CAS: 896134-06-8; (E)-4-((5,6-Dimethoxy-1-Oxo-1,3-Dihydro-2H-Inden-2-Ylidene)Methyl)Pyridine 1-Oxide

• 英文名称(E)-4-((5,6-Dimethoxy-1-Oxo-1,3-Dihydro-2H-Inden-2-Ylidene)Methyl)Pyridine 1-Oxide
• 中文名称多奈哌齐杂质P
• IUPAC名称(E)-4-((5,6-dimethoxy-1-oxo-1,3-dihydro-2H-inden-2-ylidene)methyl)pyridine 1-oxide
• 其它别名2,3-Dihydro-5,6-Dimethoxy-2-[(1-Oxido-4-Pyridinyl)Methylene]-1H-Inden-1-One; 4-((5,6-Dimethoxy-1-Oxo-1,3-Dihydro-2H-Inden-2-Ylidene)Methyl)Pyridine 1-Oxide; Donepezil Impurity P; Donepezil Alkene Pyridine N-Oxide (Usp); Donepezil Pyridine Dehydro N-Oxide; Doneprzil Pyridine Dehydro N-Oxide; Donepezil Impurity 3/donepezil Alkene Pyridine N-Oxide/donepezil Pyridine Dehydro N-Oxide/(E)-4-[(5,6-Dimethoxy-1-Oxo-1Hinden-2-yl)Methyl]Pyridine1-Oxide
• CAS编号896134-06-8
• 分子式:C17H15NO4分子量:297.31
• 产品CID: 1917960

• 相似结构搜索
• InChIKey: AKKASSPRDCJTET-NTUHNPAUSA-N
• InChI=1S/C17H15NO4/c1-21-15-9-12-8-13(7-11-3-5-18(20)6-4-11)17(19)14(12)10-16(15)22-2/h3-7,9-10H,8H2,1-2H3/b13-7+
• 计算化学: 氢键受体数4.0氢键供体数*可旋转键数3.0

物理性质

• 沸点595.8±50.0 °C at 760 mmHg
• 闪点314.1±30.1 °C
• 密度1.3±0.1 g/cm3
• pKa:0.95±0.10(预测)
• LogP:0.69
• 折射率1.601
• 蒸汽压0.0±1.7 mmHg at 25°C
• 溶解性Chloroform (Slightly), DMSO (Slightly, Heated), Methanol (Slightly, Heated)
• 外观形态淡黄色至黄色固体

MSDS等安全信息

• 警示词warning
• 危险描述H303 May be harmful if swallowed+H313 Skin contact may be harmful+H333 Inhalation may be harmful to the body
• 防范说明P264+P280+P305+P351+P338+P337+P313
• 安全声明H303+H313+H333

上下游产品

合成工艺路线路线简述

• 4803-74-1 = 896134-06-8
  反应条件:1.1 Reagents: Hydrogen Peroxide Solvents: Acetic Acid; 2 - 3 H,45 - 50 °C
  标题:Synthesis Of New Piperidyl Indanone Derivatives As Anticonvulsant Agents
  作者:Siddiqui,Nadeem; Faiz Arshad,M.; Khan,Suroor A.; Ahsan,Waquar; Ali,Ruhi; Et Al
  参考文献:Medicinal Chemistry Research 日期:2012 卷标:21(6) 页码:726-733

海关参考信息

• 2901210000-乙烯
  2901220000-丙烯
  2902600000-乙苯
  2905110000-甲醇
• 💡 提示：海关信息按照顺序优先匹配，如需确认的海关信息，请参考相关资料。
• 详情请参考：📖 海关编码查询和海关进出口税则

其他信息查阅

• ➥ 象形图和危险代码
• ➥ 防范代码详解
• ➥ 危险代码说明
• ➥ Globally Harmonized System
• ➥ REACH监管