CAS: 2116-65-6; 4-Benzylpyridine

该化合物是一种有机化合物,其特征为4点方位以苯基组替代的环状环状环状虫状物.分子分子式为C12H11N,表示含有12个碳原子,11个氢原子和1个氮原子.该化合物一般是无色的黄色液体,可粉色,具有独特的芳香味.它溶于乙醇和乙醚等有机溶剂,但由于苯基组的疏水性,其溶解性有限. 4-苯丙烯基因环内的氮原子而表现出基本特性,允许其参与各种化学反应,包括核分裂性代用品和电药用芳香替代物.它用于有机合成,并可作为更复杂的分子的建筑块.此外,它在制药行业和在协调化学中具有应用性.在处理这一化合物时,应采取安全防范措施,因为如果吸入或吸入,可能会对健康造成风险.

结构式图片

欧盟法规

ECHA物质C&L通报REACH预注册

上下游产品

pyridine pyridine hydr°Chloride benzyl chloride iodomethylbenzene 4-benzyl-1-(3-trimethylammonio-propyl)-pyridinium; dibromide 4-[2-(4-chloro-phenyl)-1-phenyl-vinyl]-pyridine (E)-4-(1,2-diphenylvinyl)pyridine 2,4-dibenzylpyridine

合成工艺路线路线简述

    📜N-Ethoxycarbonylpyridinium Chloride置于氧气体系中,化学反应生成4-苄基吡啶
    参考文献:通过使用混合的铜,锌苄基有机金属化合物轻松合成官能化的4-苄基吡啶
    标题:通过使用混合的铜,锌苄基有机金属化合物轻松合成官能化的4-苄基吡啶
    摘要:描述了一种通用方法,该方法是使用高度官能化的混合铜锌,苄基有机金属与n-乙氧基羰基吡啶鎓氯化物反应,经氧氧化后生成区域选择性的4-苄基吡啶,产率为30-75%.
    Doi:10.1016/s0040-4039(00)78900-3

    海关参考信息

    专利信息


    专利号:WO-8602628-A1
    优先权日:1984-11-04
    标题:Process for removal of hydrogen sulfide from gases
    发明人:LYNN SCOTT
    权利人:UNIV CALIFORNIA
    摘要:Two stage removal of hydrogen sulfide from a gas. In the first stage solutions of hydrogen sulfide and sulfur dioxide in a solvent react to produce sulfur and water. An excess of hydrogen sulfide is maintained in the first stage resulting in a solution containing sulfur, water and the excess hydrogen sulfide, or resulting in a gas containing the excess hydrogen sulfide. The excess hydrogen sulfide in the solution or in the gas is then treated in a second stage with a solution in the same solvent of sulfur dioxide in excess of or closely equal to that required to react with the hydrogen sulfide. Excess sulfur dioxide in the vapor phase from the second stage may be absorbed in neat solvent. The solvent is selected to have a high solvating power for sulfur dioxide, a lesser but substantial solvating power for hydrogen sulfide and to promote the reaction of hydrogen sulfide with sulfur dioxide. Such gases as natural gas, synthesis gas, and the tail gas of a claus plant may be so treated. By appropriate selection of solvents and/or conditions, accompanying minor components of the gas stream being treated may be removed and recovered if of value, e.g., propane from natural gas, carbon dioxide and water from synthesis gas, etc. The process avoids the need to maintain exact stoichiometric ratios of hydrogen sulfide and sulfur dioxide, it avoids the need to use high flow rates of solvent, a liquid phase capacitance for hydrogen sulfide is provided which dampens the effect of fluctuations in hydrogen sulfide content in the gas stream, etc.

    专利号:US-5075339-A
    优先权日:1989-07-28
    标 题:Benzylketone phospholipase A2 inhibitors
    发明人:WILKERSON WENDELL W
    权利人:DU PONT MERCK PHARMA
    摘要:The invention relates to benzylketone phospholipase A2 inhibitors, pharmaceutical compositions containing them, and methods of treating phospholipase A2-mediated conditions in mammals by administration of a therapeutically effective amount of such a benzylketone phospholipase A2 inhibitor. These compounds are also intermediates in the synthesis of other PLA2 inhibitors.

