CAS: 2557-77-9; 3-Fluorobenzenethiol

该化合物是一种含分子式C6H5FS的氟芳烃硫醇,该化合物是有机合成的多用途中间体,特别是在制备药品,农用化学品和特殊材料方面.氟和硫醇功能组的存在增强了其反应性,能够有选择地衍生出交叉反应,核循环代用品和金属复合组装.在受控条件下,其高纯度和稳定性使其适合于精密的化学制造.氟代苯具有独特的电子和不动特性,影响衍生化合物的再活性和结合性.由于潜在的挥发性和气味,需要妥善处理.

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CAS号1121-86-4 3-氟碘苯 | CAS号364-78-3 4-氟-2-硝基苯胺 | CAS号402-67-5 间氟硝基苯 | CAS号625-98-9 间氯氟苯 | CAS号372-19-0 3-氟苯胺 | CAS号110211-86-4 3-fluorophenyl ... | CAS号331-55-5 (3-Fluoro-pheny... | CAS号1073-06-9 间溴氟苯 | CAS号63930-17-6 3,3'-二氟二苯二硫醚 | CAS号701-27-9 3-氟苯磺酰氯 | CAS号658-28-6 3-氟茴香硫醚 | CAS号331-55-5 (3-Fluoro-pheny... | CAS号61081-26-3 2-(3-fluorophen... | CAS号61081-29-6 2-(3-fluorophen...

合成工艺路线路线简述

    4-氟-2-硝基苯胺置于三氯化铁 盐酸,氢氧化钾,硫酸,一水合肼,锌,Sodium Nitrite体系中,用 乙醇 用作溶剂,化学反应 25.0H,反应生成3-氟苯硫酚
    参考文献:Protiva,Miroslav; Jilek,Jiri; Cervena,Irena,Collection Of Czechoslovak Chemical Communications,1986,Vol. 51,# 11,P. 2598-2616
    标题:Protiva,Miroslav; Jilek,Jiri; Cervena,Irena,Collection Of Czechoslovak Chemical Communications,1986,Vol. 51,# 11,P. 2598-2616

    专利信息


    专利号:US-10150160-B2
    优先权日:2014-12-04
    标题 :Universal one-pot and up-scalable synthesis of SERS encoded nanoparticles
    发明人:PAZOS PÉREZ NICOLÃ?S; MIR DE SIMÓN BERNAT
    权利人:MEDCOM ADVANCE S A; MEDCOM ADVANCE S A
    摘要:The universal one-pot and up-scalable synthesis of SERS encoded nanoparticles relies on the controlled co-absorption of mercaptoundecanoic acid (MUA) and the Raman code on the metallic surfaces of the nanoparticles. In contrast to most of the reported procedures which typically involve complex steps, the present method has demonstrated to be an easy and fast one-pot approach for the production of SERS-encoded nanoparticles. This versatile strategy allows for the SERS codification of particles with every molecule with affinity toward the metal surface, independently of its chemical nature, as exemplified here in the fabrication of 31 different encoded particles using the same standard procedure. In addition to the easiness of preparation, scalability to the liter regime, stability in aqueous solutions including PBS and chemical diversity, our SERS-encoded particles show considerably higher optical efficiency than those fabricated by using PEG or PVP polymers.

    专利号:US-9365494-B2
    优先权日:2008-12-18
    标 题 :Process for synthesis of amino-methyl tetralin derivatives
    发明人:DURKIN KIERAN; FISHER LAWRENCE EMERSON; MEILI ARTHUR; SCALONE MICHAELANGELO; SHI XIANQING; VITALE JUSTIN
    权利人:DURKIN KIERAN; FISHER LAWRENCE EMERSON; MEILI ARTHUR; SCALONE MICHAELANGELO; SHI XIANQING; VITALE JUSTIN; ROCHE PALO ALTO LLC
    摘要:Methods for producing a compound of formula k1 or k2 n nby reducing a dihydronapthalene amide compound of formula in n nwith hydrogen gas in the presence of a ruthenium catalyst of formula j1 or j2n nRu(Z) 2 (L)  j1;n nRu(E)(E′)(L)(D)  j2;n nwherein m, n, Ar, Y, R 1 E, E′, D, Z and L are as defined herein.

