CAS: 347418-42-2; 4-Chloro-5-Fluoropyrimidine

相似化合物

213265-83-9 2927-71-1 6693-08-9

上下游产品

5-fluoro-4-hydroxypyrimidineN-(5-(4-acetylpiperazin-1-yl)pyridin-2-yl)-2-(4-(5-fluoropyrimidin-4-yl)phenyl)acetamide 5-fluoropyrimidin-4-amine (5S)-1-((2R)-3-Cyclopentyl-2-{[formyl(hydroxy)amino]methyl}propanoyl)-N-(5-fluoro-4-pyrimidinyl)-4,5-dihydro-1H-pyrazole-5-carboxamide voriconazole

5-氟-4-羟基嘧啶置于三氯氧磷体系中,化学反应生成 4-氯-5-氟嘧啶
参考文献:Kheifets; Kol'Tsov; Khachaturov,Russian Journal Of Organic Chemistry,2000,Vol. 36,# 9,P. 1373-1387
标题:Kheifets; Kol'Tsov; Khachaturov,Russian Journal Of Organic Chemistry,2000,Vol. 36,# 9,P. 1373-1387

专利信息

专利号:US-12054512-B2
优先权日:2017-11-10
标 题 :Sting modulator compounds, and methods of making and using
发明人：VYSKOCIL STEPAN; CIAVARRI JEFFREY; CULLIS COURTNEY; ENGLAND DYLAN BRADLEY; GOULD ALEXANDRA E; GREENSPAN PAUL; HU YONGBO; LANGSTON STEVEN; LI GANG; MIZUTANI HIROTAKE; OKANIWA MASANORI
权利人:TAKEDA PHARMACEUTICALS CO
摘要:The present disclosure provides STING modulators/agonists, and methods of synthesis and methods for using for the prophylaxis or treatment of cancer and other STING-related diseases.The present disclosure relates to a compound represented by the Formula (I):wherein each symbol is as defined in the description, or a pharmaceutically acceptable salt thereof.