专利号:US-2024327370-A1 优先权日:2021-07-01 标题:Process for the biobased synthesis of schweinfurthins g, k and r 发明人:ROUSSI FANNY; LITAUDON MARC; DESRAT SANDY; JEZEQUEL GWENAËLLE; RAMPAL CÉLINE; PHAM VAN CUONG; DOAN THI MAI HUONG 权利人:CENTRE NAT RECH SCIENT; VAST VIETNAM ACADEMY OF SCIENCE AND TECH 摘要:The present invention relates to a process for preparing at least one schweinfurthin chosen from schweinfurthin G of formula (SW-G), schweinfurthin K of formula (SW-K) and schweinfurthin R of formula (SW-R), characterized in that it comprises a step of using mappain of formula (IV).
专利号:US-10100028-B2 优先权日:2013-09-30 标 题:Synthesis routes for prostaglandins and prostaglandin intermediates using metathesis 发明人:YIANNIKOUROS GEORGE PETROS; KALARITIS PANOS; GAMAGE CHAMINDA PRIYAPUSHPA; AREFYEV DENIS VIKTOROVICH 权利人:IRIX PHARMACEUTICALS INC; PATHEON API SERVICES INC 摘要:Methods of synthesizing prostaglandins, prostaglandin analogs and their synthetic intermediates are described. The methods can comprise metal-catalyzed metathesis reactions. Also provided are synthetic intermediates that can be used in the synthesis of the prostaglandins and prostaglandin analogs.
专利号:US-8476471-B2 优先权日:2009-07-13 标 题 :Synthesis of prostanoids 发明人:YIANNIKOUROS GEORGE PETROS; KALARITIS PANOS; GAMAGE CHAMINDA PRIYAPUSHPA; ABERNATHY STEPHANIE BOSSE 权利人:YIANNIKOUROS GEORGE PETROS; KALARITIS PANOS; GAMAGE CHAMINDA PRIYAPUSHPA; ABERNATHY STEPHANIE BOSSE; IRIX PHARMACEUTICALS INC 摘要:The presently disclosed subject matter provides a method of synthesizing prostaglandins and prostaglandin analogs comprising the ring closing metathesis of compounds of Formula (I). Also provided are novel compounds of Formula (I) and Formula (II). In addition to their use as synthetic intermediates in the presently disclosed methods, compounds of Formula (II) can be used as prostaglandin and/or prostaglandin analog prodrugs.
专利号:US-8193307-B2 优先权日:2007-07-23 标题 :Synthesis of photoresist polymer 发明人:TAKEDA TAKANOBU; WATANABE TAMOTSU 权利人:TAKEDA TAKANOBU; WATANABE TAMOTSU; SHINETSU CHEMICAL CO 摘要:A polymer for use in photoresist compositions is synthesized by effecting polymerization reaction to form a polymerization product mixture and subjecting the mixture to molecular weight fractionation by a liquid phase separation technique using a good solvent and a poor solvent. The fractionation step is iterated at least twice, and one iteration of fractionation includes adding a good solvent which is different from the good solvent added in the other iteration of fractionation.
专利号:US-5446062-A 优先权日:1993-11-12 标 题:((4-alkoxypyran-4-yl) substituted) ether, arylalkyl-, arylalkenyl-, and arylalkynyl)urea inhibitors of 5-lipoxygenase 发明人:DELLARIA JOSEPH F; BASHA ANWER; BLACK LAWRENCE A; CHERNESKY LINDA J; LEE WENDY 权利人:ABBOTT LAB 摘要:Compounds of the structure where W is selected from where Q is oxygen or sulfur, R6 and R7 are hydrogen or alkyl, or R6 and R7, together with the nitrogen atoms to which they are attached, define a radical of formula Z is -CH2-, oxygen, sulfur, or -NR9, L1 and L2 are selected from a valence bond, alkylene, propenylene, and propynylene; R1 and R2 are independently selected from alkyl, alkoxy, haloalkyl, halogen, cyano, amino, alkoxycarbonyl, and dialkylaminocarbonyl; Y is selected from oxygen, >NR10, and L3 is selected from alkylene of one to three carbon atoms, propenylene, propynylene, and R3, R4, and R5 are hydrogen or alkyl of one to four carbon atoms inhibit the synthesis of leukotrienes. These compounds are useful in the treatment or amelioration of allergic and inflammatory disease states.
专利号:US-7309799-B2 优先权日:2004-06-01 标 题:Methods for the synthesis of milnacipran and congeners thereof 发明人:BUCHWALD STEPHEN L; SWAGER TIMOTHY M; RARIY ROMAN V 权利人:COLLEGIUM PHARMACEUTICAL INC 摘要:One aspect of the present invention relates to methods for synthesizing milnacipran or congeners thereof. Another aspect of the present invention relates to asymmetric methods for synthesizing enantiomerically enriched milnacipran or congeners thereof. The present invention also relates to methods for synthesizing intermediates useful in the non-asymmetric or asymmetric methods for synthesizing enantiomerically enriched milnacipran or congeners thereof.