CAS: 32267-39-3; 2,6-Diamino-3,6-Dihydropyrimidine-4,5-Dione

专利信息

专利号:US-5350851-A
优先权日:1992-03-16
标题 :Intermediates and a process for synthesis of tetrahydropteridine C6-stereoisomers, including (6S)-tetrahydrofolate and N5-formyl-(6S)-tetrahydrofolate
发明人：BAILEY STEVEN W; AYLING JUNE E
权利人:UNIV SOUTH ALABAMA
摘要:Intermediates and a process for the synthesis of 6-monosubstituted tetrahydropteridine C6-stereoisomers, including (6S)-tetrahydrofolic acid. The intermediates are shown in their two enantiomeric forms as follows: ##STR1## wherein R 1 and R 2 are the same or different and represent hydrogen, methyl, hydroxy, amino, alkyl or dialkylamino, alkoxy, benzyloxy, or benzylthio; R 3 represents an alkene, alkyne, cycloalkyl, benzyl, alkyl (substituted with hydroxy, acetoxy, benzyloxy, alkoxy, alkylthio, amino, carboxy, oxo, or phosphate), a protected aldehyde, or ##STR2## wherein n=1 or 2, R 4 is hydrogen, formyl, methyl, or propargyl, and ZZ represents an amino acid or amino acid polymer.

专利号:US-5401844-A
优先权日:1983-04-11
标 题 :Regulation of enzymes which utilize tetrahydrobiopterin or tetrahydrofolate cofactors with 6,6-disubstituted-tetrahydropteridines
发明人：AYLING JUNE E; BAILEY STEVEN W
权利人:UNIV SOUTH ALABAMA
摘要:6-[2'-Amino-2',2'-disubstituted-ethylamino]-pyrimidines of the structure: ##STR1## in which X=H, NH 2 or NO 2 , which are novel intermediates in the synthesis of quinoid 6,6-disubstituted-dihydro- and 6,6-disubstituted-tetrahydro-pteridines, are claimed.

专利号:US-2010008874-A1
优先权日:2006-04-11
标 题:Substituted pyrimidines, process for their production and their use as effective absorbents of uv irradiation
发明人：CLAES ENK DAVID; SREBNIK MORRIS
权利人:YISSUM RES DEV CO
摘要:The present invention discloses substituted pyrimidines, processes for their synthesis and their use as effective sun-protecting agents either alone or in combination with other known sun-protecting agents.

专利号:WO-9319069-A1
优先权日:1992-03-16
标题:Intermediates and a process for synthesis of tetrahydropteridine c6-stereoisomers, including (6s)-tetrahydrofolate and n5-formyl-(6s)-tetrhydrofolate

专利号:EP-0631581-A1
优先权日:1992-03-16
标题 :Intermediates and a process for synthesis of tetrahydropteridine c6-stereoisomers, including (6s)-tetrahydrofolate and n5-formyl-(6s)-tetrhydrofolate

专利号:AU-3804193-A
优先权日:1992-03-16
标 题:Intermediates and a process for synthesis of tetrahydropteridine C6-stereoisomers, including (6S)-tetrahydrofolate and N5-formyl-(6S)-tetrhydrofolate