CAS: 85474-75-5; 4-(Piperazin-1-yl)Benzoic Acid
该化合物是一种该化合物是一种苯并二酸核心,在4点方位上被一种管子铁合金所取代,这种结构具有芳香和基本特性,使其成为制药和农用化学合成中有价值的中间体,其管子子子素组增强了溶性和反应能力,有助于将其用于混合反应和生物活性分子的构件.该化合物在标准条件下的稳定性和与各种反应条件的兼容性进一步突出了其在医药化学和药物开发中的效用.其定义明确的化学特性确保了研究和工业应用中的再生性.
- 英文名称4-(Piperazin-1-yl)Benzoic Acid
- 中文名称4-(哌嗪-1-基)苯甲酸
- IUPAC名称4-(piperazin-1-yl)benzoic acid
- 其它别名4-(1-哌嗪基)苯甲酸; 4-Piperazin-1-Yl-Benzoic Acid Dihydrobromide
- CAS编号85474-75-5
- MFCD编号:MFCD03444417
- EINECS号:630-108-9
- 分子式:C11H14N2O2分子量:206.24
- 产品CID: 1851220
- 产品分类有机原料→分子砌块→芳环类化合物→苯类化合物
物理性质
MSDS等安全信息
欧盟法规
ECHA物质C&L通报上下游产品
4-fluorobenzoic acid ethyl ester 4-(4-(1,1-dimethylethoxycarbonyl)piperazin-1-yl)benzoic acid 4-(4-ethoxycarbonylphenyl)piperazine-1-carboxylic acid tert-butyl ester 4-(4-cyclopropanecarbonyl-piperazin-1-yl)-benzoic acid {(S)-1-[(S)-2-(4-{4'-[4-(4-cyclopropanecarbonyl-piperazin-1-yl)-benzoylamino]-biphenyl-4-yl}-1H-imidazol-2-yl)-pyrrolidine-1-carbonyl]-2-methyl-propyl}-carbamic acid methyl ester N-(4-bromo-phenyl)-4-(4-cyclopropanecarbonyl-piperazin-1-yl)-benzamide (S)-2-(4-{4'-[4-(4-Cyclopropanecarbonyl-piperazin-1-yl)-benzoylamino]-biphenyl-4-yl}-1H-imidazol-2-yl)-pyrrolidine-1-carboxylic acid tert-butyl ester合成工艺路线路线简述
- 合成目标产物 4-Piperazin-1-Yl-Benzoic Acid 主要起始原料 4-[4-(Tert-Butoxycarbonyl)Piperazino]Benzoic Acid
- (文献来源)合成步骤主要原料 4-[4-(Tert-Butoxycarbonyl)Piperazino]Benzoic Acid
📜对氟苯甲酸乙酯置于sodium Hydroxide,Potassium Carbonate体系中,用 盐酸,甲醇,乙醇,二甲基亚砜 作为反应溶剂,化学反应生成 4-(哌嗪-1-基)苯甲酸
参考文献:Novel Inhibitors Of Hepatitis C Virus
标题:Novel Inhibitors Of Hepatitis C Virus
摘要:该发明提供了以下式(I)的化合物: 其中变量在规范中定义,或其药用可接受盐,这些化合物是乙型肝炎病毒复制的抑制剂.该发明还提供了包括这些化合物的药物组合物,使用这些化合物治疗乙型肝炎病毒感染的方法,以及用于制备这些化合物的工艺和中间体.
海关参考信息
- 2905110000-甲醇
2906210000-苄醇
2912110000-甲醛
2912210000-苯甲醛 - 💡 提示：海关信息按照顺序优先匹配，如需确认的海关信息，请参考相关资料。
- 详情请参考：📖 海关编码查询和海关进出口税则
专利信息
专利号:US-9574189-B2
优先权日:2005-12-01
标题:Enzymatic encoding methods for efficient synthesis of large libraries
发明人：FRANCH THOMAS; LUNDORF MIKKEL DYBRO; JACOBSEN SØREN NYBOE; OLSEN EVA KAMPMANN; ANDERSEN ANNE LEE; HOLTMANN ANETTE; HANSEN ANDERS HOLM; SØRENSEN ANDERS MALLING; GOLDBECH ANNE; DE LEON DAEN; KALDOR DITTE KIEVSMOSE; SLØK FRANK ABILDGAARD; HUSEMOEN GITTE NYSTRUP; DOLBERG JOHANNES; Jensen Kim Birkebæ; PEDERSEN LENE; NØRREGAARD-MADSEN MADS; GODSKESEN MICHAEL ANDERS; GLAD SANNE SCHRØDER; NEVE SØREN; THISTED THOMAS; KRONBORG TINE TITILOLA AKINLEMINU; SAMS CHRISTIAN KLARNER; FELDING JAKOB; FRESKGÃ…RD PER-OLA; GOULIAEV ALEX HAAHR; PEDERSEN HENRIK
权利人:FRANCH THOMAS; LUNDORF MIKKEL DYBRO; JACOBSEN SØREN NYBOE; OLSEN EVA KAMPMANN; ANDERSEN ANNE LEE; HOLTMANN ANETTE; HANSEN ANDERS HOLM; SØRENSEN ANDERS MALLING; GOLDBECH ANNE; DE LEON DAEN; KALDOR DITTE KIEVSMOSE; SLØK FRANK ABILDGAARD; HUSEMOEN GITTE NYSTRUP; DOLBERG JOHANNES; Jensen Kim Birkebæ; PEDERSEN LENE; NØRREGAARD-MADSEN MADS; GODSKESEN MICHAEL ANDERS; GLAD SANNE SCHRØDER; NEVE SØREN; THISTED THOMAS; KRONBORG TINE TITILOLA AKINLEMINU; SAMS CHRISTIAN KLARNER; FELDING JAKOB; FRESKGÃ…RD PER-OLA; GOULIAEV ALEX HAAHR; PEDERSEN HENRIK; NUEVOLUTION AS
摘要:Disclosed is a method for obtaining a bifunctional complex comprising a molecule linked to a single stranded identifier oligonucleotide, wherein a nascent bifunctional complex comprising a chemical reaction site and a priming site for enzymatic addition of a tag is a) reacted at the chemical reaction site with one or more reactants, and b) reacted enzymatically at the priming site with one or more tag(s) identifying the reactant(s).
专利号:US-2009264300-A1
优先权日:2005-12-01
标题 :Enzymatic encoding methods for efficient synthesis of large libraries
