CAS: 74472-35-8; 2,3,3',4,6-Pentachlorobiphenyl
该化合物是多氯联苯(PCB)家族的成员,该家族由不同程度的氯化合成有机化学品组成.多氯联苯109的特点是其化学结构,包括一个双联骨柱,多个氯原子在特定位置被替换.该化合物一般没有颜色,光黄色固体或粘度液体,视其纯度和温度而定.多氯联苯109包括多氯联苯109,因其化学稳定性,疏水性和耐降解性而闻名,从而助长了其在环境中的持久性.它们也是亲脂性化学品,允许其在活生物体中进行生物累积.PC109已经研究其潜在的毒性影响,包括内分泌干扰和致癌性,导致对其使用和处置的管制限制.由于其环境持久性和潜在的健康风险,PC109被归类为一种危险物质,其处理受到严格的条例的约束,以降低接触和环境污染.
- 英文名称2,3,3',4,6-Pentachlorobiphenyl
- 中文名称2,3,3',4,6-五氯联苯
- IUPAC名称1,2,3,5-tetrachloro-4-(3-chlorophenyl)benzene
- 其它别名2,3,3',4,6-Pentachlorobiphenyl; 2,3,4,6,3'-Pentachlorobiphenyl
- CAS编号74472-35-8
- MFCD编号:MFCD00674461
- FDA UNII编号:5Q3UL7D7EI
- 分子式:C12H5Cl5分子量:326.43
- 产品CID: 1734768
- 产品分类分析化学 → 食品安全 → 二噁英，多氯联苯，呋喃
- 相似结构搜索
- 产品信息参考
;;;; - InChIKey: XGQBSVVYMVILEL-UHFFFAOYSA-N
- 1S/C12H5Cl5/c13-7-3-1-2-6(4-7)10-8(14)5-9(15)11(16)12(10)17/h1-5H
- 计算化学: 氢键受体数*氢键供体数*可旋转键数1.0
MSDS等安全信息
- 危险描述Not Classified
Reported as not meeting GHS hazard criteria by 3 of 3 companies. For more detailed information, please visit ECHA C&L website. - 安全声明The mechanism of action varies with the specific PCB. Dioxin-like PCBs bind to the aryl hydrocarbon receptor, which disrupts cell function by altering the transcription of genes, mainly be inducing the expression of hepatic Phase I and Phase II enzymes, especially of the cytochrome P450 family. Most of the toxic effects of PCBs are believed to be results of Ah receptor binding. Other PBCs are believed to interfere with calcium channels and/or change brain dopamine levels. PCBs can also cause endocrine disurption by altering the production of thyroid hormones and binding to estrogen receptors, which can stimulate the growth of certain cancer cells and produce other estrogenic effects, such as reproductive dysfunction. They will bioaccumulate by binding to receptor proteins such as uteroglobin. (A3, A4, A30, A66)
上下游产品
3-iod°Chlorobenzene 2,3,4,6-tetrachloroiodobenzene合成工艺路线路线简述
📜1-氯-3-碘苯,1,2,3,5-四氯-4-碘苯置于铜体系中,用 N,N-二甲基甲酰胺 作为反应溶剂,化学反应生成 2,3,3',4,6-五氯联苯
参考文献:Physical,Spectral And Chromatographic Properties Of All 209 Individual Pcb Congeners
标题:Physical,Spectral And Chromatographic Properties Of All 209 Individual Pcb Congeners
摘要:Physical,Spectral And Chromatographic Data For All 209 Individual Pcb Congeners Is Presented. The Individual Congeners Were Synthesized And Then Isolated And Purified. Recent Emphasis On The Source Of The Toxicity Of Commercial Pcb Formulations Has Increased The Need For A Complete Set Of The Pcb Congeners. Through The Use Of Two Capillary Gc Columns: 40% octadecyl/ 15% Phenyl Methyl Siloxane And 50% Phenyl Methyl Siloxane,It Was Possible To Separate 201 Pcb Congeners With Only Four Unresolved Pairs. The Data Compiled In This Study For All 209 Congeners Will Aid In The Identification Of Selected Individual Components Of These Environmental Pollutants. The Use Of This Data Also Presents The Opportunity For The Improved Quantification Of The Commercial Pcb Formulations.
DOI:10.1016/0045-6535(95)00140-4
海关参考信息
- 2903911000-邻二氯苯
- 💡 提示：海关信息按照顺序优先匹配，如需确认的海关信息，请参考相关资料。
- 详情请参考：📖 海关编码查询和海关进出口税则
供应商参考报价(招募中)
品牌试剂参考报价(招募中)
📌 第三方产品分析报告
合成参考文献
摘要:T14: Lewis RJ (1996). Sax's Dangerous Properties of Industrial Materials. 9th ed. Volumes 1-3. New York, NY: Van Nostrand Reinhold.
摘要:L4: ATSDR - Agency for Toxic Substances and Disease Registry (2000). Toxicological profile for polychlorinated biphenyls. U.S. Public Health Service in collaboration with U.S. Environmental Protection Agency (EPA).
摘要:L134: ATSDR - Agency for Toxic Substances and Disease Registry (2001). Minimal Risk Levels (MRLs) for Hazardous Substances. U.S. Public Health Service in collaboration with U.S. Environmental Protection Agency (EPA).
摘要:L135: International Agency for Research on Cancer (2014). IARC Monographs on the Evaluation of Carcinogenic Risks to Humans.
摘要:T6: World Health Organization (1993). Environ Health Criteria 140: Polychlorniated Biphenyls and Terphenyls.
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