CAS: 204688-60-8; (R)-2-(1-Boc-3-Pyrrolidinyl)Acetic Acid

上下游产品

CAS号1228312-13-7 (R)-2-(1-(叔丁氧基羰... | CAS号24424-99-5 二碳酸二叔丁酯 | CAS号127423-61-4 (R)-1-B°C-3-甲磺酰氧基吡咯烷 | CAS号1228312-12-6 diethyl (R)-2-(... | CAS号1024038-31-0 (R)-2-(吡咯烷-3-基)... | CAS号1228312-14-8 (R)-3-乙烯基吡咯烷-1-羧酸叔丁酯

(R)-1-(叔丁氧基羰基)-3-吡咯烷-甲磺酸酯置于sodium Ethanolate,柠檬酸,Sodium Hydroxide体系中,用 四氢呋喃,乙醇,二甲基亚砜,甲苯 用作溶剂,化学反应 37.0H,反应生成(R)-N-Boc-3-四氢吡咯乙酸
参考文献:Ep3239143
标题:Ep3239143

专利信息

专利号:US-2025091989-A1
优先权日:2023-09-19
标 题 :Small molecule protein synthesis modulators
发明人：GYGI DAVID; BAHMANYAR SOGOLE SAMI; HAMANN LAWRENCE
权利人:INTERDICT BIO INC
摘要:The present disclosure provides compounds of the formulae herein (e.g., Formula (I)), and pharmaceutically acceptable salts thereof, which are useful for modulating protein synthesis (e.g., modulating synthesis of BCL-2, MYC, CCND1, MCL-1, ALK, KRAS-G12D). The present disclosure also provides pharmaceutical compositions and kits comprising the compounds, or pharmaceutically acceptable salts thereof, and methods of treating or preventing diseases or disorders (e.g., diseases or disorders associated with BCL-2, MYC, CCND1, MCL-1, ALK, KRAS-G12D) by administering to a subject in need thereof the compounds, or pharmaceutically acceptable salts thereof, or pharmaceutical compositions thereof.

专利号:US-9981949-B2
优先权日:2008-12-01
标题 :Synthesis and novel salt forms of (R)-5-((E)-2-pyrrolidin-3-ylvinyl)pyrimidine
发明人：AKIREDDY SRINIVASA RAO; BHATTI BALWINDER SINGH; CUTHBERTSON TIMOTHY J; DULL GARY MAURICE; MILLER CRAIG HARRISON; MITCHENER JR JOSEPH PIKE; MUNOZ JULIO A; OTTEN PIETER ALBERT
权利人:OYSTER POINT PHARMA INC
摘要:The present invention relates to the stereospecific synthesis of (R)-5-((E)-2-pyrrolidin-3-ylvinyl)pyrimidine, its salt forms, and novel polymorphic forms of these salts.

专利号:US-8604191-B2
优先权日:2008-12-01
标 题:Synthesis and novel salt forms of (R)-5-((E)-2-pyrrolidin-3YLVINYL)pyrimidine
发明人：AKIREDDY SRINIVASA RAO; BHATTI BALWINDER SINGH; CUTHBERTSON TIMOTHY J; DULL GARY MAURICE; MILLER CRAIG HARRISON; MITCHENER JR JOSEPH PIKE; MUNOZ JULIO A; OTTEN PIETER ALBERT
权利人:AKIREDDY SRINIVASA RAO; BHATTI BALWINDER SINGH; CUTHBERTSON TIMOTHY J; DULL GARY MAURICE; MILLER CRAIG HARRISON; MITCHENER JR JOSEPH PIKE; MUNOZ JULIO A; OTTEN PIETER ALBERT; TARGACEPT INC
摘要:The present invention relates to the stereospecific synthesis of (R)-5-((E)-2-pyrrolidin-3-yl)pyrimidine, novel salt forms, and novel polymorphic forms of these salts.

专利号:US-8633227-B2
优先权日:2008-12-01
标 题 :Synthesis and novel salt forms of (R)-3-((E)-pyrrolidin-3-yl)vinyl)-5-tetrahydropyran-4-yloxy)pyridine
发明人：AKIREDDY SRINIVASA RAO; BREINING SCOTT R; CUTHBERTSON TIMOTHY J; DULL GARY MAURICE; GATTO GREGORY J; GENUS JOHN; HAMMOND PHILIP S; MITCHENER JR JOESPH PIKE; MUNOZ JULIO A; OTTEN PIETER ALBERT; YOHANNES DANIEL; FEDOROV NIKOLAI
权利人:AKIREDDY SRINIVASA RAO; BREINING SCOTT R; CUTHBERTSON TIMOTHY J; DULL GARY MAURICE; GATTO GREGORY J; GENUS JOHN; HAMMOND PHILIP S; MITCHENER JR JOESPH PIKE; MUNOZ JULIO A; OTTEN PIETER ALBERT; YOHANNES DANIEL; FEDOROV NIKOLAI; TARGACEPT INC
摘要:The present invention relates to (R)-3-((E)-2-(pyrrolidin-3-yl)vinyl)-5-(tetrahydropyran-4-yloxy)pyridine, its salt forms, and to processes for the commercial-scale production of these compounds in sufficient purity and quality for use in pharmaceutical compositions.

专利号:US-2024246936-A1
优先权日:2008-12-01
标 题 :Synthesis and novel salt forms of (r)-5-((e)-2-(pyrrolidin-3-ylvinyl)pyrimidine

专利号:US-2020207740-A1
优先权日:2008-12-01
标题 :Synthesis and novel salt forms of (r)-5-((e)-2-pyrrolidin-3-ylvinyl)pyrimidine