CAS: 1073354-18-3; 1-Isopropyl-4-(4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-yl)Phenyl)Piperazine
- 英文名称1-Isopropyl-4-(4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-yl)Phenyl)Piperazine
- 中文名称1-异丙基-4-(4-(4,4,5,5-四甲基-1,3,2-二氧硼硼烷-2-基)苯基)哌嗪
- IUPAC名称1-propan-2-yl-4-[4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]piperazine
- 其它别名4-(4-异丙基哌嗪)苯硼酸频那醇酯; 4-(4-Isopropylpiperizinyl)Phenylboronic Acid, Pinacol Ester
- CAS编号1073354-18-3
- MFCD编号:MFCD06795656
- EINECS号:691-423-5
- 分子式:C19H31BN2O2分子量:330.27
- 产品CID: 112074
- 产品分类有机原料→分子砌块→芳环类化合物→苯类化合物
相似化合物
1003043-01-3 656257-45-3 747413-21-4物理性质
MSDS等安全信息
欧盟法规
C&L通报合成工艺路线路线简述
- 合成目标产物 4-(4-Isopropylpiperizinyl)Phenylboronic Acid, Pinacol Ester 主要起始原料 Bis(Pinacolato)Diboron And 1-(4-Bromo-Phenyl)-4-Isopropyl-Piperazine
- (文献来源)合成步骤主要原料 Bis(Pinacolato)Diboron 和 1-(4-Bromo-Phenyl)-4-Isopropyl-Piperazine
📜1-(4-溴苯基)哌嗪置于1,1'-双(二苯膦基)二茂铁二氯化钯(II)二氯甲烷复合物,Potassium Acetate,三乙酰氧基硼氢化钠体系中,用 二氯甲烷,甲苯 用作溶剂,化学反应 27.0H,反应生成4-(4-异丙基哌嗪)苯硼酸频那醇酯
参考文献: Halo-Substituted Amino Pyridine Compounds As Inhibitors Of The Haematopoietic Progenitor Kinase 1 (Hpk1)[fr] Composés D'Amino Pyridine Halo-Substitués Utilisés En Tant Qu'Inhibiteurs De La Kinase Des Progéniteurs Hématopoïétiques 1 (Hpk1)
标题: Halo-Substituted Amino Pyridine Compounds As Inhibitors Of The Haematopoietic Progenitor Kinase 1 (Hpk1)[fr] Composés D'Amino Pyridine Halo-Substitués Utilisés En Tant Qu'Inhibiteurs De La Kinase Des Progéniteurs Hématopoïétiques 1 (Hpk1)
摘要:本申请涉及公式(i)的卤代杂环化合物或其药学上可接受的盐,溶剂或前药,以及包含这些化合物或药学上可接受的盐,溶剂或前药的组合物,以及在治疗可通过抑制hpk1来治疗的疾病,紊乱或情况方面的各种用途,例如癌症.
专利信息
专利号:US-11066447-B2
优先权日:2016-08-08
标 题:Aureobasidium derivatives and methods of synthesis
发明人：WUTS PETER; ELHAMMER AKE P
权利人:AUREOGEN BIOSCIENCES INC; AUEROGEN BIOSCIENCES INC
摘要:In general, the invention relates to AbA derivatives that are useful for treating infection. These novel compounds are shown to be effective in treating various fungal infections. The invention also provides pharmaceutically acceptable compositions comprising said compounds and methods of using the compositions in the treatment of various fungal infections.
专利号:WO-2018031521-A1
优先权日:2016-08-08
标 题:Aureobasidium derivatives and methods of synthesis
专利号:EP-3497113-A1
优先权日:2016-08-08
标题:Aureobasidium derivatives and methods of synthesis
专利号:AU-2017308814-A1
优先权日:2016-08-08
标题:Aureobasidium derivatives and methods of synthesis
专利号:US-2019292225-A1
优先权日:2016-08-08
标 题:Aureobasidium derivatives and methods of synthesis
专利号:CA-3033500-A1
优先权日:2016-08-08
标 题 :Aureobasidium derivatives and methods of synthesis
