CAS: 67-78-7; 2-((8S,9R,10S,11S,13S,14S,16R,17S)-16-Acetoxy-9-Fluoro-11,17-Dihydroxy-10,13-Dimethyl-3-Oxo-6,7,8,9,10,11,12,13,14,15,16,17-Dodecahydro-3H-Cyclopenta[a]Phenanthren-17-yl)-2-Oxoethyl Acetate (Triamcinolone Impurity)

相似化合物

3859-65-2 1177-87-3 3793-10-0

上下游产品

CAS号426-39-1 16α,21-Diacetox... | CAS号1171-81-9 11β,16α,17,21-t... | CAS号13951-70-7 16α-羟基泼尼松龙 | CAS号23460-76-6 21-Hydroxypregn... | CAS号74220-43-2 16alpha,17,21-t... | CAS号7333-34-8 16α,21-diacetox... | CAS号76-25-5 曲安奈德 | CAS号124-94-7 曲安西龙

16Alpha-羟基泼尼松龙置于1,4-二氧六环,吡啶,氯化亚砜,高氯酸,乙醇,氯仿,氢氟酸,Potassium Acetate体系中,化学反应生成 双乙酸呋曲安奈德
参考文献:16-Hydroxylated Steroids. Vii.1 The Synthesis Of The 16α-Hydroxy Derivatives Of 2-Methyl Steroids2
标题:16-Hydroxylated Steroids. Vii.1 The Synthesis Of The 16α-Hydroxy Derivatives Of 2-Methyl Steroids2
摘要:
DOI:10.1021/ja01516A044

专利信息

专利号:US-9051302-B2
优先权日:2008-01-15
标 题 :Synthesis of resorcylic acid lactones useful as therapeutic agents
发明人：WINSSINGER NICOLAS; BARLUENGA SOFIA; KARPLUS MARTIN
权利人:WINSSINGER NICOLAS; BARLUENGA SOFIA; KARPLUS MARTIN; UNIV STRASBOURG
摘要:Disclosed are macrocyclic compounds of formulae I, I′, II, II′, III, III′, IV, and V, which are analogs of the pochonin resorcylic acid lactones, pharmaceutical compositions comprising the compounds, and methods and uses comprising the compounds for the treatment of diseases mediated by kinases and Heat Shock Protein 90 HSP90.

专利号:US-8926955-B2
优先权日:2008-12-22
标题 :Synthesis of polymer conjugates of indolocarbazole compounds
发明人：BAGNOD RAFFAELLA; BECCARIA LUCA; BERTARIONE RAVA ROSSA LUISA; CRISCUOLO DOMENICO; LORENZETTO CHIARA; MAINERO VALENTINA; MARCONI ALESSANDRA; PINCELLI CARLO; TRAVERSA SILVIO
权利人:BAGNOD RAFFAELLA; BECCARIA LUCA; BERTARIONE RAVA ROSSA LUISA; CRISCUOLO DOMENICO; LORENZETTO CHIARA; MAINERO VALENTINA; MARCONI ALESSANDRA; PINCELLI CARLO; TRAVERSA SILVIO; CREABILIS S A
摘要:The present invention relates to a process for the preparation of polymer conjugates of indolocarbaxole compounds, in particular of polymer conjugates of K-252a and derivatives thereof, by a synthetic route which results in a highly pure product, with a high product yield. In a further aspect the present invention relates to novel polymer conjugates of K-252a and derivatives thereof, wherein the chemical group linking the polymer unity to the K-252a or to the K-252a derivative compound is characterized by a 5-member oxazolidindionic cyclic structure. These novel polymer conjugates are obtained through the novel synthetic route with high purity and high yields.

专利号:WO-9925385-A1
优先权日:1997-11-17
标 题:A method of increasing nucleic acid synthesis with ultrasound
发明人：UNGER EVAN C; MCCREERY THOMAS; SADEWASSER DAVID
权利人:IMARX PHARMACEUTICAL CORP
摘要:The present invention is directed to a method of increasing nucleic acid synthesis in a cell comprising administering to the cell a therapeutically effective amount of ultrasound for a therapeutically effective time such that said administration of said ultrasound results in said increased nucleic acid synthesis. The nucleic acid sequence may comprise an endogenous sequence or an exogenous sequence.

专利号:US-2021244638-A1
优先权日:2018-06-05
标 题:Inhibitors of glycosphingolipid synthesis and methods of use
发明人：CHATTERJEE SUBROTO B
权利人:SUBROTO B CHATTERJEE
摘要:Compositions in the prevention and treatment of skin diseases or associated disorders, inflammation or inflammatory diseases or disorders, include at least one inhibitor of glycosphingolipid synthesis.

专利号:CA-2747838-C
优先权日:2008-12-22
标 题 :Synthesis of polymer conjugates of indolocarbazole compounds

专利号:WO-2024233563-A1
优先权日:2023-05-09
标 题:6,6-fused bicyclic amides and compositions for use as 15-prostaglandin dehydrogenase modulators
发明人：GREENMAN KEVIN LLOYD; WANG HUI-LING; WEIRES NICHOLAS ANTHONY; ALLEN JOHN G; AMEGADZIE ALBERT K; BOURBEAU MATTHEW P; LI KEXUE
权利人:AMGEN INC
摘要:The present disclosure provides novel 15-hydroxy-prostaglandin dehydrogenase inhibitors, pharmaceutical compositions comprising such compounds, and methods of using such compounds and compositions in treating 15-hydroxy-prostaglandin dehydrogenase-mediated disease. Also provided are methods of making such compounds and intermediates thereof. The compounds have a structure of Formula (I): or a pharmaceutically acceptable salt thereof; wherein is Formula (i) or Formula (ii) Further, the disclosure provides intermediates useful in the synthesis of compounds of Formula (I).