CAS: 269396-55-6; (3R)-3-Amino-4-(3,4-Dichlorophenyl)Butanoic Acid,Hydrochloride
该化合物是一种化学化合物,具有独特的结构特征,包括氨基氨基化合物和二氯代苯混合物,典型的化合物具有氨基酸的特性,如由于氨基和氨基酸碳酸功能组的存在而形成氢结的能力,二氯代苯的分体会助长其疏水特性,影响其溶解性和再活性.(R)指定的立体化学显示原子的具体空间安排,可显著影响该化合物的生物活动和与其他分子的相互作用.该化合物可能对制药研究,特别是针对特定生物路径的药物的开发感兴趣.其合成和定性将涉及标准的有机化学技术,其生物系统中的行为将需要进一步调查,以了解其潜在应用和行动机制.
- 英文名称(3R)-3-Amino-4-(3,4-Dichlorophenyl)Butanoic Acid,Hydrochloride
- 中文名称(R)-3-氨基-4-(3,4-二氯苯基)-丁酸盐酸盐
- 其它别名3,4-DICHLORO-D-BETA-HOMOPHENYLALANINE HYDR°CHLORIDE; H-D-BETA-HOPHE(3,4-DICL)-OH HCL; H-D-PHE(3,4-CL 2)-(C*CH2)OH HCL; D-BETA-HOMO(3,4-DICHLOROPHENYL)ALANINE HYDR°CHLORIDE; (R)-3-AMINO-4-(3,4-DICHLOROPHENYL)BUTANOIC ACID HYDR°CHLORIDE; (R)-3-AMINO-4-(3,4-DICHLORO-PHENYL)-BUTYRIC ACID HCL; (R)-3-AMINO-4-(3,4-DICHLOROPHENYL)BUTYRIC ACID HYDR°CHLORIDE
- CAS编号269396-55-6
- MFCD编号:MFCD01860948
- 分子式:C10H11Cl2NO2分子量:248.11
- 产品CID: 1248932
- 产品分类生物化工 → 氨基酸及其衍生物 → 氨基酸盐
物理性质
MSDS等安全信息
合成工艺路线路线简述
海关参考信息
- 2902600000-乙苯
2905121000-正丙醇
2905130000-正丁醇
2912110000-甲醛 - 💡 提示：海关信息按照顺序优先匹配，如需确认的海关信息，请参考相关资料。
- 详情请参考：📖 海关编码查询和海关进出口税则
专利信息
专利号:US-2022243244-A1
优先权日:2019-10-10
标 题 :Compositions and methods for in vivo synthesis of unnatural polypeptides
发明人：ROMESBERG FLOYD E; FISCHER EMIL C; HASHIMOTO KOJI; FELDMAN AARON W; DIEN VIVIAN T; ZHANG YORKE
权利人:SCRIPPS RESEARCH INST
摘要:Disclosed herein are compositions, methods, and kits for a cell incorporating unnatural amino acids into an unnatural polypeptide. Also disclosed herein are compositions, methods, and kits for increasing activity and yield of the unnatural polypeptide synthesized by the cell.
专利号:US-2023037284-A9
优先权日:2018-11-30
标题:Combination therapy of peptidomimetic macrocycles
发明人：GUERLAVAIS VINCENT; ANNIS DAVID ALLEN
权利人:AILERON THERAPEUTICS INC
摘要:The present disclosure describes the synthesis of peptidomimetic macrocycles and methods of using peptidomimetic macrocycles to treat a condition. The present disclosure also describes methods of using peptidomimetic macrocycles in combination with at least one additional pharmaceutically-active agent for the treatment of a condition, for example, cancer.
专利号:US-2025084410-A1
优先权日:2015-01-12
标 题:Incorporation of unnatural nucleotides and methods thereof
发明人：PTACIN JEROD; MALYSHEV DENIS A; CAFFARO CAROLINA E
权利人:SYNTHORX INC
摘要:Disclosed herein are methods, compositions and kits for the synthesis of proteins which comprises unnatural amino acids that utilize a mutant tRNA.
专利号:US-2018371021-A1
优先权日:2017-05-11
标 题 :Peptidomimetic macrocycles and uses thereof
发明人：AIVADO MANUEL; GUERLAVAIS VINCENT; OLSON KAREN
权利人:AILERON THERAPEUTICS INC
摘要:The present disclosure describes the synthesis of peptidomimetic macrocycles and methods of using peptidomimetic macrocycles to treat a condition. The present disclosure also describes methods of using peptidomimetic macrocycles in combination with at least one additional pharmaceutically-active agent for the treatment of a condition, for example, cancer.
专利号:WO-2021072167-A1
优先权日:2019-10-10
标 题:Compositions and methods for in vivo synthesis of unnatural polypeptides
专利号:US-11091522-B2
优先权日:2018-07-23
标题 :Peptidomimetic macrocycles and uses thereof
发明人：AIVADO MANUEL; GUERLAVAIS VINCENT; OLSON KAREN; ANNIS DAVID ALLEN
权利人:AILERON THERAPEUTICS INC
摘要:The present disclosure describes the synthesis of peptidomimetic macrocycles and methods of using peptidomimetic macrocycles to treat a condition. The present disclosure also describes methods of using peptidomimetic macrocycles in combination with at least one additional pharmaceutically-active agent for the treatment of a condition, for example, cancer.
