专利号:WO-2022228297-A1 优先权日:2021-04-26 标 题:Enzymatic preparation technique for acyl/aroyl coenzyme a 发明人:ZHU PING; ZHANG BOYONG; WANG HAO; GONG TING; CHEN TIANJIAO; CHEN JINGJING; YANG JINLING 权利人:INST OF MATERIA MEDICA CHINESE ACADEMY OF MEDICAL SCICENCES 摘要:Provided are a method for large-scale preparation of acyl/aroyl coenzyme A by an enzymatic method, i.e., using an acyltransferase to transfer acyl/aroyl from a cheap acyl/aroyl donor onto acyl/aroyl receptor coenzyme A, thereby achieving large-scale synthesis of acyl/aroyl coenzyme A, and a use of the method in the preparation of acyl/aroyl coenzyme A.
专利号:US-8017786-B2 优先权日:2006-05-15 标 题:Substituted β-phenyl-α-hydroxy-propanoic acid, synthesis method and use thereof 发明人:ZHENG XIAOHUI; ZHANG QUNZHENG; WANG SHIXIANG; ZHAO XINFENG 权利人:UNIV NORTHWEST 摘要:The present invention relates to a compound of the formula (I), wherein R 1 , R 2 and R 3 are each independently selected from H, OH, F, Cl, Br, methoxy and ethoxy; or alternatively, R 1 and R 2 together form —OCH 2 O—, R 3 is selected from H, OH, methoxy, ethoxy and halogens; R 4 is OH or acyloxy; R 5 is cycloalkoxyl, amino and substituted amino, and when R 5 is selected from amino, at least one of R 1 , R 2 and R 3 is not H. The present invention further relates to a process for synthesizing a compound of the formula (I), and use of the compound of the formula (I) in the manufacture of a medicament for the prevention or treatment of cardiovascular or cerebrovascular diseases.
专利号:CN-1337391-A 优先权日:2001-08-17 标题 :A New Process for the Phosgene Synthesis of a Class of Medicinal Acetylsalicylate Derivatives
专利号:AU-685274-B2 优先权日:1994-04-22 标题:Asymmetric synthesis of (R)- and (S)-arylethanolamines from iminoketones