CAS: 92-32-0; 3,6-Bis(Dimethylamino)Xanthylium Chloride

该化合物是属于Xanthene染料类的合成染料,其特征是其充满活力的红色和粉色色,它有助于各种应用,包括生物污点和pH指标. 苯丙胺在水和有机溶剂中表现出溶解性,这提高了其在实验室环境中的多功能性.该化合物经常用于植物学和细胞学中,用于染色核糖酸,特别是RNA,因为它与这些生物分子有密切关系. 苯丙胺的结构具有一种苯乙烯骨骼,有助于其染色特性,使其能够吸收特定的光波长.此外,必须小心处理苯丙胺,因为如果浸入或吸入,可能会对健康造成危害,而且在其使用期间应当采取适当的安全措施.

结构式图片

欧盟法规

ECHA物质C&L通报REACH预注册

上下游产品

βCD.PY+3,N3,N6,N6-tetramethyl-9H-xanthene-3,6-diamineN3,N3,N6,N6-tetramethyl-9H-xanthene-3,6-diamine N,N,N',N'-tetramethylrhodamine xanthone

合成工艺路线路线简述

  • 56860-23-2 = 92-32-0
    反应条件:1.1 Reagents: Lithium Aluminum Hydride Solvents: Tetrahydrofuran; Overnight,Rt1.2 Reagents: Water; Rt
    标题:Hypochlorous Acid Ratiometric Fluorescent Probe For Detecting Dental Pulp State,And Its Synthesis Method
    参考文献:China]

    53510-49-9 + 56860-23-2 = 92-32-0
    反应条件:1.1 Reagents: Iodine
    标题:Improved Xanthone Synthesis,Stepwise Chemical Redox Cycling
    作者:Bachman,James L.; Escamilla,P. Rogelio; Boley,Alexander J.; Pavlich,Cyprian I.; Anslyn,Eric V.
    参考文献:Organic Letters 日期:2019 卷标:21(1) 页码:206-209
66βcd2Succ.Py+ 反应生成 焦宁y,66βcd2Suc
参考文献:Supramolecular Chemistry Of Pyronines B And Y,β-Cyclodextrin And Linked β-Cyclodextrin Dimers
标题:Supramolecular Chemistry Of Pyronines B And Y,β-Cyclodextrin And Linked β-Cyclodextrin Dimers
摘要:阳离子吡罗宁 B (Pb+) 和吡罗宁 Y (Py+) 与 β-环糊精 (βcd)和两种连接的 βcd 二聚体 N,N'-双((2As,3As)-3A-脱氧-β-环糊精-3A-基)琥珀酰胺的络合,通过紫外可见光谱,荧光光谱和 1H NMR 光谱对水溶液中的 N,N'-双((2As,3As)-3A-脱氧-β-环糊精-3A-基)琥珀酰胺 33βcd2Suc 和 N,N'-双(6A-脱氧-β-环糊精-6A-基)琥珀酰胺 66βcd2Suc 进行了研究.报告了 1:1 复合物:βcd.Pb+,33βcd2Suc.Pb+,66βcd2Suc.Pb+ 和类似的 Py+ 复合物的络合常数,以及 Pb+ 和 Py+ 的二聚常数.报告还讨论了络合,二聚化和荧光淬灭的模式.
DOI:10.1071/ch09467

专利信息


专利号:WO-2024153642-A1
优先权日:2023-01-16
标题 :Scarless template-free enzymatic synthesis of polynucleotides
发明人:HORGAN ADRIAN; VERARDO DAMIANO; ADELIZZI BEATRICE; RODRIGUEZ-PINZON DANIEL; THOMEE EMMA
权利人:DNA SCRIPT
摘要:Methods are provided for template-free enzymatic synthesis of polynucleotides on a solid support using double cleavage to produce scarless polynucleotides. In particular, methods are disclosed that use an initiator that comprises a cleavable group, which can be cleaved by a small molecule chemical agent, adjusting pH, heat, or photocleaved by illumination with light to release polynucleotides from a solid support after enzymatic synthesis is completed, and an enzymatic cleavage site, which can be cleaved by a cleavage enzyme to remove polynucleotide scars.

