📜(+/-)-2-(Chloroacetyl-Amino)-3-[2]Thienyl-Propionic Acid置于氢溴酸体系中,化学反应生成 3-(2-噻吩基)-D-丙氨酸 参考文献:Studies On The Chemistry Of Heterocyclics. Viii. Enzymatic Resolution Of Racemic β-2-Thienylalanine And Preparation Of Some Substituted β-2-Thienylalanines1 标题:Studies On The Chemistry Of Heterocyclics. Viii. Enzymatic Resolution Of Racemic β-2-Thienylalanine And Preparation Of Some Substituted β-2-Thienylalanines1 摘要: DOI:10.1021/jo01149A040
专利号:US-2023037284-A9 优先权日:2018-11-30 标题:Combination therapy of peptidomimetic macrocycles 发明人:GUERLAVAIS VINCENT; ANNIS DAVID ALLEN 权利人:AILERON THERAPEUTICS INC 摘要:The present disclosure describes the synthesis of peptidomimetic macrocycles and methods of using peptidomimetic macrocycles to treat a condition. The present disclosure also describes methods of using peptidomimetic macrocycles in combination with at least one additional pharmaceutically-active agent for the treatment of a condition, for example, cancer.
专利号:US-2018371021-A1 优先权日:2017-05-11 标 题 :Peptidomimetic macrocycles and uses thereof 发明人:AIVADO MANUEL; GUERLAVAIS VINCENT; OLSON KAREN 权利人:AILERON THERAPEUTICS INC 摘要:The present disclosure describes the synthesis of peptidomimetic macrocycles and methods of using peptidomimetic macrocycles to treat a condition. The present disclosure also describes methods of using peptidomimetic macrocycles in combination with at least one additional pharmaceutically-active agent for the treatment of a condition, for example, cancer.
专利号:WO-2021072167-A1 优先权日:2019-10-10 标 题:Compositions and methods for in vivo synthesis of unnatural polypeptides
专利号:US-11091522-B2 优先权日:2018-07-23 标题 :Peptidomimetic macrocycles and uses thereof 发明人:AIVADO MANUEL; GUERLAVAIS VINCENT; OLSON KAREN; ANNIS DAVID ALLEN 权利人:AILERON THERAPEUTICS INC 摘要:The present disclosure describes the synthesis of peptidomimetic macrocycles and methods of using peptidomimetic macrocycles to treat a condition. The present disclosure also describes methods of using peptidomimetic macrocycles in combination with at least one additional pharmaceutically-active agent for the treatment of a condition, for example, cancer.
专利号:EP-4041249-A1 优先权日:2019-10-10 标题 :Compositions and methods for in vivo synthesis of unnatural polypeptides
专利号:CN-114761026-A 优先权日:2019-10-10 标 题:Compositions and methods for in vivo synthesis of non-natural polypeptides