CAS: 23150-65-4; H-Glu(Ome)-Ome.Hcl

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CAS号67-56-1 甲醇 | CAS号56-86-0 L-谷氨酸 | CAS号75-77-4 三甲基氯硅烷 | CAS号129421-88-1 Lascivol | CAS号138-15-8 L-谷氨酸盐酸盐 | CAS号1499-55-4 L-谷氨酸-5-甲酯 | CAS号77-76-9 2,2-二甲氧基丙烷 | CAS号617-65-2 DL-谷氨酸 | CAS号4271-30-1 N-(4-氨基甲酰)-L-谷氨酸 | CAS号4931-66-2 L-焦谷氨酸甲酯 | CAS号192314-71-9 (S)-2-[双(B°C)氨基... | CAS号56-86-0 L-谷氨酸 | CAS号259655-31-7 DIMETHYL 2-(1H-... | CAS号6525-53-7 谷氨酸二甲酯 | CAS号59279-60-6 N-叔丁氧羰基-L-谷氨酸二甲酯 | CAS号162955-48-8 (S)-(-)-2-(B°C-... | CAS号192655-69-9 dimethyl (2S)-2... | CAS号45234-02-4 L-赖氨酸-L-谷氨酸盐

甲醇,L-谷氨酸置于氯代叔丁烷体系中,化学反应生成L-谷氨酸二甲酯盐酸盐
参考文献:毒素a及其立体异构体的全合成及其生物学活性的发现
标题:毒素a及其立体异构体的全合成及其生物学活性的发现
摘要:已经成功实现了纤溶酶a及其三种立体异构体的首次合成.合成方法涉及酰胺向酮酰胺基团的分子内亲核环化,以产生c-羟基二酮哌嗪骨架.最令人惊讶的发现是,Ta的四种立体异构体中的每一种均表现出不同的植物毒,杀真菌和抗病毒活性.
Doi:10.1021/ol4026556

专利信息

专利号:US-9422321-B2
优先权日:2010-09-07
标题 :Pyrimidine nucleoside derivatives, synthesis methods and uses thereof for preparing anti-tumor and anti-virus medicaments
发明人：CHANG JUNBIAO; AN HAOYUN; YU XUEJUN; GUO XIAOHE
权利人:CHANG JUNBIAO; AN HAOYUN; YU XUEJUN; GUO XIAOHE; HIGH & NEW TECH RES CENTER HENAN ACAD OF SCIENCES; ZHENGZHOU GRANLEN PHARMATECH LTD; UNIV ZHENGZHOU
摘要:The present invention relates to the field of pharmacochemistry. Disclosed are fluorinated and azido-substituted pyrimidine nucleoside derivatives, particularly compounds of the formula shown below: n nAlso disclosed are methods of preparation and uses for these compounds. The compounds can be used for preparing medicaments for treating diseases such as tumors and viral infections, and can be used separately or in combination with other medicaments. The compounds also have effective activity against diseases such as tumors and viral infections, while having few side effects, and thus have potential application value.

专利号:US-9481678-B2
优先权日:2015-02-09
标题 :Substituted pyrrolo[2,3-D]dipyrimidines for selectively targeting tumor cells with FR-alpha and FR-beta type receptors
发明人：GANGJEE ALEEM; MATHERLY LARRY H
权利人:DUQUESNE UNIV OF THE HOLY GHOST; UNIV WAYNE STATE
摘要:Pyrrolo[2,3-d]pyrimidine derivatives, and pharmaceutical acceptable salts thereof, useful in therapeutically treating patients with cancer are disclosed. These compounds selectively target folate receptors (FR) of cancerous tumor cells and inhibit purine synthesis and hence, DNA synthesis.

专利号:US-8193156-B1
优先权日:2006-05-18
标 题:Dipeptides incorporating selenoamino acids with enhanced bioavailability—synthesis, pharmaceutical and cosmeceutical applications thereof
发明人：MAJEED MUHAMMED; NAGABHUSHANAM KALYANAM; RAMANUJAM RAJENDRAN; CHANDRAMOULI RENUKESHWAR H
权利人:MAJEED MUHAMMED; NAGABHUSHANAM KALYANAM; RAMANUJAM RAJENDRAN; CHANDRAMOULI RENUKESHWAR H; SAMI LABS LTD
摘要:Disclosed is a novel synthetic method for isomeric peptides through an appropriate linkage of L-selenomethionine or Se-Methyl-L-selenocysteine with L-glutamic acid. The novel synthetic method produces isomeric peptides of L-selenomethionine or Se-Methyl-L-selenocysteine that exhibit (i) enhanced water solubility; (ii) enhanced rate of dissolution in water; (iii) enhanced bioavailability; (iv) excellent vascular endothelial growth factor promoting activity; (v) excellent anti-5-alpha-reductase activity; (vi) capabilities to prevent/reduce “hair fall†and promote “hair growth†, thereby maintaining a perfect homeostasis for “hair care†. Cosmeceutical and pharmaceutical compositions comprising the isomeric peptides obtained through an appropriate linkage of L-selenomethionine or Se-Methyl-L-selenocysteine with L-glutamic acid are also disclosed. Other dipeptides with several other amino acids and uses thereof are also disclosed.

专利号:US-2025163089-A1
优先权日:2023-11-17
标 题:Branched Molecules for Redox Flow Batteries
发明人：EVANS PAUL; SISTO THOMAS; BENCIVENGA ANTHONY; CHAMPSAUR ANOUCK
权利人:XL BATTERIES INC
摘要:Compounds with redox molecular cores and branched molecular tails comprising ionic functionalities for uses as electrolytes in redox flow batteries are described, as well as methods of synthesis and use thereof. The compounds have redox active perylene diimide or ferrocene molecular core decorated with the branched molecular tails having multiple ionic functionalities to improve water solubility of the molecular core, and, as such, its performance as the electrolyte.

专利号:CN-118580159-A
优先权日:2024-05-21
标 题:Synthesis method of nitrogen heterocyclic aromatic hydrocarbon modified beta-amino acid ester

专利号:CZ-2002632-A3
优先权日:1999-08-24
标题:Synthesis method of rhinovirus protease inhibitors and key intermediates