专利号:EP-1494680-B1
优先权日:2002-03-25
标题 :Use of carbon-2-modified-vitamin d analogs to induce the formation of new bone
发明人:DELUCA HECTOR F; PIKE J WESLEY; SHEVDE NIRUPAMA K
权利人:WISCONSIN ALUMNI RES FOUND
摘要:It has been discovered that the 2-carbon-modified derivatives of 1α,25-dihydroxyvitamin D3 specifically stimulate osteoblasts to form new bone. The ability of the 2-carbon-modified vitamin D analogs to stimulate new bone formation suggest that these compounds can be used where synthesis of new bone is required. Thus, these compounds can be used either systemically or locally to stimulate the growth of bone transplants, to increase the rate of fracture healing and thereby reduce the time required for the healing of fractures, the stimulation of bone growth when required for replacement surgery, and also for the growth of bone to implants or other devices required to maintain the skeleton or teeth in the proper positions.

专利号:US-8802380-B2
优先权日:2007-06-04
标 题 :Method for testing or screening protein synthesis inhibitors
发明人:DREYFUSS GIDEON; KASIM MUMTAZ
权利人:DREYFUSS GIDEON; KASIM MUMTAZ; UNIV PENNSYLVANIA
摘要:This invention provides methods for screening an inhibitor of protein synthesis by measuring the level of relocalization of an SMN complex component from the cytoplasm to the nucleus. Additionally, the invention provides a kit and a system for screening protein synthesis inhibitors in a cell.

专利号:WO-9808865-A1
优先权日:1996-08-30
标 题:CAP-BINDING DOMAIN OF HUMAN EUKARYOTIC PROTEIN SYNTHESIS INITIATION FACTOR eIF-4E AND THE USE THEREOF
发明人:GOSS DIXIE J; FRIEDLAND DIANA
权利人:LIFE TECHNOLOGIES INC; GOSS DIXIE J; FRIEDLAND DIANA
摘要:Binding of eIF-4E to the 5'm7G cap structure of eukaryotic mRNA signals the initiation of protein synthesis. In the present invention, the binding site cap-binding domain of eIF-4E was identified as the region containing the sequence Trp?113 to Arg122¿. Thus, in a first preferred embodiment the present invention provides a truncated peptide of the cap binding protein consisting essentially of the mRNA cap-binding domain. Specifically, the invention concerns eIF-4E cap binding peptide and its variants. In additional preferred embodiments, the invention provides an isolated nucleic acid molecule which encodes a truncated peptide of the eIF-4E protein consisting essentially of the mRNA cap-binding domain of eIF-4E; a recombinant vector and host cell comprising the above-described nucleic acid molecule; and a recombinant peptide produced thereby. The invention further provides the truncated or recombinant peptides immobilized on a solid support, a resin comprising the truncated or recombinant peptides immobilized on a solid support, methods and kits for isolating a capped mRNA molecule, and methods and kits for producing a full-length cDNA molecule.

专利号:US-2018312534-A1
优先权日:2015-10-16
标题:Fluorescent anticancer platinum drugs
发明人:SARKAR ARINDAM; MANDAL SWADHIN KUMAR; SENGUPTA ANIRUDDHA; BISWAS GOUTAM; DUTTA PRADIP; SHARMA RUPALI; RAJ JUSTIN PAUL; SURYAVANSHI HEMANT; KUMARI SMITA
权利人:INVICTUS ONCOLOGY PVT LTD
摘要:The present disclosure is in relation to the field of nanotechnology and cancer therapeutics. In particular, the present disclosure relates to fluorescent platinum based compounds. The disclosure further relates to synthesis of said fluorescent platinum based compounds, nanoparticles and compositions comprising said fluorescent platinum based compounds/nanoparticles. The disclosure also relates to methods of managing cancer by the fluorescence changes between aforesaid platinum based compounds and corresponding free ligands, nanoparticles and compositions.

专利号:US-2023097824-A1
优先权日:2020-05-08
标 题:Semi-synthesis and use of racemic hematoxylin
发明人:DURRANT EDWARD E; HEINDL DIETER; HUBER FLORIAN MAURITIUS ERASUMU; KLEIN ERIC; KOSMEDER II JEROME W; VOSS EDGAR
权利人:VENTANA MED SYST INC; ROCHE DIAGNOSTICS OPERATIONS INC
摘要:A racemic hematoxylin formulation is disclosed that includes one or both of a stabilizer compound and an antioxidant. The disclosed composition exhibits sufficient stability to be utilized in an automated staining process. Methods of using and making the stabilized composition also are disclosed.
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合成参考文献


参考文献:10.1186/bcr2479
摘要:Lagadec C, Vlashi E, Della Donna L, Meng Y, Dekmezian C, Kim K, Pajonk F. Survival and self-renewing capacity of breast cancer initiating cells during fractionated radiation treatment. Breast Cancer Res. 2010;12(1):R13.
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