CAS: 513-10-0; Ecothiopate Iodide

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CAS号3147-20-4 thiophosphoric ... | CAS号74-88-4 碘甲烷

📜硫代磷酸 O,O'-二乙基 S-(2-二甲基氨基-乙基)酯,碘甲烷 以 乙腈 作为反应溶剂,化学反应 14.5H,以13 Mg的收率获得产物碘依可酯
参考文献:Echothiophate Iodide Process
标题:Echothiophate Iodide Process
摘要:本发明涉及一种制备碘化乙胆碱(i)的过程.通过本发明的方法获得的碘化乙胆碱(i)以新的晶体形式形式-Set命名.根据本发明的碘化乙胆碱(i)制备过程是一种环保的过程,避免使用有害的溶剂体系,并提供高纯度的碘化乙胆碱(i).具有高纯度的碘化乙胆碱(i)晶体形式-Set的药物组合物在治疗青光眼等眼部疾病方面具有用处.

专利信息

专利号:US-6399107-B1
优先权日:1998-12-22
标 题:Use of inhibitors of gag synthesis for the treatment of corneal haze
发明人：KESSLER TIMOTHY L; NIXON JON C; DAVID KAREN C; GRAFF GUSTAV
权利人:ALCON LAB INC
摘要:This invention relates to the compositions and methods for the treatment of corneal haze. The compositions and methods are particularly directed to the use of GAG synthesis inhibitors in the treatment of corneal haze.

专利号:US-5512577-A
优先权日:1994-06-02
标 题:Bicyclic hexahydroaporphine and 1-benzyloctahydroisoquinoline therapeutic compositions and processes for utilizing said compositions
发明人：ROCHE VICTORIA F; OHIA S EDET; ROCHE EDWARD B
权利人:UNIV CREIGHTON
摘要:The invention relates to the method of synthesis of bicyclic hexahydroaporphine compounds which may provide improved therapy for diseases characterized by an increase in intraocular pressure. More specifically, the present invention relates to the preparation of agents which may provide for improved treatment of patients with glaucoma or ocular hypertension. The present invention describes the intraocular pressure lowering capabilities of several of the bicyclic hexahydroaporphine structures.

专利号:US-2007148246-A1
优先权日:2005-08-11
标题:Nucleic Acid-Based Matrixes
发明人：LUO DAN; LI YOUGEN
权利人:LUO DAN; LI YOUGEN
摘要:Various nucleic acid-based matrixes are provided, comprising nucleic acid monomers as building blocks, as well as nucleic acids encoding proteins, so as to produce novel biomaterials. Methods of utilizing such biomaterials include delivery of biologically active agents, cell and tissue culture, and cell-free protein synthesis.

专利号:WO-0037072-A1
优先权日:1998-12-22
标题 :Use of inhibitors of gag synthesis for the treatment of corneal haze

专利号:US-2014315720-A1
优先权日:2012-10-24
标 题 :Polysaccharide ester microspheres and methods and articles relating thereto
发明人：FALLON DENIS G; GARRETT THOMAS S; KIZER LAWTON E; ZAZZARA KAREN L; COMBS MICHAEL T; JOHNSON RICHARD K; DEHART GARY
权利人:CELANESE ACETATE LLC
摘要:A method for producing a polysaccharide ester microsphere may include forming a polysaccharide ester product from a polysaccharide synthesis, wherein the polysaccharide ester product comprises a polysaccharide ester and a solvent; diluting the polysaccharide ester product, thereby yielding a polysaccharide ester dope; and forming a plurality of polysaccharide ester microspheres from the polysaccharide ester dope. Suitable polysaccharides may include, but are not limited to, starch, cellulose, hemicellulose, algenates, chitosan, and any combination thereof. Esters thereof may be organic esters (e.g., acetate and the like), inorganic esters (e.g., sulfonates and the like), or combinations thereof. Further, the solids conent of the polysaccharide ester dope, in some instances, may be greater than about 16 wt %.

专利号:US-2012232031-A1
优先权日:2009-10-19
标 题:Injectable formulations for intra-articular or peri-articular administration
发明人：HUTCHINSON JOHN HOWARD; PRASIT PETPIBOON PEPPI; DEARMOND ISABELLE MARGUERITE
权利人:HUTCHINSON JOHN HOWARD; PRASIT PETPIBOON PEPPI; DEARMOND ISABELLE MARGUERITE; PANMIRA PHARMACEUTICALS LLC
摘要:Described herein are injectable formulations for intra-articular or peri-articular administration, wherein the formulation is administered to treat joint pain. An injectable formulation for intra-articular or peri-articular administration disclosed herein comprises a therapeutically-effective amount of a leukotriene synthesis inhibitor compound formulated for intra-articular or peri-articular administration.