CAS: 39884-48-5; 4-Aminobutan-2-Ol

相似化合物

167216-30-0 1311369-01-3 1255240-50-6

上下游产品

CAS号24621-61-2 (S)-(+)-1,3-丁二醇

📜(E)-4-(Diethoxyphosphorylamino)But-3-En-2-One置于sodium Tetrahydroborate体系中,用 乙醇 作为反应溶剂,化学反应 12.0H,反应生成 4-氨基-2-丁醇
参考文献:1-烯基膦酰胺酸二乙酯的新途径
标题:1-烯基膦酰胺酸二乙酯的新途径
摘要:研发了由可烯醇化的羰基化合物衍生的n-(二乙氧基磷酰基)亚胺的新途径.研究了三种不同的方法:(i)乙基-[N-(二乙氧基磷酰基)]-甲酰亚胺的氮杂-克莱森缩合与可烯醇化的酮;(II)n-亚磺酰基磷酸氨基二乙酯与脂肪族醛之间的反应;以及(iii)热裂解诱导的氨基磷酸二乙酯与酮二乙缩醛的反应.除两种情况外,所有产物均被鉴定为1-烯基膦酸二乙酯,在光谱上检测不到亚胺互变异构体.可以推荐将氮杂-克莱森缩合反应作为一种简单有效的方法,以合成1-乙基烯基-3-氧代膦酸二乙酯.
DOI:10.1016/s0040-4020(00)00568-8

专利信息

专利号:US-4705675-A
优先权日:1984-11-16
标题 :Synthesis of molecular sieving metallosilicates using silica-transition metal oxide sols
发明人：DESMOND MICHAEL J; PEPERA MARC A; CALLAHAN JAMES L
权利人:STANDARD OIL CO OHIO
摘要:A method for preparing a molecular sieving metallosilicate is disclosed which comprises (A) providing an aqueous dispersion of colloidal particles comprising contiguous mixtures of silica and the oxide of a transition metal selected from the group consisting of Sc, Ti, V, Cr, Mn, Fe, Co, Ni, Zn, Zr, Y or a mixture of two or more of said metals; (B) mixing an effective amount of a mineralizing agent and/or synthesis directing agent with said dispersion to form a gel; and (C) maintaining said gel at a temperature of about 80 DEG C. to about 300 DEG C. for an effective period of time to provide said metallosilicate.

专利号:US-4564511-A
优先权日:1984-11-16
标题 :Synthesis of molecular sieving metallosilicates using heteropolymetallates
发明人：DESMOND MICHAEL J; PESA FREDERICK A
权利人:STANDARD OIL CO OHIO
摘要:A method for preparing a molecular sieving metallosilicate is disclosed which comprises (A) providing a mixture comprising: water; an oxide of silicon source; a mineralizing agent and/or synthesis directing agent; and a heteropolymetallate of the formula AaLlMmJzOy .dH2O wherein A is an ion selected from the group consisting of hydrogen; one or more of the Group I-A to VI-A or Group I-B to VI-B metals; one or more of the rare earth metals; ammonium, alkyl ammonium, alkyl phosphonium or alkyl arsonium; or a mixture of two or more thereof; M is Zn, Ga, Ge, Ti, Cr, Mn, Fe, Co, B, Ni, Rh, Zr or a mixture of two or more thereof; L is P, As, Si, Al, H or a mixture of two or more thereof; J is Mo, W, V, Nb or a mixture of two or more thereof; a is a number which when multiplied by the charge of A will result in balancing the charge on the complex within the brackets; l is a number ranging from zero to about 20; m is a number ranging from zero to about 20; z is a number ranging from about 1 to about 50; y is a number ranging from about 7 to about 150; d is a number ranging from about zero to about 150; and (B) maintaining said mixture at a temperature of about 80 DEG C. to about 300 DEG C. for an effective period of to form said molecular sieving metallosilicate.

专利号:US-2004053999-A1
优先权日:1997-09-17
标题 :Novel compounds and methods for synthesis and therapy
发明人：BISCHOFBERGER NORBERT W; DAHL TERRENCE C; HITCHCOCK MICHAEL J M; KIM CHOUNG U; LEW WILLARD; LIU HONGTAO; MILLS ROGER G; WILLIAMS MATTHEW A
摘要:Novel compounds are described. The compounds generally comprise an acidic group, a basic group, a substituted amino or N-acyl and a group having an optionally hydroxylated alkane moiety. Pharmaceutical compositions comprising the inhibitors of the invention are also described. Methods of inhibiting neuraminidase in samples suspected of containing neuraminidase are also described. Antigenic materials, polymers, antibodies, conjugates of the compounds of the invention with labels, and assay methods for detecting neuraminidase activity are also described.

专利号:US-2005043560-A1
优先权日:2000-06-19
标题:Novel beta-hydroxyamides
发明人：MANEA MIRCEA; PETERSSON CECILIA
权利人:PERGO EUROP AB
摘要:Disclosed is a novel β-hydroxylamide of general formula n n nwherein R 1 is a linear or branched aliphatic hydrocarbon group optionally comprising one or more ether and/or ester units, such as a group derived from at least one hydroxyfunctional n ncompound, R 2 is a linear or branched aliphatic and/or aromatic hydrocarbon group, such as a group derived from at least one carboxyfunctional compound or at least one anhydride halide or ester of a carboxyfunctional compound, R 3 is N-alkyl or N-cycloalkyl for instance derived from at least one alkanolamine, and wherein m is an integer and at least 1 and n is an integer and at least 2, In a further aspect the present invention refers to a process for synthesis of said β-hydroxyamide. The process comprises the Steps of (i) subjecting a di, tri or polyalcohol to alcoholysis with at least one di, tri or polyalkyl ester of a di, tri or polyfunctional carboxylic acid and (ii) subjecting obtained reaction product to aminolysis with at least one alkanolamine.

专利号:US-2003195373-A1
优先权日:2000-06-19
标 题 :Novel beta-hydroxyamides
发明人：MANEA MIRCEA; PETERSSON CECILIA
摘要:Disclosed is a noble β-hydroxyamide of general formula wherein R 1 is alkyl, alkoxyalkyl or hydroxyalkoxyalkyl derived from at least one hydroxyfunctional compound, R 2 is alkyl, aryl, alkylaryl or arylalkyl derived from at least one carboxyfunctional compound or at least one anhydride, halide or ester of at least one carboxyfunctional compound, R 3 is N-alkyl or N-cycloalkyl derived from at least one alkanolamine and wherein m and n are independent integers and at least 1. In a further aspect the present refers to a process for synthesis of said β-hydroxyamide. The process comprises the Steps of (i) subjecting a di, tri or polyalcohol to alcoholysis with at least one di, tri or polyalkyl ester of a di, tri or polyfunctional carboxylic acid and (ii) subjecting obtained reaction product to aminolysis with at least one alkanolamine.

专利号:US-6225341-B1
优先权日:1995-02-27
标 题:Compounds and methods for synthesis and therapy
发明人：BISCHOFBERGER NORBERT W; KIM CHOUNG U; LEW WILLARD; LIU HONGTAO; WILLIAMS MATTHEW A
权利人:GILEAD SCIENCES INC
摘要:Novel compounds are described. The compounds generally comprise an acidic group, a basic group, a substituted amino or N-acyl and a group having an optionally hydroxylated alkane moiety. Pharmaceutical compositions comprising the inhibitors of the invention are also described. Methods of inhibiting neuraminidase in samples suspected of containing neuraminidase are also described. Antigenic materials, polymers, antibodies, conjugates of the compounds of the invention with labels, and assay methods for detecting neuraminidase activity are also described.