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2-chloro-4-nitro-1-(phenylmethoxy)benzene tert-butyl ester(4-benzyloxy-3-chloro-phenyl)-carbamic acid tert-butyl ester N-(3-chloro-4-hydroxyphenyl)carbamic acid tert-butyl ester 2-mon°Chlorophenol 1-Methyl-cyclopropanecarboxylic acid (4-benzyloxy-3-chloro-phenyl)-amide 1-(benzyloxy)-2-chloro-4-isothi°Cyanatobenzene 海关参考信息
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2903919090-氯苯
2905110000-甲醇
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专利信息
专利号:CN-101203494-A
优先权日:2005-05-25
标 题 :Method for the synthesis of substituted 3-cyanoquinolines and intermediates thereof
专利号:US-2009111810-A1
优先权日:2007-10-23
标题:Substituted pyrimidine-5-carboxamide and 5-carboxylic ester kinase inhibitors
发明人:CONNOLLY PETER J; HUGHES TERRY V; WETTER STEVEN K
权利人:CONNOLLY PETER J; HUGHES TERRY V; WETTER STEVEN K
摘要:The present invention is directed to substituted pyrimidine-5-carboxamide and 5-carboxylic ester compounds of Formula (I): n n n n n n n n n n and forms thereof wherein R 1 , R 2 , R 3 , R 4 , R 5 , R 6 , R 7 and L are as defined herein and their synthesis and use as kinase inhibitors for treating a chronic or acute protein kinase mediated disease.
专利号:US-8367825-B2
优先权日:2005-12-21
标 题 :Substituted pyrimidinyl oxime kinase inhibitors
发明人:GUOZHANG XU; LEE LILY; HUGHES TERRY V; WETTER STEVEN K; CONNOLLY PETER J; ABAD MARTA C; EMANUEL STUART L; KAMACHI PRABHA S; MIDDLETON STEVEN A; BATTISTA KATHLEEN A; BIGNAN GILLES C
权利人:JANSSEN PHARMACEUTICA NV; GUOZHANG XU; LEE LILY; HUGHES TERRY V; WETTER STEVEN K; CONNOLLY PETER J; ABAD MARTA C; EMANUEL STUART L; KAMACHI PRABHA S; MIDDLETON STEVEN A; BATTISTA KATHLEEN A; BIGNAN GILLES C
摘要:The present invention is directed to substituted pyrimidine compounds of formula (I): n nand forms thereof, their synthesis and use for treating, preventing or ameliorating a chronic or acute protein kinase mediated disease, disorder or condition.