CAS: 59404-86-3; 4-(Benzyloxy)-3-Chloroaniline

该化合物是一种有机化合物,其特点是存在一个氯组,厌食动物和苯氧替代物,这种化合物一般在室温时是一种固体,在有机溶剂中可溶解,反映其芳香结构.该氯组引入了某种程度的电生殖性,它可在各种化学反应中影响其再活动,例如核嗜血替代物.苯氧基组增强了化合物的亲脂性,有可能影响其生物活动和与其他分子的相互作用.在安全方面,它与许多素一样,可能构成健康风险,包括毒性和潜在致癌性,需要在实验室环境中谨慎处理和采取适当的安全措施.其应用范围可能扩大到药物,农业化学品或有机合成的中间体,在那里,其独特的功能组群可以被用于进一步的化学转化.

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2-chloro-4-nitro-1-(phenylmethoxy)benzene tert-butyl ester(4-benzyloxy-3-chloro-phenyl)-carbamic acid tert-butyl ester N-(3-chloro-4-hydroxyphenyl)carbamic acid tert-butyl ester 2-mon°Chlorophenol 1-Methyl-cyclopropanecarboxylic acid (4-benzyloxy-3-chloro-phenyl)-amide 1-(benzyloxy)-2-chloro-4-isothi°Cyanatobenzene

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    专利信息


    专利号:CN-101203494-A
    优先权日:2005-05-25
    标 题 :Method for the synthesis of substituted 3-cyanoquinolines and intermediates thereof

    专利号:US-2009111810-A1
    优先权日:2007-10-23
    标题:Substituted pyrimidine-5-carboxamide and 5-carboxylic ester kinase inhibitors
    发明人:CONNOLLY PETER J; HUGHES TERRY V; WETTER STEVEN K
    权利人:CONNOLLY PETER J; HUGHES TERRY V; WETTER STEVEN K
    摘要:The present invention is directed to substituted pyrimidine-5-carboxamide and 5-carboxylic ester compounds of Formula (I): n n n n n n n n n n and forms thereof wherein R 1 , R 2 , R 3 , R 4 , R 5 , R 6 , R 7 and L are as defined herein and their synthesis and use as kinase inhibitors for treating a chronic or acute protein kinase mediated disease.

    专利号:US-8367825-B2
    优先权日:2005-12-21
    标 题 :Substituted pyrimidinyl oxime kinase inhibitors
    发明人:GUOZHANG XU; LEE LILY; HUGHES TERRY V; WETTER STEVEN K; CONNOLLY PETER J; ABAD MARTA C; EMANUEL STUART L; KAMACHI PRABHA S; MIDDLETON STEVEN A; BATTISTA KATHLEEN A; BIGNAN GILLES C
    权利人:JANSSEN PHARMACEUTICA NV; GUOZHANG XU; LEE LILY; HUGHES TERRY V; WETTER STEVEN K; CONNOLLY PETER J; ABAD MARTA C; EMANUEL STUART L; KAMACHI PRABHA S; MIDDLETON STEVEN A; BATTISTA KATHLEEN A; BIGNAN GILLES C
    摘要:The present invention is directed to substituted pyrimidine compounds of formula (I): n nand forms thereof, their synthesis and use for treating, preventing or ameliorating a chronic or acute protein kinase mediated disease, disorder or condition.

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    摘要:Joule, J. A., Science of Synthesis Knowledge Updates, (2018) 2, 98.
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