CAS: 38072-88-7; Pterolactam

相似化合物

39662-63-0 62312-55-4 63853-74-7

上下游产品

2-pyrrolidinon methanol Succinimide 1-chloropyrrolidin-2-one3-Oxo-2-(5-oxo-pyrrolidin-2-yl)-3-phenyl-propionic acid ethyl ester 1-benzoyl 5-methoxy pyrrolidin-2-one 5,5-Dimethyl-2-(5-oxo-pyrrolidin-2-yl)-cyclohexane-1,3-dione (racemic)-5-(2'-propenyl)-2-pyrrolidinone

📜Dl-焦谷氨酸 反应生成 5-甲氧基-2-吡咯烷酮
参考文献:Coulton,S.;Francois,I.;Southgate,R.,Tetrahedron Lett.,31,(1990) N7,C. 6923-6926
标题:Coulton,S.;Francois,I.;Southgate,R.,Tetrahedron Lett.,31,(1990) N7,C. 6923-6926

专利信息

专利号:EP-0492350-B1
优先权日:1990-12-17
标 题 :Process for the production of (S)-vinyl and (S) allenyl gaba
发明人：EVANS JONATHAN C
权利人:MERRELL PHARMA INC
摘要:The present invention is directed to a stereospecific synthesis of (S)-vinyl-GABA, (S)-allenyl-GABA, (S)-5-allenylpyrrolidinone, and (S)-5-vinyl-pyrrolidinone. Another aspect is directed to a class of 1,5-disubstituted-pyrrolidinone intermediates as well as a new class of chiral lactic acid derivatives. t

专利号:US-5208345-A
优先权日:1990-12-17
标 题:Process for the production of (S)-vinyl and allenyl gaba
发明人：EVANS JONATHAN C
权利人:MERRELL DOW PHARMA
摘要:The present invention is directed to a new class of pyrrolidinone derivatives that are useful as chemical intermediates in the synthesis of S-allenyl and S-vinyl GABA, both of which are antiepileptic agents.

专利号:US-11472777-B2
优先权日:2015-09-14
标题:Piperazine and piperidine derivatives, their synthesis and use thereof in inhibiting VDAC oligomerization, apoptosis and mitochondria dysfunction
发明人：SHOSHAN-BARMATZ VARDA; LEV GRUZMAN ARIE
权利人:NAT INST BIOTECHNOLOGY NEGEV LTD
摘要:Provided herein piperazine and piperidine derivatives, their synthesis and use thereof in inhibiting VDAC oligomerization, apoptosis and mitochondria dysfunction. Also provided methods of treatment of diseases associated with said processes, e.g. Alzheimer's and Parkinson's diseases.

专利号:US-10508091-B2
优先权日:2015-09-14
标 题:Piperazine and piperidine derivatives, their synthesis and use thereof in inhibiting VDAC oligomerization, apoptosis and mitochondria dysfunction
发明人：SHOSHAN-BARMATZ VARDA; LEV GRUZMAN ARIE
权利人:NAT INST BIOTECHNOLOGY NEGEV LTD
摘要:Provided herein piperazine and piperidine derivatives, their synthesis and use thereof in inhibiting VDAC oligomerization, apoptosis and mitochondria dysfunction. Also provided methods of treatment of diseases associated with said processes, e.g. Alzheimer's disease.

专利号:IL-257951-A
优先权日:2015-09-14
标题 :Innovative derivatives of piperazine and piperidine, methods for their synthesis and uses as inhibitors of vdac oligomerization, apoptosis and disruption of mitochondrial activity

专利号:ES-2815539-T3
优先权日:2015-09-14
标题:New piperazine and piperidine derivatives, their synthesis and use in the inhibition of VDAC oligomerization, apoptosis and mitochondrial dysfunction