CAS: 2338-20-7; 3,4,5-Triiodobenzoic Acid

该化合物是一种芳香化合物,其特点是存在三个碘原子和一个附于苯环的碳酸组,其分子式为C7H3I3O2,反映碘,氢,碳和氧的存在;该化合物一般为室温固态,因重碘原子而以其高分子重量而闻名;它经常用于有机合成,并用作各种化学反应的试剂,特别是在医药化学和放射学领域,因为碘的特性有益;多种替代食用物的存在对其化学反应和物理特性,例如溶性及熔点有重大影响;此外,3,4,5-三叶苯并会酸可以展示生物活动,从而引起对药理学研究的兴趣;在处理该化合物时,应当采取安全防范措施,因为碘在某些形式上可能有害.

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CAS号619-58-9 对碘苯甲酸 | CAS号65-85-0 苯甲酸 | CAS号53279-79-1 3,5-二碘苯甲醇

合成工艺路线路线简述

    📜苯甲酸置于碘,过碘酸体系中,用 硫酸 用作溶剂,以31%的收率获得3,4,5-三碘苯甲酸
    参考文献:Direct Aromatic Periodination
    标题:Direct Aromatic Periodination
    摘要:
    Doi:10.1021/jo00191A003

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    专利信息


    专利号:WO-2014161072-A1
    优先权日:2013-04-02
    标题 :Α-boryl isocyanides, boropeptides and boron heterocycles
    发明人:ZAJDLIK ADAM DANIEL; YUDIN ANDREI K
    权利人:UNIV TORONTO
    摘要:This application pertains to α-boryl isocyanates, wherein the boronate moiety is in the form of an N-methyliminodiacetic acid (MIDA) boronate of the Formula (2) and the utility of said compounds in the synthesis of the borylamide motif (Î’-C-N amide ) in the scaffold of biologically-active boropeptides, such as bortezomib, in the enablement of heterocycle synthesis, and in multi-component reactions (MCRs), such as the Ugi and Passerini processes.

    专利号:US-12146028-B2
    优先权日:2016-06-06
    标 题:Iodo-functionalized polymers as mass spectrometry calibrants with a mass-defect offset
    发明人:GRAYSON SCOTT M
    权利人:THE ADMINISTRATORS OF THE TULANE EDUCATIONAL FUND; POLYMER FACTORY SWEDEN AB
    摘要:The present invention discloses novel calibrants containing between 1 and 5 iodine atoms and methods of making them using linear polymers, hyperbranched polymers, and biological polymers (including but not limited to proteins and peptides.) Methods of using the calibrants are also disclosed, such as mass spectrometry. The novel calibrants disclosed herein have a more cost- and time-efficient synthesis than other calibrants.

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    ✅ COA系统入驻 | 共享模式

    合成参考文献


    摘要:U.S. Army Armament Research & Development Command, Chemical Systems Laboratory, NIOSH Exchange Chemicals., NX#01429
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