositions for synthesis of the polymeric structure improvers, of at least one (meth)acrylate of formula (I) nn nin which R represents hydrogen or methyl, R 1 denotes a straight-chain or branched alkyl moiety having 1 to 5 carbon atoms,n b) 40 to 99.99 wt %, relative to the weight of the monomer compositions for synthesis of the polymeric structure improvers, of at least one (meth)acrylate of formula (II) n nin which R represents hydrogen or methyl, R 2 denotes a straight-chain or branched alkyl moiety having 6 to 30 carbon atoms,n c) 0.01 to 20 wt %, relative to the weight of the monomer compositions for synthesis of the polymeric structure improvers, of monomers containing acid groups or salts thereof, d) 0 to 59.99 wt %, relative to the weight of the monomer compositions for synthesis of the polymeric structure improvers, of comonomer.