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专利信息
专利号:WO-2004074215-A1
优先权日:2003-02-03
标 题 :Process for preparation of clopidogrel, its salts and pharmaceutical compositions
发明人:NADKARNI SUNIL SADANAND; PATEL HASMUKH MATHURBHAI
权利人:NADKARNI SUNIL SADANAND; PATEL HASMUKH MATHURBHAI
摘要:The invention discloses an improved process for racemization of methyl (R)Â(-) alpha-(2-chlorophenyl)-6,7-dihydro-thieno[3,2-c]pyridine-5(4H)-acetate , a stereoisomer formed in the synthesis of clopidogrel i.e. methyl (S)-(+)-alpha (2-chlorophenyl)-6,7-dihydro-thieno[3,2-c]pyridine-5(4H)-acetate or its salts. The invention is also for an improved process for production of clopidogrel or its pharmaceutically acceptable salts. The invention further discloses novel clopidogrel salts and pharmaceutical compositions comprising them.
专利号:EP-2078025-A2
优先权日:2006-09-22
标 题:Process for the synthesis of clopidogrel and new forms of pharmaceutically acceptable salts thereof
专利号:SI-22383-A
优先权日:2006-09-22
标 题:A new process for the synthesis of clopidogrel and a novel form of its pharmaceutically acceptable salts
专利号:MX-2009002267-A
优先权日:2006-08-28
标题:PROCEDURE AND INTERMEDIARIES FOR THE SYNTHESIS OF DERIVATIVES AND INTERMEDIARIES OF (3-ALQUIL-5-PIPERIDIN-1-IL-3,3A-DIHIDRO-PIRAZOLO [1,5-A] PIRIMIDIN-7-IL) -AMINO.
专利号:WO-2008034912-A2
优先权日:2006-09-22
标 题:Process for the synthesis of clopidogrel and new forms of pharmaceutically acceptable salts thereof
专利号:US-6991807-B2
优先权日:2000-02-24
标题 :Antibiotic composition
发明人:RUDNIC EDWARD M; ISBISTER JAMES D; TREACY JR DONALD J; WASSINK SANDRA E
权利人:ADVANCIS PHARMACEUTICAL CORP
摘要:Disclosed are antibiotic products for delivering at least two different antibiotics, wherein the products are comprised of at least three or four dosage forms with different release profiles and the at least two different antibiotics comprise at least one protein synthesis inhibiting antibiotic and at least one non-protein synthesis inhibiting antibiotic.