    专利号:US-2016318862-A1
    优先权日:2013-09-25
    标 题:Synthesis of delta 12-pgj3 and related compounds
    发明人:NICOLAOU KYRIACOS C; HERETSCH PHILIPP; HALE CHRISTOPHER R H; EL GHZAOUI ABDELLATIF EL MARROUNI; PULUKURI KIRAN KUMAR; YU RUOCHENG; GROVE CHARLES
    权利人:UNIV RICE WILLIAM M
    摘要:In one aspect, the present invention provides novel derivatives of Δ 12 -PGJ 3 and modular synthetic pathways to obtaining Δ 12 -PGJ 3 and derivatives thereof. In some aspects, the present derivatives of Δ 12 -PGJ 3 are useful as chemotherapeutic agents. The present disclosure also describes compositions of these derivatives as well as methods of use of the derivatives thereof.

    专利号:US-9481685-B2
    优先权日:2008-10-02
    标 题:Imaging neuroinflammation
    发明人:WADSWORTH HARRY JOHN; SHAN BO; O'SHEA DENNIS; PASSMORE JOANNA MARIE; TRIGG WILLIAM JOHN
    权利人:WADSWORTH HARRY JOHN; SHAN BO; O'SHEA DENNIS; PASSMORE JOANNA MARIE; TRIGG WILLIAM JOHN; GE HEALTHCARE LTD
    摘要:The present invention concerns in vivo imaging and in particular in vivo imaging of the peripheral benzodiazepine receptor (PBR). A tetracyclic indole in vivo imaging agent is provided that binds with high affinity to PBR, has good uptake into the brain following administration, and which preferentially binds to tissues expressing higher levels of PBR. The present invention also provides a precursor compound useful in the synthesis of the in vivo imaging agent of the invention, as well as a method for synthesis of said in vivo imaging agent comprising use of said precursor compound, and a kit for carrying out said method. A cassette for the automated synthesis of the in vivo imaging agent is also provided. In addition, the invention provides a radiopharmaceutical composition comprising the in vivo imaging agent of the invention, as well as methods for the use of said in vivo imaging agent.

    专利号:US-9751851-B2
    优先权日:2013-09-20
    标 题:Molecules and compositions that inhibit gram negative bacteria and their uses
    发明人:BASSLER BONNIE L; SEMMELHACK MARTIN F; DRESCHER KNUT; SIRYAPORN ALBERT; CONRAD-MILLER LAURA C; O'LOUGHLIN COLLEEN T
    权利人:UNIV PRINCETON; BASSLER BONNIE L; SEMMELHACK MARTIN F; DRESCHER KNUT; SIRYAPORN ALBERT; MILLER LAURA C; O'LOUGHLIN COLLEEN T
    摘要:Antivirulence strategies to combat Pseudomonas aeruginosa , are described. One strategy encompasses synthesis of a series of compounds that inhibit the production of pyocyanin, a redox-active virulence factor produced by this pathogen. A related strategy encompasses synthesis of compounds that inhibit the two P. aeruginosa quorum-sensing receptors, LasR and RhlR, inhibit production of pyocyanin, and inhibit biofilm formation.

    专利号:EP-2104157-A1
    优先权日:2006-12-29
    标题 :Solution containing organic el material, method for synthesis of organic el material, compound synthesized by the synthesis method, method for formation of thin film of organic el material, thin film of organic el material, organic el element
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    合成参考文献


    摘要:Xu, H.; Dai, H.-X., Science of Synthesis: Special Topics, (2022) 1, 195.
    摘要:Kwiatkowska, M.; Kiełbasiński, P., Science of Synthesis: Knowledge Updates, (2024) 3, 424.
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