CAS: 1197-21-3; Phentermine Hydrochloride

上下游产品

N-(2-methyl-1-phenylpropan-2-yl)acetamide 22H24NOPC22H24NOP 2-azido-2-methyl-3-phenylpropane benzyl bromide4-methyl-N-(2-methyl-1-phenylpropan-2-yl)benzenesulfonamide N-(2-methyl-1-phenylpropan-2-yl)-1-phenylmethanimine benzyl-(1,1-dimethyl-2-phenyl-ethyl)-amine (1,1-dimethyl-2-phenyl-ethyl)-(4-methoxy-benzyl)-amine

N-(Benzhydrylideneamino)-2-Methyl-1-Phenylpropan-2-Amine置于palladium On Activated Charcoal 盐酸,氢气体系中,用 乙醇 用作溶剂,50.0 °C,101.32 Kpa 条件下,反应生成盐酸苯丁胺
参考文献:合成中的偶氮阴离子:叔丁基二苯基甲基hydr的α-氨基碳负当量
标题:合成中的偶氮阴离子:叔丁基二苯基甲基hydr的α-氨基碳负当量
摘要:从叔丁基二苯基甲基hydr的c-烷基化产物可容易地获得α-氨基碳负当量(nh 2)和α-肼基阴离子当量(nhnh 2).这些偶氮烷可以在温和的反应条件下有效地转化为胺,肼和烷烃.
Doi:10.1039/c39860000176

专利信息

专利号:US-2006030625-A1
优先权日:2004-08-06
标 题 :Dietary neurotransmitter precursors for balanced synthesis of neurotransmitters
发明人：HART CHERYLE RAM; GROSSMAN RONALD S; RAM HERBERT
权利人:HART CHERYLE RAM; GROSSMAN RONALD S; RAM HERBERT
摘要:Dietary supplements for treating a neurotransmitter deficiency include one or more precursors of the deficient neurotransmitter and a cofactor for activating in vivo enzymatic synthesis of the deficient neurotransmitter. The dietary supplements can also include an appropriate neurotransmitter, such as an amino acid. When administered through the oral mucosa, increases in levels of the deficient neurotransmitters and relief from deficiency symptoms are obtained.

专利号:US-8529951-B1
优先权日:2007-02-21
标 题 :Elastogenic cues and methods for using same
发明人：RAMAMURTHI ANAND; KOTHAPALLI CHANDRASEKHAR; JODDAR BINATA
权利人:RAMAMURTHI ANAND; KOTHAPALLI CHANDRASEKHAR; JODDAR BINATA
摘要:Disclosed are elastogenic cues that can be utilized to encourage growth and development of elastin-containing cellular constructs. The elastogenic cues include hyaluronan fragments and oligomers, optionally in conjunction with growth factors and/or a source of copper ions. The elastogenic cues can up-regulate elastin matrix synthesis and by vascular smooth muscle cells. In addition to encouraging synthesis of elastin in a cellular matrix and organization into elastic fibers, the elastogenic cues can also stabilize the formed ECM matrix through suppression of elastin-laminin receptor (ELR). In addition, the elastogenic cues can inhibit cell hyper-proliferation (e.g., hyperplasia) common in inflammatory vascular disease.

专利号:US-7354923-B2
优先权日:2001-08-10
标 题 :Piperazine melanocortin-specific compounds
发明人：SHARMA SHUBH D; SHI YI-QUN; WU ZHIJUN; RAJPUROHIT RAMESH
权利人:PALATIN TECHNOLOGIES INC
摘要:Melanocortin receptor-specific piperazine or ketopiperazine compounds having the structure: n nand stereoisomer and pharmaceutically acceptable salts thereof, where X is CH 2 or Câ• O, R 1 , R 2 , and R 3 are as described in the specification, preferably where R 3 is a D-amino acid with at least one substituted or unsubstituted phenyl or naphthyl aromatic ring, and where R 3 optionally further includes an amine capping group, a second amino acid residue or a second amino acid residue with an amine capping group, which compounds are agonists, antagonists or mixed agonists and antagonists at one or more melanocortin receptors, and having utility in the treatment of melanocortin receptor-related disorders and conditions. Methods of synthesis of compounds of structure (I), pharmaceutical compositions containing a compound of structure (I) and methods relating to the use thereof are also disclosed.

专利号:WO-2005102340-A1
优先权日:2003-05-30
标题 :Piperazine melanocortin-specific compounds
发明人：SHARMA SHUBH D; SHI YI-QUN; WU ZHIJUN; RAJPUROHIT RAMESH
权利人:PALATIN TECHNOLOGIES INC; SHARMA SHUBH D; SHI YI-QUN; WU ZHIJUN; RAJPUROHIT RAMESH
摘要:Melanocortin receptor-specific piperazine or ketopiperazine compounds having the structure (I); and stereoisomer and pharmaceutically acceptable salts thereof, where X is CH2 or C=O, R1, R2, and R3 are as described in the specification, preferably where R3 is a D-amino acid with at least one substituted or unsubstituted phenyl or naphthyl aromatic ring, and where R3 optionally further includes an amine capping group, a second amino acid residue or a second amino acid residue with an amine capping group, which compounds are agonists, antagonists or mixed agonists and antagonists at one or more melanocortin receptors, and having utility in the treatment of melanocortin receptor-related disorders and conditions. Methods of synthesis of compounds of structure (I), pharmaceutical compositions containing a compound of structure (I) and methods relating to the use thereof are also disclosed.

专利号:US-11529298-B2
优先权日:2019-08-28
标题:Cosmetic composition and its use, dermocosmetic formulation
发明人：CARDOSO DE LIMA ERINE; BEZERRA TALITHA FARINA; FELIPE DE OLIVEIRA STEHLING LUIZ; MASIERO SILVANA
权利人:LUXBIOTECH FARM LTDA
摘要:The present invention relates to dermocosmetic formulations for use in combating skin aging, especially photoaging. The present invention promotes the increase of the synthesis of collagen, elastin and glycosaminoglycans (GAG), in addition to significantly increase the activity of the superoxide dismutase enzyme (SOD) and the cell proliferation.

专利号:US-8927485-B2
优先权日:2010-02-18
标题:Site-specific modification of proteins through chemical modification enabling protein conjugates, protein dimer formation, and stapled peptides
发明人：KRANTZ ALEXANDER; YU PENG
权利人:KRANTZ ALEXANDER; YU PENG; ADVANCED PROTEOME THERAPEUTICS INC
摘要:The present invention generally provides methods for the site-specific modification of peptides, polypeptides, and proteins, e.g., granulocyte macrophage colony-stimulating factor, human superoxide dismutase, annexin, leptin, antibodies and the like, cytokines and chemokines, at their N-termini and at sites at which unnatural aminoacids have been introduced along the protein framework. The modifications described herein can be used for the synthesis and application of the adducts in radio-labeling, molecular imaging and protein therapeutic applications, and the treatment of disorders such as rheumatoid arthritis, lupus erythematosus, psoriasis, multiple sclerosis, type-1 diabetes, Crohn's disease, and systemic sclerosis, Alzheimer disease, cancer, liver disease (e.g., alcoholic liver disease), and cachexia.