CAS: 1195-09-1; 2-Methoxy-5-Methylphenol

该化合物是有机化合物,其特征是附于甲苯骨的氢氧基(-OH)和甲氧基(-OCH)组;该化合物一般是无色的,其纯度和形态取决于黄色液体或固态;有机溶剂中可溶解,且因氢氧基组而表现出中等极性;氢氧和甲氧基组的存在,其作为苯丙酸化合物的潜力有所增强,可展示抗氧化剂特性. 3-Hydroxy-4-methoxytolune由于有可能在合成中应用,并作为较复杂的化学结构的前体,因此在各个领域,包括制药和材料科学领域都有兴趣.此外,其再活性可能受到芳香环上的亚成成分的影响,因此它将成为进一步修改化学品的宝贵化合物.在处理和储存时,应参考安全数据,因为任何化学物质都存在.

结构式图片

相似化合物

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合成工艺路线路线简述

  • 合成目标产物 2-Methoxy-5-Methylphenol 主要起始原料 Isovanillin
  • (文献来源)合成步骤主要原料 Isovanillin
📜对甲苯甲醚置于spiro[bicyclo[2.2.1]Heptane-2,4'-[1,2]Dioxolane]-3',5'-Dione,甲胺体系中,用 乙醇 用作溶剂,化学反应 24.0H,以55%的收率获得2-甲氧基-5-甲基苯酚
参考文献:调节过氧酸酐对芳烃ch键氧化的反应性
标题:调节过氧酸酐对芳烃ch键氧化的反应性
摘要:从聚合物到药物,许多化学研究领域中的酚部分都是关键的结构基序.在此,我们报告了结构上苛刻的环状过氧化物(螺[双环[2.2.1]庚烷-2,4'-[1,2]二氧戊环]-3',5'-二酮,P4)的设计和使用.芳族底物的直接羟基化.新的过氧化物具有高的热稳定性,可以由容易获得的起始原料合成.使用p4进行的芳族ch氧化通常显示出非常好的收率(高达96%)和可观的区域选择性.
Doi:10.1021/acs.Joc.8B01392

海关参考信息

专利信息


专利号:US-11384367-B2
优先权日:2016-12-22
标题:Synthesis of bioproducts from lignin-derived aromatics by genetically modified microorganisms
发明人:GLADDEN JOHN M; SKERKER JEFFREY M; KEASLING JAY D; KIRBY JAMES; YAEGASHI JUNKO
权利人:UNIV CALIFORNIA; NAT TECH & ENG SOLUTIONS SANDIA LLC; BATTELLE MEMORIAL INSTITUTE FOR MANAGEMENT AND OPERATION OF PACIFIC NORTHWEST NAT LABORATORY; NATIONAL TECH AND ENGINEERING SOLUTIONS OF SANDIA LLC
摘要:The present invention provides for a method of converting a depolymerized lignin aromatic compound into a bioproduct, comprising: (a) providing a composition comprising a depolymerized lignin aromatic compound, optionally a depolymerized cellulose, and optionally a depolymerized hemicellulose, and (b) introducing a genetically modified microorganism to the composition, wherein the genetically modified microorganism is capable of converting the depolymerized lignin aromatic compound into a bioproduct; such that the depolymerized lignin aromatic compound is converted into a bioproduct.

专利号:US-6245937-B1
优先权日:1996-11-29
标题 :Liquid phase parallel synthesis of chemical libraries
发明人:CHENG SOAN; SAUNDERS JOHN
权利人:DUPONT PHARMACEUTICALS RES LAB
摘要:This invention features methods of biphasic synthesis for synthesizing combinatorial libraries and combinatorial libraries of chemical compounds utilizing the template, and combinatorial libraries of chemical compounds formed by the methods of this invention.

