CAS: 7776-48-9; L-(+)-Fructose

相似化合物

551-68-8 17598-82-2 57-48-7

上下游产品

fructose O-acetyl-keto-L-fructosePenta-O-acetyl-keto-L-fructose dihydroxyacetone phosphate (S)-glyceraldehydemethyl β-D-fructofuranoside fructose LACTIC ACID acetone

📜果糖置于disodium Hydrogenphosphate,Potassium Dihydrogenphosphate,葡萄糖,Bakers' Yeast,硫酸体系中,用 水,溶剂黄146 作为反应溶剂,化学反应 50.0H,反应生成 L-果糖
参考文献:Synthesis Of Di-O-Isopropylidene Derivatives Of L-Fructose
标题:Synthesis Of Di-O-Isopropylidene Derivatives Of L-Fructose
摘要:
DOI:10.1016/s0008-6215(00)80782-X

专利信息

专利号:US-4623721-A
优先权日:1984-05-23
标题 :Synthesis of L-fructose and derivatives thereof
发明人：CHEN CHYI-CHENG; WHISTLER ROY L
权利人:PURDUE RESEARCH FOUNDATION
摘要:It is disclosed that L-fructose can be produced in high yield from L-sorbose. The process involves the inversion of the hydroxyl groups on carbon atoms C3 and C4 of L-sorbose to produce L-fructose. This inversion can be accomplished in simple, commercial equipment with the aid of common reagents. L-sorbose or an appropriately blocked derivative thereof is reacted so as to introduce or create a good leaving group, preferably mesyl or tosyl, at chiral carbon C3 thereby displacing the hydroxyl previously at that position. The leaving group is then displaced, preferably under alkaline conditions, in such a way that the hydroxyl oxygen atom at chiral carbon C4 attaches to chiral carbon C3, thereby displacing the leaving group while forming a 3,4-oxirane (epoxide) ring. The 3,4-oxirane ring forms in a downward position relative to the Haworth presentation thereby inverting chiral carbon C3 during formation of the 3,4-oxirane ring. n The 3,4-oxirane ring is then opened under acidic or alkaline conditions to yield a sugar ring with a hydroxyl group in a position above the sugar ring at chiral carbon C4, and a hydroxyl group in a downward position at C3. n Removal of any remaining blocking groups yields L-fructose. This may be accomplished by acid hydrolysis. n There are also disclosed novel classes of compounds which act as intermediaries in the synthesis of L-fructose.

专利号:WO-2007039492-A1
优先权日:2005-09-26
标 题:Efficient synthesis of asymmetric epoxidation catalyst i
发明人：VIDAL I FERRAN ANTON; NIETO ALONSO NATALIA; MOLA PORQUERAS PINEDA
权利人:INST CATALA D INVESTIGACIO QUI; ICREA; VIDAL I FERRAN ANTON; NIETO ALONSO NATALIA; MOLA PORQUERAS PINEDA
摘要:A process for the preparation of chiral ketone I from diol II comprising the acetylation of diol II with an acetylating agent, preferably an acetic acid derivative, wherein said acetylation is performed in the presence of a Lewis acid. The process can further comprise additional previous steps, so that chiral ketone I can be prepared in four steps starting from D-fructose. Alternatively, a process for the preparation of chiral ketone V from diol VI comprising the acetylation of diol VI with an acetylating agent, preferably an acetic acid derivative, wherein said acetylation is performed in the presence of a Lewis acid. The process can further comprise additional previous steps, so that chiral ketone V can be prepared starting from L-fructose, L-sorbose or D-arabinose.

专利号:EP-3538239-A1
优先权日:2016-11-11
标 题 :Synthesis of d-allulose

专利号:WO-2024226703-A2
优先权日:2023-04-27
标题:Asymmetric synthesis and diversification of a stabilized salvinorin a scaffold

专利号:US-11248016-B2
优先权日:2014-04-04
标 题:Glycolipids and pharmaceutical compositions thereof for use in therapy
发明人：BOTTLEY ANDREW; HAYES CHRISTOPHER; SEYMOUR GRAHAM; GRABOWSKA ANNA; CLARKE PHILIP
权利人:UNIV NOTTINGHAM
摘要:The invention may provide, in part, compounds for use as antiproliferative, chemotherapeutic, antiviral, cell sensitising or adjuvant agents, and pharmaceutical compositions including the compounds. The compounds may be for use in treating diseases and disorders related to cell proliferation such as cancer, or in treating diseases and disorder which are linked to aberrant control of protein synthesis, such as cancer, viral infection, muscle wasting, autistic spectrum disorders, Alzheimer's disease, Huntingdon's disease and Parkinson's disease.