CAS: 55268-75-2; Cefuroxime

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CAS号1189-71-5 氯磺酰异氰酸酯 | CAS号56271-94-4 头孢呋辛钠EP杂质A | CAS号870-30-4 PHOSPHORIS°CYAN... | CAS号97232-97-8 头孢呋辛钠EP杂质E | CAS号56271-94-4 头孢呋辛钠EP杂质A | CAS号108-20-3 异丙醚 | CAS号64544-07-6 头孢呋辛酯

Cefuroxime Sodium置于盐酸体系中,用 水,丙酮 作为反应溶剂,以68.3%的收率获得产物头孢呋辛
参考文献:一种头孢呋辛赖氨酸及其制剂
标题:一种头孢呋辛赖氨酸及其制剂
摘要:本发明涉及一头孢呋辛赖氨酸化合物,其所述头孢呋辛赖氨酸中含有98~99.99Wt%的头孢呋辛赖氨酸,0.01~2%的反式头孢呋辛酸,反式头孢呋辛酸的分子式如式i所示:本发明得到的头孢呋辛赖氨酸的稳定性很强,高于现有技术,杂质含量和聚合物含量均低于现有技术的头孢呋辛赖氨酸,非常适用于临床应用.

专利信息

专利号:US-10925977-B2
优先权日:2006-10-05
标 题 :Efficient synthesis of chelators for nuclear imaging and radiotherapy: compositions and applications
发明人：YANG DAVID J; YU DONGFANG; THOMPSON ANDREW S
权利人:YANG DAVID J; YU DONGFANG; THOMPSON ANDREW S; CEIL POINT LLC; UNIV TEXAS
摘要:Novel methods of synthesis of chelator-targeting ligand conjugates, compositions comprising such conjugates, and therapeutic and diagnostic applications of such conjugates are disclosed. The compositions include chelator-targeting ligand conjugates optionally chelated to one or more metal ions. Methods of synthesizing these compositions in high purity are also presented. Also disclosed are methods of imaging, treating and diagnosing disease in a subject using these novel compositions, such as methods of imaging a tumor within a subject and methods of diagnosing myocardial ischemia.

专利号:US-2005186197-A1
优先权日:2002-08-29
标 题:Peptide inhibitors of beta lactamases
发明人：PALZKILL TIMOTHY; HUANG WANZHI
摘要:Peptide inhibitors of β-lactamases have been identified by the synthesis of peptide arrays using synthesis SPOT technology. These peptide inhibitors of β-lactamase have activity against a broad spectrum of β-lactamases and are useful in a variety of applications.

专利号:US-2006178357-A1
优先权日:2005-02-10
标题 :Chphalosporin-derived mercaptans as inhibitors of serine and metallo-beta-lactamases
发明人：BUYNAK JOHN D; CHEN HANSONG
权利人:BUYNAK JOHN D; CHEN HANSONG
摘要:Compounds of formula I: See Formula I in Figures Section n nwherein R 1 , R 2 , R 3 , R 4 and n have any of the values defined in the specification, and their pharmaceutically acceptable salts, are useful for inhibiting simultaneously serine and metallo-β-lactamase enzymes, for enhancing the activity of β-lactam antibiotics, and for treating β-lactam resistant bacterial infections in a mammal. The invention also provides pharmaceutical compositions, processes for preparing compounds of formula I, and novel intermediates useful for the synthesis of compounds of formula I.

专利号:US-8017776-B2
优先权日:2003-07-15
标题 :Methods for synthesis of acyloxyalkyl compounds
发明人：BHAT LAXMINARAYAN; GALLOP MARK A
权利人:XENOPORT INC
摘要:Disclosed herein are methods for synthesizing 1-(acyloxy)-alkyl prodrug derivatives of drugs through oxidation of 1-acyl-alkyl derivatives of drugs under anhydrous reaction conditions. The methods typically proceed stereospecifically, in high yield, do not require the use of activated intermediates and/or toxic compounds and are readily amenable to scale-up.

专利号:EP-0942745-B1
优先权日:1996-08-26
标题:Use of hyaluronidase
发明人：TUFVESON GUNNAR; HAELLGREN ROGER; JOHNSSON CECILIA; WAHLBERG JAN
权利人:TUFVESON GUNNAR; HAELLGREN ROGER; JOHNSSON CECILIA; WAHLBERG JAN
摘要:The use of hyaluronidase in the manufacturing of a drug for the treatment of conditions of interstitial edema in connection with organ grafting associated with an increased local content of hyaluronan in the connective tissue of a mammal. The drug comprises hyaluronidase in an amount giving a daily dosage of from 1 to 100,000 IU/kg body weight when given locally or systemically to a mammal. A method of treating conditions of interstitial edema in connection with organ grafting associated with an increased local synthesis of hyaluronan by systemic or local treatment with a pharmaceutical comprising hyaluronidase.

专利号:US-10443047-B2
优先权日:2014-05-01
标题 :Increasing cellular lipid production by increasing the activity of diacylglycerol acyltransferase and decreasing the activity of triacylglycerol lipase
发明人：TSAKRAKLIDES VASILIKI; BREVNOVA ELENA E
权利人:NOVOGY INC
摘要:Disclosed are methods and compositions for increasing the triacylglycerol content of a cell by up-regulating diacylglycerol acyltransferase and down-regulating triacylglycerol lipase. In some embodiments, a DGA1 protein is expressed and a native TGL3 gene is knocked out, thereby increasing the synthesis of triacylglycerol and decreasing its consumption, respectively.