CAS: 55648-20-9; Alprostadil Alfadex
该化合物是一种化学化合物,具有各种异丙烯衍生物和环丙二烯化合物的典型特征.这种物质由于其类似亚丙二烯酸结构,很可能具有抗氟性和止痛性,已知在各种生理过程,包括疼痛调控和炎症中起着作用. 氢氧基化合物的存在增强了其溶解性和潜在的再活性,而环丙二烯成分则有助于通过形成宿主-访客综合体来提高活性化合物的稳定性和生物利用率. 环丙二烯是一种循环性亚甲酸盐化合物,可以将其装入生物系统,从而便利其迁移. (11,13E,15S) 说明具体的立体化学学表明一种明确的空间安排,可以影响化合物的溶解溶性和潜在生物循环的化合物, 与该化合物的分解变的特性代表了一种独特的生物反应.
- 英文名称Alprostadil Alfadex
- 中文名称前列地尔 α-环糊精包合物
- IUPAC名称(1S,3R,5R,6S,8R,10R,11S,13R,15R,16S,18R,20R,21S,23R,25R,26S,28R,30R,31R,32R,33R,34R,35R,36R,37R,38R,39R,40R,41R,42R)-5,10,15,20,25,30-hexakis(hydroxymethyl)-2,4,7,9,12,14,17,19,22,24,27,29-dodecaoxaheptacyclo[26.2.2.23,6.28,11.213,16.218,21.223,26]dotetracontane-31,32,33,34,35,36,37,38,39,40,41,42-dodecol;7-[(1R,2R,3R)-3-hydroxy-2-[(E,3S)-3-hydroxyoct-1-enyl]-5-oxocyclopentyl]heptanoic acid
- CAS编号55648-20-9
- MFCD编号:MFCD00165539
- EINECS号:832-043-3
- 分子式:C56H94O35分子量:1327.33
- 产品CID: 2517864
- 产品分类化学试剂 → 有机试剂 → 环糊精
物理性质
MSDS等安全信息
欧盟法规
C&L通报合成工艺路线路线简述
海关参考信息
- 2901210000-乙烯
2901220000-丙烯
2905122000-异丙醇
2905310000-1,2-乙二醇 - 💡 提示：海关信息按照顺序优先匹配，如需确认的海关信息，请参考相关资料。
- 详情请参考：📖 海关编码查询和海关进出口税则
专利信息
专利号:US-11801281-B2
优先权日:2008-10-06
标题:Tissue occluding agent comprising an ieikieikieiki peptide
发明人：TAKAMURA KENTARO; GOJO SATOSHI; KOBAYASHI SATORU
权利人:3 D MATRIX LTD
摘要:There is provided a bioabsorbable peptide tissue occluding agent that can be applied to large mammals including humans, the peptide tissue occluding agent being obtained by artificial synthesis to avoid concerns of infection by viruses and the like. n The tissue occluding agent contains a peptide, wherein the peptide is an amphiphilic peptide having 8-200 amino acid residues with the hydrophilic amino acids and hydrophobic amino acids alternately bonded, and is a self-assembling peptide exhibiting a β-structure in aqueous solution in the presence of physiological pH and/or a cation.
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品牌试剂参考报价(招募中)
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合成参考文献
参考文献:10.1007/s113-002-8159-2
摘要:Slodicka R, Lautenbach M, Eisenschenk A. [Using prostaglandin E1 in microvascular reconstruction of the upper extremity after acute trauma]. Unfallchirurg. 2002 Jan;105(1):14–8. doi: 10.1007/s113-002-8159-2.
参考文献:10.1385/endo:23:2-3:149
摘要:Bella AJ, Brock GB. Intracavernous pharmacotherapy for erectile dysfunction. Endocrine. 2004 Mar;23(2-3):149–55. doi: 10.1385/endo:23:2-3:149.
参考文献:10.1007/s10067-004-0871-1
摘要:Hayakawa I, Sato S, Hasegawa M, Echigo T, Takehara K. A case of scleroderma spectrum disorder with anticentriole antibody and pulmonary hypertension. Clin Rheumatol. 2004 Jun;23(3):266–8. doi: 10.1007/s10067-004-0871-1.
参考文献:10.1007/s12282-015-0651-6
摘要:Shimo A, Tsugawa K, Tsuchiya S, Yoshie R, Tsuchiya K, Uejima T, Kojima Y, Shimo A, Hayami R, Nishikawa T, Yabuki Y, Kawamoto H, Sudo A, Fukuda M, Kanemaki Y, Maeda I. Oncologic outcomes and technical considerations of nipple-sparing mastectomies in breast cancer: experience of 425 cases from a single institution. Breast Cancer. 2016 Nov;23(6):851–60. doi: 10.1007/s12282-015-0651-6.
参考文献:10.1007/s001040050877
摘要:Altstaedt HO. [Experience with the therapy of acute finger ischemia by high-dose intra-arterial infusion of PGE1 through a surgically introduced catheter]. Chirurg. 1999 Oct;70(10):1144–8. doi: 10.1007/s001040050877.
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