CAS: 580-02-9; Methyl 2-Acetoxybenzoate

该化合物是属于酯类的有机化合物,其特点是芳香结构,其特点是一个甲氧基组和一个与苯环相连的丙氧基组,该化合物一般是一种无色的黄色液体,其香味甜味可粉黄,在乙醇和乙醚等有机溶剂中溶解,但由于其缺水芳香性质,其溶解性有限.甲基2-乙氧苯甲酸盐经常用于各种药品和香料的合成以及某些化妆品的配制,其化学特性包括核微粒体的再活动,使其在消化和凝聚反应中有用.此外,该化合物可能具有轻微毒性,需要适当的处理和安全防范.

结构式图片

欧盟法规

ECHA物质C&L通报REACH预注册

上下游产品

diazomethane aspirin acetic anhydride methyl salicylate 4-hydroxy[1]benzopyran-2-one methyl-3,5-dinitrosalicylate estere metilico dell'acido 5-acetilsalicilico methyl salicylate

合成工艺路线路线简述

    📜水杨酸甲酯 反应生成 乙酰水杨酸甲酯
    参考文献:Lapin,H.; Horeau,A.,Gazzetta Chimica Italiana,1963,Vol. 93,P. 451-454
    标题:Lapin,H.; Horeau,A.,Gazzetta Chimica Italiana,1963,Vol. 93,P. 451-454

    海关参考信息

    专利信息


    专利号:WO-2022228297-A1
    优先权日:2021-04-26
    标 题:Enzymatic preparation technique for acyl/aroyl coenzyme a
    发明人:ZHU PING; ZHANG BOYONG; WANG HAO; GONG TING; CHEN TIANJIAO; CHEN JINGJING; YANG JINLING
    权利人:INST OF MATERIA MEDICA CHINESE ACADEMY OF MEDICAL SCICENCES
    摘要:Provided are a method for large-scale preparation of acyl/aroyl coenzyme A by an enzymatic method, i.e., using an acyltransferase to transfer acyl/aroyl from a cheap acyl/aroyl donor onto acyl/aroyl receptor coenzyme A, thereby achieving large-scale synthesis of acyl/aroyl coenzyme A, and a use of the method in the preparation of acyl/aroyl coenzyme A.

    专利号:US-8017786-B2
    优先权日:2006-05-15
    标 题:Substituted β-phenyl-α-hydroxy-propanoic acid, synthesis method and use thereof
    发明人:ZHENG XIAOHUI; ZHANG QUNZHENG; WANG SHIXIANG; ZHAO XINFENG
    权利人:UNIV NORTHWEST
    摘要:The present invention relates to a compound of the formula (I), wherein R 1 , R 2 and R 3 are each independently selected from H, OH, F, Cl, Br, methoxy and ethoxy; or alternatively, R 1 and R 2 together form —OCH 2 O—, R 3 is selected from H, OH, methoxy, ethoxy and halogens; R 4 is OH or acyloxy; R 5 is cycloalkoxyl, amino and substituted amino, and when R 5 is selected from amino, at least one of R 1 , R 2 and R 3 is not H. The present invention further relates to a process for synthesizing a compound of the formula (I), and use of the compound of the formula (I) in the manufacture of a medicament for the prevention or treatment of cardiovascular or cerebrovascular diseases.

    专利号:CN-1337391-A
    优先权日:2001-08-17
    标题 :A New Process for the Phosgene Synthesis of a Class of Medicinal Acetylsalicylate Derivatives

    专利号:AU-685274-B2
    优先权日:1994-04-22
    标题:Asymmetric synthesis of (R)- and (S)-arylethanolamines from iminoketones

    供应商参考报价(招募中)

    品牌试剂参考报价(招募中)

    📌 第三方产品分析报告

    ✅ COA系统入驻 | 共享模式

    主要参考文献

    1. Chiplunkar PP, Zhao X, Tomke PD, Noro J, Xu B, Wang Q, Silva C, Pratap AP, Cavaco-Paulo A. Ultrasound-assisted lipase catalyzed hydrolysis of aspirin methyl ester. Ultrason Sonochem. 2018 Jan;40(Pt A):587-593. doi: 10.1016/j.ultsonch.2017.08.004. Epub 2017 Aug 5.

    合成参考文献


    摘要:Kleemann, A.; Engel, J.; Kutscher, B.; Reichert, D., Pharmaceutical Substances[Online], Thieme: Stuttgart, (2003).
    摘要:González-Bello, C.; Castedo, L., Science of Synthesis, (2007) 31, 305.
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