CAS: 3777-69-3; 2-Pentylfuran

相似化合物

4229-91-8 3777-70-6 3777-71-7

上下游产品

(E)-2-(pent-1-en-1-yl)furan 2-(phenoxymethyl)furan butyl magnesium bromide benzene nonan-4-one (2E)-4-oxo-2-nonenal 3-(5-Pentyl-furan-2-yl)-cyclohexanone (5-pentyl-2-furyl)diphenylmethane

1-辛烯-3-醇置于grubbs Catalyst First Generation,Sodium Hydride,对甲苯磺酰氯,间氯过氧苯甲酸,Lithium Diisopropyl Amide体系中,用 四氢呋喃,二氯甲烷 用作溶剂,化学反应 2.0H,反应生成2-正戊基呋喃
参考文献:使用二氢吡喃氧化物的闭环复分解和碱基诱导重排合成密集功能化的 2,3-二氢吡喃
标题:使用二氢吡喃氧化物的闭环复分解和碱基诱导重排合成密集功能化的 2,3-二氢吡喃
摘要:描述了二氢吡喃和二氢呋喃氧化物的制备以及它们在二烷基氨基锂存在下的重排分别为官能化的 2,3-二氢吡喃或 2,3-二氢呋喃.反应的区域化学结果会受到起始环氧化物的相对构型和碱的空间需求的影响.获得的 2,3-二氢吡喃通过碳-费里耶反应立体选择性地转化为双官能化的 3,4-二氢吡喃,或通过添加二甲酮(由硝酸铈铵介导)转化为稠合的缩醛.立体化学结果通过机械建议合理化.
Doi:10.1002/1099-0690(200009)2000:18<3145::Aid-Ejoc3145>3.0.Co;2-B

专利信息

专利号:US-4360688-A
优先权日:1981-05-21
标题 :Precursors and synthesis of d1-(methyl)-16,16-(dimethyl)-11-alpha, 15-alpha, beta-dihydroxy-9-oxo-2,13,-trans, trans-prostadienoates
发明人：FLOYD JR MIDDLETON B
权利人:AMERICAN CYANAMID CO
摘要:Novel compounds are disclosed of the classes: ##STR1## wherein the subscript n is an integer from 3-5, inclusive, R 1 is hydrogen or R 2 ; R 2 and R 3 consist essentially of C 1 -C 6 alkyl and R 2 may be the same as or different from R 3 , and wherein Aryl consists essentially of phenyl and phenyl substituted with halogen, C 1 -C 4 alkyl, C 1 -C 4 alkoxy, and trifluoromethyl; n (b) derivatives of furan having the formula ##STR2## wherein R 4 consists essentially of hydrogen and C 1 -C 6 alkyl, and W is either carbonyl or carbinol; and n (c) cyclopentenonyl compounds having the formulas ##STR3## wherein R 5 consists essentially of hydrogen and C 1 -C 6 alkyl, P 1 is hydrogen or a protective group, Y is either ##STR4## A new process is disclosed for preparing 1-(methyl)-16,16-(dimethyl)-11-alpha-15-alpha-dihydroxy-9-oxo-2,13,trans, trans-prostadienoate, and congeners thereof, including racemic mixtures.

专利号:US-5166369-A
优先权日:1981-05-21
标题:Precursors and synthesis of D1-(methyl)-16,16-(dimethyl)-11-alpha, 15-alpha, beta-dihydroxy-9-oxo-2,13,-trans, trans-prostadienoates
发明人：FLOYD JR MIDDLETON B
权利人:AMERICAN CYANAMID CO
摘要:Novel compounds are disclosed of the derivatives of furan having the formula ##STR1## wherein R 4 consists essentially of hydrogen and C 1 -C 6 alkyl, and W is either carbonyl or carbinol and N is from 3-5.

专利号:US-4983753-A
优先权日:1981-05-21
标题 :Precursors and synthesis of di-(methyl)-16,16-(dimethyl)-11-alpha,15-alpha beta-dihydroxy-9-oxo-2,13-trans,trans-prostadienoates
发明人：FLOYD JR MIDDLETON B
权利人:FLOYD JR MIDDLETON B
摘要:Novel compounds are disclosed of the classes: ##STR1## wherein the subscript n is an integer from 3-5, inclusive, R 1 is hydrogen or R 2 ; R 2 and R 3 consist essentially of C 1 -C 6 alkyl and R 2 may be the same as or different from R 3 , and wherein Aryl consists essentially of phenyl and phenyl substituted with halogen, C 1 -C 4 alkyl, C 1 -C 4 alkoxy, and trifluoromethyl; n (b) derivatives of furan having the formula ##STR2## wherein R 4 consists essentially of hydrogen and C 1 -C 6 alkyl, and W is either carbonyl or carbinol; and n (c) cyclopentenonyl compounds having the formulas ##STR3## wherein R 5 consists essentially of hydrogen and C 1 -C 6 alkyl, P 1 is hydrogen or a protective group, Y is either ##STR4## or ##STR5## A conjugate addition reaction is disclosed, whereby the reaction of ##STR6## with a lithio-cuprate reagent produces compounds of the class: ##STR7## A new process is disclosed for preparing 1-(methyl)-16,16-dimethyl-11-alpha-15-alpha-dihydroxy-9-oxo-2,13,trans,trans-prostadienoate, and congeners thereof, including racemic mixtures.

专利号:US-8350090-B1
优先权日:2011-08-24
标题 :Processes for preparing cyclopentenones and cyclopentenones for the synthesis of benzindene prostaglandins
发明人：WEI SHIH-YI; CHANG WAN-CHUN; YEH YU-CHIH
权利人:CHIROGATE INT INC; WEI SHIH-YI; CHANG WAN-CHUN; YEH YU-CHIH
摘要:The present invention provides novel processes of preparing racemic and optically active cyclopentenones of Formula I: n nThe invention also provides novel cyclopentenones of formula I in racemic or optically active form.

专利号:US-4474979-A
优先权日:1981-05-21
标 题:Synthesis of d1-(methyl)-16,16-(dimethyl-11-alpha, 15-alpha, beta-dihydroxy-9-oxo-2,13,-trans,trans-prostadienoates
发明人：FLOYD JR MIDDLETON B
权利人:AMERICAN CYANAMID CO
摘要:A conjugate addition reaction and novel intermediate compounds are disclosed, whereby the reaction of ##STR1## with a lithio-cuprate reagent ##STR2## produces compounds of the class: ##STR3## A new process is disclosed for preparing 1-(methyl)-16,16-(dimethyl)-11-alpha-15-alpha-dihydroxy-9-oxo-2,13,trans,trans-prostadienoate, and congeners thereof, including racemic mixtures.

专利号:WO-2018002957-A2
优先权日:2016-06-29
标题 :A method for synthesis of 6-deoxy-l-hexoses from l-rhamnose