CAS: 137339-65-2; Sfllrnpndkyepf
该化合物是由氨基酸的具体序列组成的酸.这种酸具有极地,非极地和充电残留物的组合,有助于其独特的特性和生物功能.氨基硫酸的存在,如硅,苯丙氨,,素,氨酸,碱,盐,酸,赖氨酸和谷酸等,表明它可能在各种生理过程中发挥作用,可能包括在蛋白质中的信号路径或结构功能.该序列表明它有可能与其他生物分子相互作用,受到成份氨酸的侧链的影响.此外,酸的溶性,稳定性和再活性可能受到其长度和组成的影响,使其在生物化学,药理学和生物技术等领域引起兴趣.有必要开展进一步的研究,以阐明其具体的生物活动和潜在应用.
- 英文名称Sfllrnpndkyepf
- 中文名称凝血酶受体兴奋剂
- 其它别名SFLLRNPNDKYEPF; SFLLRNPNDKYEPF, HUMAN THROMBIN RECEPTOR 42-55; SER-PHE-LEU-LEU-ARG-ASN-PRO-ASN-ASP-LYS-TYR-GLU-PRO-PHE; THROMBIN RECEPTOR ACTIVATOR; THROMBIN RECEPTOR (42-55), HUMAN; THROMBIN RECEPTOR AGONIST; THROMBIN RECEPTOR AGONIST PEPTIDE; TRAP
- CAS编号137339-65-2
- MFCD编号:MFCD00133815
- 分子式:C81H118N20O23分子量:1739.92
- 产品CID: 580520
- 产品分类生物化工 → 多肽
物理性质
MSDS等安全信息
- 警示词warning
- 危险描述H303May be harmful if swallowed+H313Skin contact may be harmful+H333Inhalation may be harmful to the body
- 防范说明P264Thoroughly clean after treatmentP280Wear protective gloves/Wear protective clothing/Wear protective goggles/Wear a protective maskP305If it enters the eyesP351Rinse carefully with water for a few minutesP338Remove the contact lens(If any)And easy to operate,Continue flushingP337If eye irritation persistsP313Obtain medical advice/care
- UN编号NONH for all modes of transport
- 危险品标志T
- 安全声明53-45
- 危险类别码61
- WGK Germany3.0
上下游产品
1-(tert-butoxycarbonyl)-L-proline N-tert-butoxycarbonyl-L-phenylalanineN-tert-butoxycarbonyl-L-phenylalanine B°C-Asp(O-cyclohexyl)-OH N-α-tert-butyloxycarbonyl-glutamic acid, γ-cyclohexyl ester合成工艺路线路线简述
海关参考信息
- 2902600000-乙苯
2905121000-正丙醇
2905130000-正丁醇
2912110000-甲醛 - 💡 提示：海关信息按照顺序优先匹配，如需确认的海关信息，请参考相关资料。
- 详情请参考：📖 海关编码查询和海关进出口税则
专利信息
专利号:US-5859191-A
优先权日:1996-12-05
标 题:Method for the site-specific modification of peptide alpha amines
发明人：MILLER STEPHEN; SCANLAN THOMAS S
权利人:UNIV CALIFORNIA
摘要:A peptide comprising a free terminal alpha amine is treated with an aryl sulfonamide activating agent, resulting in an activated amide. The resulting activated amide is deprotonated with a base and modified by the addition of a substituent group. The aryl sulfonamide activating group is cleaved using a nucleophilic substitution reaction. The method is particularly useful for the modification of peptides at specific N-alpha positions, and is compatible with conventional solid phase peptide synthesis, including those that utilize Fmoc protecting groups.
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品牌试剂参考报价(招募中)
📌 第三方产品分析报告
合成参考文献
参考文献:10.1097/00005344-199310000-00015
摘要:Ku DD, Zaleski JK. Receptor Mechanism of Thrombin-Induced Endothelium-Dependent and Endothelium-Independent Coronary Vascular Effects in Dogs. Journal of Cardiovascular Pharmacology. 1993 Oct;22(4):609–76. doi: 10.1097/00005344-199310000-00015.
参考文献:10.1016/s0021-9258(17)37225-3
摘要:Mari B, Imbert V, Belhacene N, Far DF, Peyron JF, Pouysségur J, Van Obberghen-Schilling E, Rossi B, Auberger P. Thrombin and thrombin receptor agonist peptide induce early events of T cell activation and synergize with TCR cross-linking for CD69 expression and interleukin 2 production. Journal of Biological Chemistry. 1994 Mar;269(11):8517–23. doi: 10.1016/s0021-9258(17)37225-3.
参考文献:10.1016/s0021-9258(17)36738-8
摘要:Shankar R, de la Motte CA, Poptic EJ, DiCorleto PE. Thrombin receptor-activating peptides differentially stimulate platelet-derived growth factor production, monocytic cell adhesion, and E-selectin expression in human umbilical vein endothelial cells. Journal of Biological Chemistry. 1994 May;269(19):13936–41. doi: 10.1016/s0021-9258(17)36738-8.
参考文献:10.1016/0014-2999(94)90613-0
摘要:Antonaccio MJ, Normandin D. Role of Ca2+ in the vascular contraction caused by a thrombin receptor activating peptide. Eur J Pharmacol. 1994 Apr 11;256(1):37–44. doi: 10.1016/0014-2999(94)90613-0.
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