CAS: 3366-95-8; 1-(2-Methyl-5-Nitro-1H-Imidazol-1-yl)Propan-2-Ol

相似化合物

443-48-1 1010-93-1 618911-61-8

上下游产品

1-bromo-2-propanol 2-methyl-5-nitro-1H-imidazole methyloxirane 1-(2-methyl-imidazol-1-yl)-propan-2-ol 1-[4-(4-fluorobenzenesulfonylmethyl)-2-methyl-5-nitroimidazol-1-yl]propan-2-ol 1-(2-methyl-5-nitro-1H-imidazol-1-yl)propan-2-yl (E)-3-p-tolylacrylate 1-(2-methyl-5-nitro-1H-imidazol-1-yl)propan-2-yl (E)-3-(3-fluorophenyl)acrylate 1-(2-methyl-5-nitro-1H-imidazol-1-yl)propan-2-yl (E)-3-(2-chlorophenyl)acrylate

专利信息

专利号:US-9382288-B2
优先权日:2010-10-06
标题 :Derivatives of steroid benzylamines, having an antiparasitic antibacterial, antimycotic and/or antiviral action
发明人：BECKER KATJA; KRIEG REIMAR; SCHÖNECKER BRUNO
权利人:BECKER KATJA; KRIEG REIMAR; SCHÖNECKER BRUNO; UNIV GIESSEN JUSTUS LIEBIG
摘要:The present invention relates to compounds derived from steroids of the general formula (I) n nwherein L represents a linker and R # represents a steroid residue, the use of compounds of the general formula (I) in medicine and for the prophylaxis and/or the treatment of infectious diseases. Furthermore described are pharmaceutical compositions containing at least one compound of the general formula (I). A further aspect of the invention relates to the synthesis of said compounds of the general formula (I).

专利号:WO-2005105153-A1
优先权日:2004-04-30
标 题 :Hydroxyalkyl derivatives of biologically active compounds
发明人：DESHPANDE JAYANT VENKATESH; KADAM VAISHALI MADHUKAR; GUPTE VANDANA SANDEEP; RANBHAN KAMLESH JAYANTILAL
权利人:KOPRAN RES LAB LTD; DESHPANDE JAYANT VENKATESH; KADAM VAISHALI MADHUKAR; GUPTE VANDANA SANDEEP; RANBHAN KAMLESH JAYANTILAL
摘要:Hydroxyalkyl derivatives of biologically active compounds represented by the formula VII wherein R2 = H, CI-12 alkyl, C6-12 aryl, or -OH and D = Biologically active agent having functional groups such as Formula (a) epoxy or aziridine and Z' = Formula (b) L= spacer comprising (un)substituted alkyl, hydroxyalkyl or alkoxy alkyl with the condition that the carbon chain length contains 2 to 6 carbon atoms when Z' = Formula (c) and pharmaceutically acceptable acid addition salts and enantiomers thereof Also process for the synthesis of compounds of the Formula VII and pharmaceutically acceptable acid addition salts and enantiomers thereof comprising condensation of the biologically active agents having functional groups such as Formula (d) epoxy or azifidine with substituted alkyl derivatives under alkaline conditions, at 20 - 80°C, in an organic solvent.

专利号:WO-2025086625-A1
优先权日:2023-10-26
标题 :Synthesis method for deuterated tinidazole
发明人：MEI SHU; GUO HUI; CHEN WULIAN
权利人:ANPEL LABORATORY TECH SHANGHAI INC
摘要:The present invention relates to a synthesis method for a deuterated tinidazole. The deuterated tinidazole is as represented by formula I, wherein one or more of R 1 -R 5 are deuterium, and the rest is hydrogen. The synthesis method comprises the step of oxidizing an intermediate B with m-chloroperoxybenzoic acid to prepare the deuterated tinidazole, wherein the oxidation is carried out under low-temperature and alkaline conditions; and the intermediate B is as represented by formula II. By using the synthesis method of the present invention, the problems of deuterium shedding and isotope dilution in the reaction process can be avoided, and the stable isotope-labeled deuterated tinidazole with the isotope abundance of > 98% is obtained with a higher yield. The prepared deuterated tinidazole can be used as an isotope internal standard reagent for the quantitative detection of tinidazole, which, for example, can be used to detect residual tinidazole in meat products by means of an isotope internal standard method, and has the advantages of having high recovery efficiency from a matrix, and being environmentally friendly and safe.

专利号:CN-102675211-A
优先权日:2011-03-17
标 题 :Synthesis of Secnidazole Cinnamate Derivatives and Its Application in Antibacterial Drugs

专利号:CN-113461957-B
优先权日:2021-06-01
标 题 :A kind of three-dimensional rare earth terbium compound and its synthesis method and application

专利号:CN-113461616-A
优先权日:2021-07-16
标 题 :A kind of synthesis technology of 2-methyl-5 nitroimidazole