CAS: 57054-86-1; 5-Bromo-2-Chloro-N,N-Dimethylpyrimidin-4-Amine
该化合物是一种化学化合物,其特点是其火利米丁环结构,这是一个六人组成的芳香环,分别含有1和3号位置的两个氮原子. 5和2号位置分别存在溴和氯替代成分,有助于其在各种化学反应中产生反应和潜在应用.4号位置的二甲基氨基组增强了其在极溶剂中的基本性和溶性.该化合物经常用于制药研究和开发,原因是其潜在的生物活动,特别是其他生物活性分子的合成.其分子结构允许与生物目标互动,使其对医药化学感兴趣.应当参考安全数据来处理,因为卤化化合物可能会表现出毒性和环境关切.
- 英文名称5-Bromo-2-Chloro-N,N-Dimethylpyrimidin-4-Amine
- 中文名称5-溴-2-氯-N,N-二甲基嘧啶-4-胺
- IUPAC名称5-bromo-2-chloro-N,N-dimethylpyrimidin-4-amine
- 其它别名5-溴-2-氯-4-(二甲基氨基)嘧啶; 5-Bromo-2-Chloro-4-(Dimethylamino)Pyrimidine
- CAS编号57054-86-1
- MFCD编号:MFCD07781214
- 分子式:C6H7BrClN3分子量:236.5
- 产品CID: 1545110
- 产品分类有机原料→分子砌块→芳杂环类化合物→嘧啶类化合物
相似化合物
205672-24-8 31058-81-8 954221-06-8MSDS等安全信息
上下游产品
2,4-dichloro-5-bromopyrimidine dimethyl amine (2-Benzyloxy-5-bromo-pyrimidin-4-yl)-dimethyl-amine合成工艺路线路线简述
📜5-溴-2,4-二氯嘧啶,二甲胺 以 甲醇 作为反应溶剂,以73%的收率获得产物5-溴-2-氯-N,N-二甲基嘧啶-4-胺
参考文献:Wojtowicz-Rajchel,Hanna; Suchowiak,Marek; Fiedorow,Piotr,Journal Of The Chemical Society. Perkin Transactions 2 (2001),1998,# 4,P. 841-845
标题:Wojtowicz-Rajchel,Hanna; Suchowiak,Marek; Fiedorow,Piotr,Journal Of The Chemical Society. Perkin Transactions 2 (2001),1998,# 4,P. 841-845
海关参考信息
- 2921199090-其他无环单胺
- 💡 提示：海关信息按照顺序优先匹配，如需确认的海关信息，请参考相关资料。
- 详情请参考：📖 海关编码查询和海关进出口税则
专利信息
专利号:US-9795613-B2
优先权日:2014-12-10
标题 :GLP-1 receptor modulators
发明人：BOEHM MARCUS F; MARTINBOROUGH ESTHER; MOORJANI MANISHA; TAMIYA JUNKO; HUANG LIMING; YEAGER ADAM R; BRAHMACHARY ENUGURTHI; FOWLER THOMAS; NOVAK ANDREW; MEGHANI PREMJI; KNAGGS MICHAEL; GLYNN DANIEL; MILLS MARK
权利人:CELGENE INT II SÀRL
摘要:Compounds are provided that modulate the glucagon-like peptide 1 (GLP-1) receptor, as well as methods of their synthesis, and methods of their therapeutic and/or prophylactic use. Such compounds can act as modulators or potentiators of GLP-1 receptor on their own, or with incretin peptides such as GLP-1(7-36) and GLP-1(9-36), or with peptide-based therapies, such as exenatide and liraglutide, and have the following general structure (where “ â€? represents either or both the R and S form of the compound): n nwhere A, B, C, Y 1 , Y 2 , Z, R 1 , R 2 , R 3 , R 4 , R 5 , W 1 , n, p and q are as defined herein.
专利号:US-9187522-B2
优先权日:2011-12-12
标题 :GLP-1 receptor modulators
发明人：BOEHM MARCUS F; MARTINBOROUGH ESTHER; MOORJANI MANISHA; TAMIYA JUNKO; HUANG LIMING; YEAGER ADAM R; BRAHMACHARY ENUGURTHI; FOWLER THOMAS; NOVAK ANDREW; MEGHANI PREMJI; KNAGGS MICHAEL
权利人:RECEPTOS INC
摘要:The invention relates to compounds that modulate the glucagon-like peptide 1 (GLP-1) receptor, methods of their synthesis, and methods of their therapeutic and/or prophylactic use. Such compounds are act as modulators or potentiators of GLP-1 receptor on their own, or with receptor ligands including GLP-1 peptides GLP-1(7-36) and GLP-1(9-36), or with peptide-based therapies, such as exenatide and liraglutide, and have the following general structure (where “ â€? represents either or both the R and S form of the compound): n nwhere A, B, C, Y 1 , Y 2 , Z, R 1 , R 2 , R 3 , R 4 , R 5 , W 1 , n, p and q are as defined herein.
专利号:US-9598430-B2
优先权日:2013-06-11
标 题 :GLP-1 receptor modulators
发明人：BOEHM MARCUS F; MARTINBOROUGH ESTHER; MOORJANI MANISHA; TAMIYA JUNKO; HUANG LIMING; YEAGER ADAM R; BRAHMACHARY ENUGURTHI; FOWLER THOMAS; NOVAK ANDREW; MEGHANI PREMJI; KNAGGS MICHAEL
权利人:RECEPTOS INC; CELGENE INT II SÀRL
摘要:Compounds are provided that modulate the glucagon-like peptide 1 (GLP-1) receptor, as well as methods of their synthesis, and methods of their therapeutic and/or prophylactic use. Such compounds can act as modulators or potentiators of GLP-1 receptor on their own, or with incretin peptides such as GLP-1(7-36) and GLP-1(9-36), or with peptide-based therapies, such as exenatide and liraglutide, and have the following general structure (where “ â€? represents either or both the R and S form of the compound): n nwhere A, B, C, Y 1 , Y 2 , Z, R 1 , R 2 , R 3 , R 4 , R 5 , W 1 , n, p and q are as defined herein.