专利号:US-8653282-B2
优先权日:2007-10-18
标 题:Preparation of dihydrothieno [3,2-D] pyrimidines and intermediates used therein
发明人:FRUTOS ROGELIO; KRISHNAMURTHY DHILEEPKUMAR; MULDER JASON ALAN; RODRIGUEZ SONIA; SENANAYAKE CHRIS HUGH; TAMPONE THOMAS G
权利人:FRUTOS ROGELIO; KRISHNAMURTHY DHILEEPKUMAR; MULDER JASON ALAN; RODRIGUEZ SONIA; SENANAYAKE CHRIS HUGH; TAMPONE THOMAS G; BOEHRINGER INGELHEIM INT
摘要:The invention relates to improved methods of preparing dihydrothienopyrimidines of formula 1, and intermediates thereof, (I) wherein X is SO or SO 2 , preferably SO, and wherein R A , R 1 , R 2 , R 3 , R 4 and R 5 have the meanings given in the description. The methods according to this invention are more suitable for large-scale synthesis of said compounds than prior methods because the new synthetic process avoids distillation and chromatographic purification between steps and results in a higher overall yield of the desired product.

专利号:US-9765044-B2
优先权日:2013-03-15
标 题 :Synthesis of novel ionic liquids from lignin-derived compounds
发明人:SOCHA AARON; SINGH SEEMA; SIMMONS BLAKE A; BERGERON MAXIME
权利人:UNIV CALIFORNIA; SANDIA CORP
摘要:Methods and compositions are provided for synthesizing ionic liquids from lignin derived compounds comprising: contacting a starting material comprising lignin with a depolymerization agent to depolymerize the lignin and form a mixture of aldehyde containing compounds; contacting the mixture of aldehyde containing compounds with an amine under conditions suitable to convert the mixture of aldehyde containing compounds to a mixture of amine containing compounds; and contacting the mixture of amine containing compounds with an acid under conditions suitable to form an ammonium salt, thereby preparing the ionic liquid.

专利号:US-9388345-B2
优先权日:2012-07-03
标题:Hydrocarbon synthesis methods, apparatus, and systems
发明人:MCNEFF CLAYTON V; MCNEFF LARRY C; NOWLAN DANIEL THOMAS; YAN BINGWEN; GREUEL PETER G
权利人:SARTEC CORP
摘要:Embodiments of the invention include apparatus and systems for hydrocarbon synthesis and methods regarding the same. In an embodiment, the invention includes a process for creating a hydrocarbon product stream comprising reacting a reaction mixture in the presence of a catalyst inside of a reaction vessel to form a product mixture, the reaction mixture comprising a carbon source and water. The temperature inside the reaction vessel can be between 450 degrees Celsius and 600 degrees Celsius and the pressure inside the reaction vessel can be above supercritical pressure for water. In an embodiment, the invention includes an extrusion reactor system for creating a hydrocarbon product stream. The temperature inside the extrusion reactor housing between 450 degrees Celsius and 600 degrees Celsius. Pressure inside the reaction vessel can be above supercritical pressure for water. Other embodiments are also included herein.

专利号:US-2002048774-A1
优先权日:1996-11-29
标题 :Liquid phase parallel synthesis of chemical libraries

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品牌试剂参考报价(招募中)

📌 第三方产品分析报告

✅ COA系统入驻 | 共享模式

主要参考文献

参考标题:Organophotocatalytic Aerobic Oxygenation Of Phenols In A Visible‐light Continuous‐flow Photoreactor
作者:Joël Wellauer,Dragan Miladinov,Thomas Buchholz,Jan Schütz,René T. Stemmler,Jonathan A. Medlock,Werner Bonrath,Christof Sparr |发布日期:2021.7.7
摘要:A Mild Photocatalytic Phenol Oxygenation Enabled By A Continuous-Flow Photoreactor Using Visible Light And Pressurized Air Is Described Herein. Products For Wide-Ranging Applications, Including The Synthesis Of Vitamins, Were Obtained In High Yields By Precisely Controlling Principal Process Parameters. The Reactor Design Permits Low Organophotocatalyst Loadings To Generate Singlet Oxygen. It Is Anticipated

合成参考文献


摘要:Barsegyan, Y. A.; Vil’, V. A.; Tomkinson, N. C. O.; Terent’ev, A. O., Science of Synthesis Knowledge Updates, (2022) 1, 239.
摘要:J. Sunkel and H. Staude, Ber. Bunsenges. Physik. Chem. 72, 567 (1968).
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