CAS: 93324-65-3; Pyren-1-Ylmethanamine Hydrochloride

相似化合物

1086-00-6 2595-90-6 24463-15-8

上下游产品

CAS号281660-03-5 2-chloro-N-(pyr... | CAS号129-00-0 芘

📜1-Pyrenecarboxaldehyde Oxime,盐酸 反应生成 1-芘甲胺 盐酸盐
参考文献:Bair,Kenneth W.;Tuttle,Richard L.;Knick,Vincent C.;Cory,Michael;Mckee+,J. Med. Chem.,33,(1990) N,C. 2385-2393
标题:Bair,Kenneth W.;Tuttle,Richard L.;Knick,Vincent C.;Cory,Michael;Mckee+,J. Med. Chem.,33,(1990) N,C. 2385-2393

专利信息

专利号:US-2019292310-A1
优先权日:2018-03-20
标 题:Synthesis of high density molecular dna brushes via organic-phase ring-opening metathesis (co)polymerization
发明人：ZHANG KE; TAN XUYU
权利人:UNIV NORTHEASTERN
摘要:The invention provides novel synthetic methods for oligonucleotide polymerization reactions that separate the deprotection and cleavage step following solid-phase oligonucleotide synthesis into two separate steps, thereby providing fully protected hydrophobic oligonucleotides that can be further manipulated in organic solvents. The disclosed methods enable the synthesis of new structures, such as brush DNA and brush RNA polymers and micellar spherical nucleic acids (SNAs

专利号:US-6140480-A
优先权日:1996-05-15
标题:Nucleoside analogs with polycyclic aromatic groups attached, methods of synthesis and uses therefor
发明人：KOOL ERIC T
权利人:RES CORP TECHNOLOGIES INC
摘要:The present invention provides fluorescent nucleosides carrying polycyclic aromatic hydrocarbons such as anthracene, phenanthrene, pyrene stilbene, tetracene or pentacene. The subject nucleosides may be synthesized using a C-glycosidic bond formation method employing organocadium or organozinc derivatives of the aromatic compounds and coupling with a 1- alpha -chlororibose or deoxyribose synthon. The alpha -anomers of the coupling reaction may be epimerized to the beta -anomers by acid-catalyzed equilibration. The fluorescent nucleosides act as DNA or RNA base analogs and can be incorporated into nucleic acids. Resultant fluorescently tagged nucleic acids are useful as probes for target nucleic acids in tissues, solutions or immobilized on membranes.

专利号:US-11584752-B2
优先权日:2020-09-08
标题 :Method for controlled release using mechanical force
发明人：ROBB MAXWELL J; HU XIAORAN; ZENG TIAN
权利人:CALIFORNIA INST OF TECHN
摘要:A general and modular mechanophore platform that efficiently releases a cargo molecule via a mechanically triggered cascade reaction is described, along with methods of synthesis and use thereof. The mechanophore platform comprises a stable Diels-Alder adduct mechanophore comprising a 2-furylcarbinol derivative as its diene component, wherein the 2-furylcarbinol derivative is, in turn, pre-loaded with a covalently attached cargo molecule, and wherein the Diels-Alder adduct mechanophore is embedded into a polymer chain or polymer network, such that the mechanophore platform undergoes the retro [4+2] cycloaddition reaction under mechanical force to reveal the unstable 2-furylcarbinol derivative, which, in turn, easily decomposes under mild conditions to release its molecule cargo.

专利号:US-6448443-B1
优先权日:1996-10-16
标 题:Synthesis of combinatorial libraries of compounds reminiscent of natural products

专利号:EP-0927188-B1
优先权日:1996-05-15
标题:Novel nucleoside analogs with polycyclic aromatic groups attached, methods of synthesis and uses therefor
发明人：KOOL ERIC T
权利人:UNIV ROCHESTER
摘要:The present invention provides fluorescent nucleosides carrying polycyclic aromatic hydrocarbons such as anthracene, phenanthrene, pyrene, stilbene, tetracene or pentacene. The subject nucleosides may be synthesized using a C-glycosidic bond formation method employing organocadium or organozinc derivatives of the aromatic compounds and coupling with a 1- alpha -chlororibose or deoxyribose synthon. The alpha -anomers of the coupling reaction may be epimerized to the beta -anomers by acid-catalyzed equilibration. The fluorescent nucleosides act as a DNA or RNA base analogs and can be incorporated into nucleic acids. Resultant fluorescently tagged nucleic acids are useful as probes for target nucleic acids in tissues, solutions or immobilized on membranes.

专利号:US-10570157-B2
优先权日:2015-07-30
标 题 :Cyclic diarylboron derivatives as NLRP3 inflammasome inhibitors
发明人：BROUGH DAVID; ALLAN STUART MCRAE; FREEMAN SALLY; BALDWIN ALEX GEORGE
权利人:UNIV MANCHESTER
摘要:Inhibitor compounds are disclosed. The compounds are effective in the treatment of diseases or conditions in which interleukin 1 β activity is implicated. Methods of synthesis of the compounds, as well as pharmaceutical compositions comprising the compounds are also disclosed.