CAS: 701-99-5; 2-Phenoxyacetyl Chloride

上下游产品

CAS号122-59-8 苯氧乙酸 | CAS号108-95-2 苯酚 | CAS号139-02-6 苯酚钠 | CAS号10026-13-8 五氯化磷 | CAS号107637-99-0 1-benzofuran-3-ol | CAS号110522-74-2 2'-脱氧-N6-苯氧基乙酰基腺苷 | CAS号3598-14-9 苯氧基乙腈 | CAS号38678-58-9 2,5-二氧代吡咯烷-1-基 ... | CAS号40665-68-7 (3-苯氧基-2-氧代脯氨酰基... | CAS号142075-23-8 3-hydroxy-1-phe... | CAS号18861-16-0 N-phenethyl-2-p... | CAS号18859-21-7 N-methyl-2-phen... | CAS号18705-01-6 Acetamide,2-phe... | CAS号75-87-6 三氯乙醛

苯氧乙酸置于氯化亚砜体系中,化学反应 4.0H,反应生成 苯氧乙酰氯
参考文献:迈向可溶的5,10-二杂间二甲苯:5,10-二氧杂二甲苯,5,10-二异丁二烯和5,10-二杂氮杂烯的合成和反应性
标题:迈向可溶的5,10-二杂间二甲苯:5,10-二氧杂二甲苯,5,10-二异丁二烯和5,10-二杂氮杂烯的合成和反应性
摘要:以下工作介绍了三种通用方法,这是首次允许合成包含两个相同杂原子(即氧o°C,氮nnc或硫ssc)的5,10-二杂苯并二烯衍生物.所描述的两种途径涉及相应的三烯2的光环化,这是导致七环芳族体系的关键步骤.第三种方法基于茚三酮14与苯并[B]杂油15之间的酸性缩合.还介绍了5,10-二杂甲苯烯核的典型官能化.此外,本文讨论了三种建议的途径来接收特定的5,10-二杂间苯二酚衍生物的优点和局限性,因为到目前为止尚不适合用于获得具有任何类型杂原子分子的通用方法.
DOI:10.1021/acs.Joc.9B03387

专利信息

专利号:US-5204456-A
优先权日:1986-04-08
标题:Derivatives of nucleosides and their use for the synthesis of oligonucleotides
发明人：MOLKO DIDIER; SCHULHOF JEAN-CLAUDE; TEOULE ROBERT
权利人:COMMISSARIAT ENERGIE ATOMIQUE
摘要:The invention relates to derivatives of nucleosides and their use for the synthesis of oligonucleotides. These derivatives are in accordance with the formula: (I) in which B represents a radical derived from guanine, cytosine or adenine, whose exocylic NH group is protected by the group with R1 representing a hydrogen atom or a alkyl radical and R2 a hydrogen atom, and alkyl radical, an alkoxy radical and optionally substituted aryloxy radical, R3 represents a hydrogen atom, the dimethoxytrityl radical or the radical R4 represents a hydrogen atom, the radical of formula: or a radical suitable for the synthesis of polynucelotides and R5 represents a hydrogen atom or the protected or unprotected hydroxyl OH radical.

专利号:US-6951932-B2
优先权日:2001-10-25
标 题:Synthesis of 2-aralkoxyadenosines and 2-alkoxyadenosines
发明人：MOORMAN ALLAN R
权利人:KING PHARMACEUTICALS RES & DEV
摘要:The invention provides new methods for synthesis of 2-aralkyloxyadenosines and 2-alkoxyadenosines. The invention is particularly useful for synthesis of 2-[2-(4-chlorophenyl)ethoxy]adenosine. Preferred methods of the invention include activating a guanosine compound followed by hydrolysis; alkylating the hydrolyzed compound with subsequent animation to provide a 2-aralkyloxyadenosine or a 2-alkoxyadenosine compound.

专利号:US-5300638-A
优先权日:1991-07-31
标题:Asymmetric synthesis of taxol side chain
发明人：FARINA VITTORIO; HAUCK SHEILA I
权利人:BRISTOL MYERS SQUIBB CO
摘要:The present invention relates to a process for the preparation of (3R, 4S)-3-hydroxy-4-phenyl-2-azetidinone derivatives which are useful intermediates in the synthesis of taxol from baccatin III, said process comprises reacting an acyloxyacetyl halide with an imine derived from L-threonine; and to compounds of formula (III) which are produced in said process: ##STR1## wherein Ar is phenyl; R 1 is hydrogen, an acyl radical of a carboxylic acid, or a carbonic acid ester radical; R 2 is hydrogen or a carboxy protecting group; and R 3 is hydrogen or a hydroxy protecting group.

专利号:US-2009306400-A1
优先权日:2006-03-27
标 题:Convergent process for the synthesis of taxane derivatives.
发明人：HENRI JOHN T; MCCHESNEY JAMES D; VENKATARAMAN SYLESH K; LAMB RODGER L; FOSTER JONATHAN E; SUMNER CHRISTIAN M; YE SHANGPING
权利人:HENRI JOHN T; MCCHESNEY JAMES D; VENKATARAMAN SYLESH K; LAMB RODGER L; FOSTER JONATHAN E; SUMNER CHRISTIAN M; YE SHANGPING
摘要:The present invention is broadly directed to novel compounds useful for the synthesis of biologically active compounds, including taxane derivatives, and convergent processes for the preparation of these taxane derivatives and their intermediates.

专利号:US-4264775-A
优先权日:1976-10-27
标 题:Synthesis of β-aminostyrenes
发明人：WHITE WILLIAM A
权利人:LILLY CO ELI
摘要:A simple process for the preparation of beta -aminostyrenes proceeds from anilines by successively diazotizing, reacting with a vinyl ester, and reacting with a secondary amine without purification of the intermediate products. The compounds are reactive enamines useful in organic synthesis.

专利号:US-4369312-A
优先权日:1980-07-04
标 题:Method of producing oxo-containing azetidinone compounds
发明人：HASHIMOTO MASASHI; ARATANI MATSUHIKO; HAGIWARA DAIJIRO; SAWADA KOZO; ONAMI TETSUO
权利人:FUJISAWA PHARMACEUTICAL CO
摘要:This invention relates to a novel method of producing oxo-containing azetidinone compounds, or salts thereof, or hydrates thereof, said compounds having utility as antimicrobial agents and as intermediates for the synthesis of other azetidinone compounds having antimicrobial activity.