CAS: 96-41-3; Cyclopentanol

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CAS号98-00-0 糠醇 | CAS号120-92-3 环戊酮 | CAS号98-01-1 糠醛 | CAS号14320-38-8 3-环戊烯-1-醇 | CAS号1003-03-8 环戊胺 | CAS号285-67-6 氧化环戊烯 | CAS号85382-33-8 2H-Pyran,2-(cyc... | CAS号39852-66-9 hydroperoxycycl... | CAS号135746-46-2 (9CI)-(环戊基氧基)(1... | CAS号2883-45-6 1,6-庚二烯-4-醇 | CAS号111711-86-5 1-(benzenesulfo... | CAS号3400-45-1 环戊甲酸 | CAS号50715-28-1 氯甲酸环戊酯 | CAS号542-28-9 δ-戊内酯 | CAS号85382-33-8 2H-Pyran,2-(cyc... | CAS号85382-32-7 formic acid,4-i... | CAS号35435-67-7 1,4-butanediol ... | CAS号572924-00-6 N-环戊氧羰基-L-叔亮氨酸 | CAS号98-85-1 苏合香醇

氯代环戊烷置于水,Lithium Perchlorate,Sodium Hydroxide体系中,用 N,N-二甲基乙酰胺,乙腈 作为反应溶剂,化学反应生成 环戊醇
参考文献:在n,N-二甲基甲酰胺和n,N-二甲基乙酰胺-水混合溶剂中盐对有机卤化物溶剂分解反应速率和机理和水结构畸变的影响
标题:在n,N-二甲基甲酰胺和n,N-二甲基乙酰胺-水混合溶剂中盐对有机卤化物溶剂分解反应速率和机理和水结构畸变的影响
摘要:在 50% (V/v) Dmf 和 Dmah2 混合溶剂中,已检查盐对脂族内酯和相关化合物 (Rx) 的溶剂分解反应速率的影响,以供进一步探索.与之前在其他有机溶剂系统(如 50% (V/v) 丙酮,1,4-二恶烷或环丁砜)中获得的结果相比,在"伪"一级速率常数 (K/通过在 5 0% (V/v) Dmf 和 Dmah2 O 混合溶剂中添加碱金属和碱土金属高氯酸盐或多种四烷基铵盐,S 11) 1-金刚烷基溴的 βlog(K/s ¹1)/βliclo4] 与有机溶剂(ch3Cn,Dma,和 Dmso) 表明观测到的不同盐效应是由溶剂对离去基团阴离子和金属阳离子的不同溶剂化能力引起的.作为本文的一个新亮点,我们能够证明 Liclo4 对溶剂分解速率的影响与气相中 Rx 的吉布斯自由能值 (βg O) 表示的碳正离子稳定性之间的比例或相关性.基于 Dmah2O 和 Dmad2 Oa 以及 Dmfd2
DOI:10.1246/bcsj.20090329

专利信息

专利号:US-2024092821-A1
优先权日:2020-03-31
标题:Synthesis of oligonucleotides and related compounds
发明人：ZHONG MINGHONG; JIN YI; GALA DINESH; PRHAVC MARIJA
权利人:JANSSEN BIOPHARMA INC
摘要:Methods of synthesizing oligonucleotides via new intermediates on a cleavable support having an azidomethyl moiety are disclosed. The method comprises multiple reaction cycles, each of which comprises sequential coupling a nucleoside or oligonucleotide subunit on a cleavable support having an azidomethyl moiety and a nucleoside phosphoramidite or an oligonucleotide phosphoramidite, capping, oxidation/thiolation and deblocking; followed by orthogonal cleavage of the azidomethyl support while keeping all other protecting groups intact. The method can be used in combination with a support moiety for either solid phase or liquid phase oligo synthesis. The soluble support facilitates homogeneous reactions and efficient separations by simple precipitation. The methods also provide novel intermediates useful in the synthesis of oligonucleotide conjugates.

专利号:US-2021107859-A1
优先权日:2018-04-06
标题 :A process for the synthesis of carbon labeled organic compounds
发明人：AUDISIO DAVIDE; CANTAT THIBAULT; DESTRO GIANLUCA
权利人:COMMISSARIAT ENERGIE ATOMIQUE
摘要:A process for the synthesis of a carbon labeled organic compound containing a carbon labeled carboxyl group is described. A method of using carbon labeled organic compounds containing a carbon labeled carboxyl group according to the present disclosure; a process for manufacturing labeled pharmaceuticals and agrochemicals comprising synthesis of carbon labeled organic compounds containing a carbon labeled carboxyl group according to the present disclosure; and a process for producing tracers comprising synthesis of carbon labeled organic compounds containing a carbon labeled carboxyl group according to the present disclosure are also described.

专利号:US-2012302756-A1
优先权日:2010-02-19
标 题 :Process for synthesis of 2-substituted pyrrolidines and piperadines
发明人：LELETI RAJENDER REDDY; LIU YUGANG; PRASHAD MAHAVIR
权利人:LELETI RAJENDER REDDY; LIU YUGANG; PRASHAD MAHAVIR
摘要:The present invention provides a highly efficient, versatile one-step process for asymmetric synthesis of either diastereomer of 2-substituted pyrrolidines from a single starting material with excellent yields and high diastereoselectivety. Also provided is a method for the asymmetric synthesis of both diastereomers of 2-substituted piperidines with good yields and excellent diastereoselectivety. Diasteroselectivity is controlled effectively by choice of reducing agent.

专利号:US-8445713-B2
优先权日:2007-10-22
标 题 :Catalyst for the synthesis of organic carbonates, process for preparing the same and application thereof
发明人：WERSHOFEN STEFAN; KLEIN STEPHAN; ZHOU ZHIPING; WANG XINKUI; WANG JUNWEI; KANG MAOQING
权利人:WERSHOFEN STEFAN; KLEIN STEPHAN; ZHOU ZHIPING; WANG XINKUI; WANG JUNWEI; KANG MAOQING; BAYER MATERIALSCIENCE AG
摘要:The present invention relates to a catalyst for the synthesis of organic carbonates, the preparation of the catalyst and the application of this catalyst in the synthesis of organic carbonates from reacting urea and hydroxyl group containing compounds. The catalyst provided in this invention is a calcinate of hydrous salt containing rare earth element at a moderate calcining temperature.

专利号:EP-2607355-A1
优先权日:2011-12-23
标 题:Synthesis of triazolopyrimidine compounds
权利人:LEK PHARMACEUTICALS
摘要:The present invention relates to the field of organic synthesis and describes the synthesis of specific intermediates suitable for the preparation of triazolopyrimidine compounds such as ticagrelor.

专利号:WO-03031376-A1
优先权日:2001-10-12
标 题 :Solid phase synthesis of substituted 1,5-benzodiazepine-2-one and 1,5-benzothiazepine-2-one
发明人：MORTON GEORGE C; SALVINO JOSEPH M; LABAUDINIERE RICHARD F; HERPIN TIMOTHY F
权利人:AVENTIS PHARMA INC; MORTON GEORGE C; SALVINO JOSEPH M; LABAUDINIERE RICHARD F; HERPIN TIMOTHY F
摘要:A solid phase synthetic method for making substituted 1,5-benzodiazepine-2-one or 1,5-benzothiazepine-2-one. The method is useful for synthesis of large numbers of compounds through automated parallel synthesis or combinatorial library generation and is thus important to rapid discovery or new therapeutic agents containing the base structure of 1,5-benzodiazepine-2-one or 1,5-benzothiazepine-2-one.