CAS: 88669-04-9; Trospectomycin

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CAS号85951-30-0 (4aS,5aR,6S,7S,... | CAS号56733-83-6 N,N-bis(benzylo...

📜在 Pd-Baso4 吡啶,氢氟酸,氢气体系中,用 异丙醇,乙腈 作为反应溶剂,化学反应 7.3H,反应生成 丙大观霉素
参考文献:The Synthesis Of Trospectomycin (6'-N-Propylspectinomycin,U-63,366F) From Spectinomycin
标题:The Synthesis Of Trospectomycin (6'-N-Propylspectinomycin,U-63,366F) From Spectinomycin
摘要:
DOI:10.1016/s0040-4039(00)99493-0

专利信息

专利号:US-5856259-A
优先权日:1994-12-21
标 题:Preparation process of supported catalyst for the synthesis of methacrolein and methacrylic acid
发明人：WATANABE SEIGO; YOSHIOKA HITOSHI; IZUMI JINKO
权利人:MITSUBISHI RAYON CO
摘要:A process for producing a supported catalyst for the synthesis of methacrolein and methacrylic acid in which a catalytic active substance comprising a composite oxide containing molybdenum and bismuth as essential components is supported on the inside surface and/or the outside surface of an inert carrier, which comprises the steps of drying a mixed solution or an aqueous slurry containing the compounds of the elements constituting the catalytic active substance, subjecting the dried product to a primary calcination at a temperature in a range of 200°-400° C. to form a catalytic active substance precursor, comminuting the obtained catalytic active substance precursor to such an extent that the medium particle size in the volume-based particle size distribution becomes 10 μm or less, supporting the comminution product on an inert carrier, and subjecting it to a secondary calcination at a temperature which is 100° C. or more higher than the primary calcination temperature.

专利号:US-4578485-A
优先权日:1984-02-08
标 题 :Synthesis of spectinomycin analogs by an improved Grignard process
发明人：WHITE DAVID R
权利人:UPJOHN CO
摘要:The invention concerns a method for the synthesis of 6'-ethyl spectinomycin and analogs thereof, including intermediates utilized in the method. The method comprises converting an enamine by a Grignard addition to various novel dienones not hitherto known. The dienones are then hydrogenated and deblocked to obtain 6'-ethyl spectinomycin and analogs thereof. The 6'-ethyl spectinomycin and analogs thereof prepared by the invention exhibit especially good antibacterial activity.

专利号:US-5550095-A
优先权日:1992-05-08
标 题 :Process for producing catalyst used for synthesis of methacrylic acid
发明人：NAITO HIROYUKI; OTANI MASATO; OH-KITA MOTOMU; KURODA TORU
权利人:MITSUBISHI RAYON CO
摘要:PCT No. PCT/JP93/00597 Sec. 371 Date Nov. 4, 1994 Sec. 102(e) Date Nov. 4, 1994 PCT Filed May 7, 1993 PCT Pub. No. WO93/23161 PCT Pub. Date Nov. 25, 1993There is provided a process for efficient production of a solid catalyst usable for synthesis of methacrylic acid from methacrolein which comprises adding a lower alcohol or acetone to a dried product obtained from a mixed solution or aqueous slurry containing at least Mo, P and V as catalyst components and shaping the mixture by extrusion molding.

专利号:WO-9104256-A1
优先权日:1989-09-13
标 题 :Gamma alkylation of a protected derivative of the enone of spectinomycin
发明人：HERRINGTON PAUL M
权利人:UPJOHN CO
摘要:Process for alkylatine protected spectinomycin enone derivatives in the gamma position in order to produce intermediates useful in the synthesis of 6'alkylspectinomycins. The intermediate have formula (III) which comprises reacting a compound having formula (V) with a strong base and an alkenyl halide, wherein R1 is selected from the group consisting of alkoxycarbonyl, halogenated alkoxycarbonyl, aralkoxycarbonyl, and arylsulfone; R2 is selected from the group consisting of hydrogen, trimethylsilyl (TMS), tetrahydropyran (THP), and triethylsilyl (TES); A is selected from the group consisting of oxygen and sulfur; M is selected from the group consisting of lithium and potassium; and n is an integer from 1 to 3.

专利号:US-5220034-A
优先权日:1989-09-13
标 题:Protected derivatives of the enone of spectinomycin
发明人：HERRINTON PAUL M
权利人:UPJOHN CO
摘要:Process for alkylating protected spectinomycin enone derivatives in the gamma position in order to produce intermediates useful in the synthesis of 6'alkylspectinomycins. The intermediate have the formula ##STR1## which comprises reacting a compound having the formula ##STR2## with a strong base and an alkenyl halide, wherein R 1 is selected from the group consisting of alkoxycarbonyl, halogenated alkoxycarbonyl, aralkoxycarbonyl, and arylsulfone; R 2 is selected from the group consisting of hydrogen, trimethylsilyl (TMS), tetrahydropyran (THP), and triethylsilyl (TES); A is selected from the group consisting of oxygen and sulfur; M is selected from the group consisting of lithium and potassium; and n is an integer from 1 to 3.

专利号:JP-2003524567-A
优先权日:1997-08-15
标题:Electrical synthesis of hydroxylammonium salt and hydroxylamine using mediator, catalyst film, method for preparing catalyst film, and electrical synthesis of compound using catalyst film