CAS: 2109-73-1; N-[4-[(2-Methylpropan-2-yl)Oxy]Phenyl]Acetamide

该化合物是一种化学合成芳香氨衍生物,其特点是在苯环上存在一种异丁氧替代物,该化合物主要用作有机合成的中间体,特别是在研制药品和农用化学品方面,其异丁氧组别可增强消毒性和电子特性,使其对改变结合反应和功能化反应的回性具有价值.

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上下游产品

CAS号507-19-7 溴代叔丁烷 | CAS号103-90-2 对乙酰氨基苯酚 | CAS号2109-72-0 1-叔丁氧基-4-硝基苯 | CAS号350-46-9 对氟硝基苯 | CAS号57120-36-2 4-叔丁氧基苯胺

合成工艺路线路线简述

    📜4-叔丁氧基苯胺 反应生成4-丁氧基乙酰胺
    参考文献:合成哌啶系列.第二部分 哌啶醚及相关化合物的制备
    标题:合成哌啶系列.第二部分 哌啶醚及相关化合物的制备
    摘要:
    Doi:10.1039/jr9540001795

    海关参考信息

    专利信息


    专利号:US-2024287041-A1
    优先权日:2021-05-20
    标题 :Methods of synthesis of heteroaryl derivatives of triazolyl acrylamides and crystalline forms
    发明人:BALOGLU ERKAN; AUSTAD BRIAN C; ROE DAVID G; KEDUC ANDREW; GOTTSCHLING STEPHEN EDMUND; HECKER EVAN
    权利人:KARYOPHARM THERAPEUTICS INC
    摘要:The present invention relates to a method of preparing a compound represented by structural formula (VII), comprising reacting a compound represented by structural formula (II), with a compound represented by structural formula (III), in a solvent, in the presence of a Pd catalyst and one or more inorganic bases under conditions suitable to prepare a compound represented by structural formula (VII): The values and example values of the variables in structural formulas (VII), (II), and (III) are defined herein. The present invention also relates to crystalline Forms I and II of the compound represented by Structural Formula (VII), the use of the crystalline Forms in treating disease or disorders associated with CRM1 and method of preparing the crystalline Forms.

    专利号:US-2008214827-A1
    优先权日:2004-02-03
    标 题:Synthesis of Cyanoimino-Benzoimidazoles
    发明人:GOEHRING R RICHARD; WHITEHEAD JOHN; SHAO BIN
    权利人:EURO CELTIQUE SA
    摘要:Disclosed in certain embodiments is a process for synthesizing a compound of formula (V) and salts thereof.

    专利号:AU-2022276509-A1
    优先权日:2021-05-20
    标题:Methods of synthesis of heteroaryl derivatives of triazolyl acrylamides and crystalline forms

    专利号:US-9994558-B2
    优先权日:2013-09-20
    标题 :Multicyclic compounds and methods of using same
    发明人:BALOGLU ERKAN; SHACHAM SHARON; SENAPEDIS WILLIAM; MCCAULEY DILARA; LANDESMAN YOSEF; GOLAN GALI; KALID ORI; SHECHTER SHARON
    权利人:KARYOPHARM THERAPEUTICS INC
    摘要:The invention generally relates to compounds represented by Structural Formula I: or a pharmaceutically acceptable salt thereof, wherein the variables are as defined and described herein. The invention also includes the synthesis and use of a compound of structural formula I, or a pharmaceutically acceptable salt or composition thereof, e.g., in treatment of cancer (e.g., mantle cell lymphoma), and other diseases and disorders (e.g., PAK-mediated, for example, PAK4-mediated, diseases and disorders).

    专利号:WO-2022246227-A1
    优先权日:2021-05-20
    标 题:Methods of synthesis of heteroaryl derivatives of triazolyl acrylamides and crystalline forms

    专利号:WO-9943814-A1
    优先权日:1998-02-27
    标 题 :Therapeutic blockade of icer synthesis to prevent icer-mediated inhibition of immune cell activity
    发明人:COHEN PETER A; BODOR JOSEF; WENG DAVID E; KOSKI GARY K; CZERNIECKI BRIAN J; BODOROVA JANA
    权利人:US HEALTH; COHEN PETER A; BODOR JOSEF; WENG DAVID E; KOSKI GARY K; CZERNIECKI BRIAN J; BODOROVA JANA
    摘要:The present invention relates to reagents and methods for modulating immune cell activity using agents which regulate the activity of ICER.

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    品牌试剂参考报价(招募中)

    📌 第三方产品分析报告

    ✅ COA系统入驻 | 共享模式

    主要参考文献


    1: Liu F, Zhang Q, Zhu D, Li Z, Li J, Wang B, Zhou D, Dong J. Performance of Positron Emission Tomography and Positron Emission Tomography/Computed Tomography Using Fluorine-18-Fluorodeoxyglucose for the Diagnosis, Staging, and Recurrence Assessment of Bone Sarcoma: A Systematic Review and Meta-Analysis. Medicine (Baltimore). 2015 Sep;94(36):e1462. doi: 10.1097/MD.0000000000001462. Erratum in: Medicine (Baltimore). 2016 Jan;95(2):e187a. Liu, Fengxia [Added]. Erratum in: Medicine (Baltimore). 2016 Jan 15;95(2):e187a.
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