    专利号:US-11518933-B2
    优先权日:2016-05-25
    标题:Precursor based method of synthesis and fabrication of hybrid lighting phosphors with high quantum efficiency, and significantly enhanced thermal and photostability
    发明人:LI JING; FANG YANG; LIU WEI
    权利人:UNIV RUTGERS
    摘要:Highly thermal and photo-stable inorganic-organic hybrid phosphor compounds, in which a copper (I) halide module is coordinated with a multi-dentate organic ligand. Also disclosed are semiconductor and light emitting devices comprising these materials, including light emitting diodes, and methods of preparing these materials and devices.

    专利号:US-4948813-A
    优先权日:1987-11-30
    标题 :Benzylketone phospholipase A2 inhibitors
    发明人:WILKERSON WENDELL W
    权利人:DU PONT
    摘要:The invention relates to benzylketone phospholipase A2 inhibitors, pharmaceutical compositions containing them, and methods of treating phospholipase A2-mediated conditions in mammals by administration of a therapeutically effective amount of such a benzylketone phospholipase A2 inhibitor. These compounds are also intermediates in the synthesis of other PLA2 inhibitors.

    专利号:CN-109134173-A
    优先权日:2018-09-14
    标 题:A simple method for the synthesis of heterocyclic aryl ketones

    专利号:CN-109647528-B
    优先权日:2017-10-10
    标题 :Catalysts for Synthesis of Alkyl Aromatic Aldehydes

    供应商参考报价(招募中)

    品牌试剂参考报价(招募中)

    📌 第三方产品分析报告

    ✅ COA系统入驻 | 共享模式

    主要参考文献


    1: Rajnák C, Titiš J, Moncol J, Mičová R, Boča R. Field-Induced Slow Magnetic Relaxation in a Mononuclear Manganese(II) Complex. Inorg Chem. 2019 Jan 22;58(2):991-994. doi: 10.1021/acs.inorgchem.8b02675. Epub 2019 Jan 9. 45(4):1514-24. doi: 10.1039/c5dt03667d. 44(22):10289-96. doi: 10.1039/c5dt00568j. 80(6):1047-55. doi: 10.1124/mol.111.074427. Epub 2011 Aug 29.
    5: Skyrianou KC, Perdih F, Turel I, Kessissoglou DP, Psomas G. Nickel-quinolones interaction: part 3--Nickel(II) complexes of the antibacterial drug flumequine. J Inorg Biochem. 2010 Jul;104(7):740-9. doi: 10.1016/j.jinorgbio.2010.03.007. Epub 2010 Mar 24. 111(14):2715-21. doi: 10.1021/jp066031j. Epub 2007 Mar 22. 150(7):932-42. doi: 10.1038/sj.bjp.0707173. Epub 2007 Feb 26.
    8: Lotter M, Schilling J, Reimann E, Bracher F. First total synthesis of the 2,7-naphthyridine alkaloids lophocladine a and B. Arch Pharm (Weinheim). 2006 Dec;339(12):677-9. doi: 10.1002/ardp.200600134. 45(2):828-36. doi: 10.1021/ic051471v.

    合成参考文献


    摘要:Baudoin, O., Science of Synthesis: Catalytic Transformations via CH Activation, (2014) 2, 59.
    摘要:Yoshida, T.; Tobisu, M., Science of Synthesis: Special Topics, (2022) 1, 606.
    摘要:National Technical Information Service., OTS0570988
    摘要:U.S. Army Armament Research & Development Command, Chemical Systems Laboratory, NIOSH Exchange Chemicals., NX#12240
    摘要:Schafer, E.W. 1972. The acute oral toxicity of 369 pesticidal, pharmaceutical and other chemicals to wild birds. Toxicology and Applied Pharmacology. 21:315-330. https://www.aphis.usda.gov/ws/nwrc/chem-effects-db/A_Schafer_ToxicolApplPharmacol1972.pdf
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