CAS: 76283-09-5; 4-Bromo-1-(Bromomethyl)-2-Fluorobenzene

上下游产品

CAS号51436-99-8 4-溴-2-氟甲苯 | CAS号193290-19-6 2-氟-4-溴苯乙酸甲酯 | CAS号114897-91-5 2-氟-4-溴苯乙腈 | CAS号1000668-71-2 2-(4-bromo-2-fl... | CAS号338454-98-1 4-(4-溴-2-氟苄基)吗啉 | CAS号134057-96-8 3-(4-Bromo-2-fl... | CAS号112733-28-5 ETHYL [3-(4-BRO... | CAS号72702-95-5 波来瑞斯 | CAS号749928-77-6 2-(4-溴-2-氟苯基)-2-甲基丙腈 | CAS号749928-88-9 1-(2-氟-4-溴苯基)环丙烷甲腈 | CAS号872422-15-6 1-(4-溴-2-氟苯基)环丙甲酸

4-溴-2-氟苄醇置于氢溴酸体系中,化学反应 0.17H,以91%的收率获得产物4-溴-2-氟苄溴
参考文献:Method For Producing 4-Borono-L-Phenylalanine Having 18F Atom Introduced Thereinto,And Precursor Of 4-Borono-L-Phenylalanine Having 18F Atom Introduced Thereinto
标题:Method For Producing 4-Borono-L-Phenylalanine Having 18F Atom Introduced Thereinto,And Precursor Of 4-Borono-L-Phenylalanine Having 18F Atom Introduced Thereinto
摘要:18F标记的4-硼苯丙氨酸(bpa)可以通过制备和进一步处理以下公式代表的18F标记的bpa前体来生产: 其中r1代表溴基,碘基,氟基,二氮硼杂环衍生物,Bx3−或bx3−m+(其中x代表卤素原子;m+代表一价单原子阳离子,多原子阳离子或复合阳离子).

专利信息

专利号:US-9073935-B2
优先权日:2011-11-11
标 题:Substituted benzylspiroindolin-2-one analogs as positive allosteric modulators of the muscarinic acetylcholine receptor M1
发明人：LINDSLEY CRAIG W; CONN P JEFFREY; WOOD MICHAEL R; HOPKINS COREY R; MELANCON BRUCE J; POSLUSNEY MICHAEL S
权利人:UNIV VANDERBILT
摘要:In one aspect, the invention relates to substituted benzylspiroindolin-2-one analogs compounds, derivatives thereof, and related compounds, which are useful as positive allosteric modulators of the muscarinic acetylcholine receptor M 1 (mAChR M 1 ); synthesis methods for making the compounds; pharmaceutical compositions comprising the compounds; and methods of treating neurological and psychiatric disorders associated with muscarinic acetylcholine receptor dysfunction using the compounds and compositions. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention.

专利号:US-7999090-B2
优先权日:2000-07-07
标 题:Fungal cell wall synthesis gene
发明人：TSUKAHARA KAPPEI; HATA KATSURA; SAGANE KOJI; NAKAMOTO KAZUTAKA; TSUCHIYA MAMIKO; WATANABE NAOAKI; OHBA FUMINORI; TSUKADA ITARU; UEDA NORIHIRO; TANAKA KEIGO; KAI JUNKO
权利人:EISAI R&D MAN CO LTD
摘要:The present invention provides isolated DNA encoding a GWT1 protein having activity to confer resistance of a fungus against a compound of formula Ia, and wherein a defect of a function of the GWT1 protein leads to a decrease in the amount of a glycosylphosphatidylinositol (GPI)-anchored protein in the cell wall of a fungus.

专利号:US-9012445-B2
优先权日:2012-01-12
标题 :Substituted 4-(1H-pyrazol-4-yl)benzyl analogues as positive allosteric modulators of mAChR M1 receptors
发明人：LINDSLEY CRAIG W; CONN P JEFFREY; WOOD MICHAEL R; MELANCON BRUCE J; POSLUSNEY MICHAEL S; TARR JAMES C
权利人:UNIV VANDERBILT
摘要:In one aspect, the invention relates to substituted 4-(1H-pyrazol-4-yl)benzyl analogs compounds, derivatives thereof, and related compounds, which are useful as positive allosteric modulators of the muscarinic acetylcholine receptor M 1 (mAChR M 1 ); synthesis methods for making the compounds; pharmaceutical compositions comprising the compounds; and methods of treating neurological and psychiatric disorders associated with muscarinic acetylcholine receptor dysfunction using the compounds and compositions. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention.

专利号:US-9029563-B2
优先权日:2012-01-06
标题:Substituted 1-benzylindolin-2-one analogs as positive allosteric modulators of muscarinic acetylcholine M1 receptors
发明人：LINDSLEY CRAIG W; CONN P JEFFREY; WOOD MICHAEL R; MELANCON BRUCE J; POSLUSNEY MICHAEL S
权利人:UNIV VANDERBILT
摘要:In one aspect, the invention relates to substituted 1-benzylindolin-2-one analog compounds, derivatives thereof, and related compounds, which are useful as positive allosteric modulators of the muscarinic acetylcholine receptor M 1 (mAChR M 1 ); synthesis methods for making the compounds; pharmaceutical compositions comprising the compounds; and methods of treating neurological and psychiatric disorders associated with muscarinic acetylcholine receptor dysfunction using the compounds and compositions. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention.

专利号:US-9586964-B2
优先权日:2011-10-28
标 题:Substituted 2-(4-heterocyclylbenzyl)isoindolin-1-one analogs as positive allosteric modulators of the muscarinic acetylcholine receptor M1
发明人：LINDSLEY CRAIG W; CONN P JEFFREY; WOOD MICHAEL R; HOPKINS COREY R; MELANCON BRUCE J; POSLUSNEY MICHAEL S; ENGERS DARREN W
权利人:UNIV VANDERBILT
摘要:In one aspect, the invention relates to substituted 2-(4-heterocyclylbenzyl)isoindolin-1-one analogs compounds, derivatives thereof, and related compounds, which are useful as positive allosteric modulators of the muscarinic acetylcholine receptor M 1 (mAChR M 1 ); synthesis methods for making the compounds; pharmaceutical compositions comprising the compounds; and methods of treating neurological and psychiatric disorders associated with muscarinic acetylcholine receptor dysfunction using the compounds and compositions. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention.

专利号:RU-2184110-C2
优先权日:1996-12-23
标 题 :Derivatives of nitromethylthiobenzene, method of their synthesis (versions) and pharmaceutical composition