专利号:US-2023097824-A1 优先权日:2020-05-08 标 题:Semi-synthesis and use of racemic hematoxylin 发明人:DURRANT EDWARD E; HEINDL DIETER; HUBER FLORIAN MAURITIUS ERASUMU; KLEIN ERIC; KOSMEDER II JEROME W; VOSS EDGAR 权利人:VENTANA MED SYST INC; ROCHE DIAGNOSTICS OPERATIONS INC 摘要:A racemic hematoxylin formulation is disclosed that includes one or both of a stabilizer compound and an antioxidant. The disclosed composition exhibits sufficient stability to be utilized in an automated staining process. Methods of using and making the stabilized composition also are disclosed.
专利号:US-10772990-B2 优先权日:2014-04-01 标题 :Tissue filler compositions and methods of use 发明人:NIKOLIS ANDREAS; HERBERT LISE 权利人:KLOX TECH INC 摘要:The present disclosure relates to methods for stimulating collagen synthesis, cosmetic enhancement of soft tissue and/or inhibiting or treating scarring comprising administering a composition to an area to be treated within a soft tissue, wherein the composition comprises a tissue filler medium and a fluorophore; and illuminating the area with light having a wavelength which can be absorbed by the fluorophore.
专利号:US-2003186237-A1 优先权日:2001-02-14 标题:Methods and compositions of amplifying RNA 发明人:GINSBERG STEPHEN D; CHE SHAOLI 权利人:BAYLOR COLLEGE MEDICINE 摘要:The present invention pertains to a method that will increase the efficiency of second strand cDNA synthesis through a mechanism of “terminal continuationâ€? before further RNA amplification by RNA transcription using, for example, a bacteriophage promoter. In a specific embodiment, a transcription promoter is attached to the 5′ region of cDNA through the same mechanism of “terminal continuationâ€?. Genetic signals are subsequently amplified in a linear manner through RNA transcription. In specific embodiments, the orientation of the transcribed RNA is either sense or antisense, depending on the desired downstream application. In other embodiments, the present invention pertains to methods for extraction and amplification of RNA, particularly mRNA, from histologically stained tissues and cells.
专利号:US-6984734-B2 优先权日:2002-02-26 标 题 :Cyclo[n]pyrroles and methods thereto 发明人:SESSLER JONATHAN L; SEIDEL DANIEL; BOLZE FREDERIC R; KOEHLER THOMAS 权利人:UNIV TEXAS 摘要:The present invention provides an oxidative coupling procedure that allows efficient synthesis of novel cyclo[n]pyrrole macrocycles. Therefore, the present invention provides cyclo[n]pyrroles where n is 6, 7, 8, 9, 10, 11, or 12, and derivatives, multimers, isomers, and ion and neutral molecule complexes thereof as new compositions of matter. A protonated form of cyclo[n]pyrrole displays a gap of up to 700 nm between strong Soret and Q-like absorption bands in the electronic spectrum, demonstrating no significant ground state absorption in the visible portion of the electronic spectrum. Uses of cyclo[n]pyrroles as separation media, nonlinear optical materials, information storage media and infrared filters are provided.
专利号:WO-2021224361-A2 优先权日:2020-05-08 标题 :Semi-synthesis and use of racemic hematoxylin
专利号:CN-115612114-A 优先权日:2021-07-14 标 题:Method and application of copolymer film and its enzymatic self-assembly synthesis
参考文献:10.1007/s11356-021-15502-0 摘要:do Nascimento GE, de Freitas RA, Rodríguez-Díaz JM, da Silva PM, Napoleão TH, Duarte MMMB. Degradation of the residual textile mixture cetyltrimethylammonium bromide/remazol yellow gold RNL-150%/reactive blue BF-5G: evaluation photo-peroxidation and photo-Fenton processes in LED and UV-C photoreactors. Environmental Science and Pollution Research. 2021 Jul 27;28(45):64630–41. doi: 10.1007/s11356-021-15502-0.