CAS: 2450-26-2; 4-Hydroxy-3-Methoxy-2-Nitrobenzaldehyde

上下游产品

CAS号2698-69-3 4-甲酰基-2-甲氧基-3-硝基乙酸苯酯 | CAS号881-68-5 乙酰香兰素 | CAS号121-33-5 香草醛 | CAS号7697-37-2 硝酸 | CAS号3066-90-8 2,3-二甲氧基-5-甲基-1... | CAS号605-94-7 2,3-二甲氧基-5-甲基-1,4-苯醌 | CAS号2432-60-2 3-methoxy-2-nit... | CAS号2450-27-3 4-(苄氧基)-3-甲氧基-2... | CAS号6665-98-1 3-硝基邻苯二酚 | CAS号101724-22-5 8-hydroxy-1H-qu... | CAS号3584-32-5 4-苄氧基-3-甲氧基-2-硝基苯甲酸 | CAS号125708-66-9 3-氨基-2-甲氧基苯酚 | CAS号67394-73-4 3,4-dimethoxybe... | CAS号677335-32-9 4-Hydroxy-3-met...

📜Alkaline Earth Salt Of/the/ Methylsulfuric Acid 反应生成4-羟基-3-甲氧基-2-硝基苯甲醛
参考文献:Raiford; Stoesser,Journal Of The American Chemical Society,1928,Vol. 50,P. 2561
标题:Raiford; Stoesser,Journal Of The American Chemical Society,1928,Vol. 50,P. 2561

专利信息

专利号:US-9440940-B2
优先权日:2014-03-18
标 题:Methods for synthesis of psoralen derivatives
发明人：REFOUVELET BERNARD
权利人:MACOPHARMA S A S
摘要:Methods for the synthesis of psoralen derivatives are provided. In one embodiment, the method may include acetylating a compound of formula (II) to form a compound of formula (III), subjecting the compound of formula (III) to a Fries rearrangement to form a compound of formula (IV), and subjecting the compound of formula (IV) to cyclization, reduction and aromatization, to form a compound having the following formula (I):

专利号:US-10494372-B2
优先权日:2014-11-07
标 题 :Synthesis of copanlisib and its dihydrochloride salt
发明人：PETERS JAN-GEORG; RUBENBAUER PHILIPP; GÖTZ DANIEL; GROSSBACH DANJA; MAIS FRANZ-JOSEF; SCHIRMER HEIKO; STIEHL JUERGEN; LOVIS KAI; LENDER ANDREAS; SEYFRIED MARTIN; ZWEIFEL THEODOR; MARTY MAURUS; WEINGÄRTNER GÃœNTER
权利人:Bayer Pharma AG
摘要:The present invention relates to a novel method of preparing copanlisib, copanlisib dihydrochloride, or hydrates of copanlisib dihydrochloride, to novel intermediate compounds, and to the use of said novel intermediate compounds for the preparation of said copanlisib, copanlisib dihydrochloride, or hydrates of copanlisib dihydrochloride. The present invention also relates to copanlisib dihydrochloride hydrates as compounds.

专利号:US-10035803-B2
优先权日:2014-11-07
标 题:Synthesis of copanlisib and its dihydrochloride salt
发明人：PETERS JAN-GEORG; STIEHL JÃœRGEN; LOVIS KAI
权利人:Bayer Pharma AG
摘要:The present invention relates to a novel method of preparing copanlisib, and copanlisib dihydrochloride, to novel intermediate compounds, and to the use of said novel intermediate compounds for the preparation of said copanlisib.

专利号:WO-2016071380-A1
优先权日:2014-11-07
标题 :Synthesis of pi3k inhibitor and salts thereof
发明人：PETERS JAN-GEROG; RUBENBAUER PHILIPP; PLATZEK JOHANNES; STIEHL JUERGEN; LOVIS KAI; SEYFRIED MARTIN; ZWEIFEL THEODOR; MARTY MAURUS; WEINGÄRTNER GÃœNTER
权利人:Bayer Pharma AG
摘要:The present invention relates to a novel method of preparing a compound of formula (I) or salt thereof, to novel intermediate compounds, to the use of said novel intermediate compounds for the preparation of said compound of formula (I) or salt thereof and to a method of purifying a compound of formula (I), or salt thereof. The present invention also relates to crystalline forms, form A, of a compound of formula (I), pharmaceuticals and uses thereof.

专利号:WO-2016071382-A1
优先权日:2014-11-07
标题:Synthesis of pi3k inhibitor and salts thereof
发明人：PETERS JAN-GEORG; RUBENBAUER PHILIPP; LOVIS KAI; STIEHL JUERGEN; SEYFRIED MARTIN; ZWEIFEL THEODOR; MARTY MAURUS; WEINGÄRTNER GÃœNTER
权利人:Bayer Pharma AG
摘要:The present invention relates to a novel method of preparing a compound of formula (I) or salt thereof, to novel intermediate compounds, to the use of said novel intermediate compounds for the preparation of said compound of formula (I) or salt thereof. The present invention also relates to crystalline forms, form A, of a compound of formula (I), pharmaceuticals and uses thereof.

专利号:TW-I697494-B
优先权日:2014-11-07
标 题:Synthesis of copanlisib and its dihydrochloride salt