CAS: 60976-49-0; (57R,58S,510R,511R,519S)-14,15,16,24,25,26,52,53,516,517,517-Undecahydroxy-55,513,515,3,8-Pentaoxo-55,57,58,510,511,513,515,516,517,517A-Decahydro-4,7-Dioxa-5(19,10)-1,16-Epoxy-7,11-Methanodibenzo[i,K][1,4,7]Trioxacyclotridecina-1,2(1,2)-Dibenzenacyclooct

该化合物是一种天然产生的多酚化合物,主要存在于各种植物中,特别是在Geraniaceae家族中.它因其潜在的健康惠益而得到承认,包括抗氧化剂,抗炎和抗微生物特性.Geraniin是一种类型的lilagitanin,它来自对低酸和葡萄糖的凝结,它经常因其在传统医学中的作用及其在营养和药品中的潜在应用而受到研究.Geraniin表现出有机溶剂的溶解性,并且具有相对复杂的结构,有助于其生物活动.它的化学特性包括能够形成金属离子复合体并与各种生物巨型球相互作用,使其成为医药化学和天然产品研究的一个主题.此外,目前正在进行的研究正在探讨它对各种健康状况的影响,包括癌症和代谢紊乱,突出其在自然产品化学领域的重要性.

英文名称(57R,58S,510R,511R,519S)-14,15,16,24,25,26,52,53,516,517,517-Undecahydroxy-55,513,515,3,8-Pentaoxo-55,57,58,510,511,513,515,516,517,517A-Decahydro-4,7-Dioxa-5(19,10)-1,16-Epoxy-7,11-Methanodibenzo[i,K][1,4,7]Trioxacyclotridecina-1,2(1,2)-Dibenzenacyclooct
中文名称老鹳草素
IUPAC名称(57R,58S,510R,511R,519S)-14,15,16,24,25,26,52,53,516,517,517-undecahydroxy-55,513,515,3,8-pentaoxo-55,57,58,510,511,513,515,516,517,517a-decahydro-4,7-dioxa-5(19,10)-1,16-epoxy-7,11-methanodibenzo[i,k][1,4,7]trioxacyclotridecina-1,2(1,2)-dibenzenacyclooctaphane-58-yl 3,4,5-trihydroxybenzoate
其它别名Eraniin; Geraniin; B-D-Glucopyranose; Beta-D-Glucopyranose Cyclic 2-7:4-5-(3,6-Dihydro-2,9,10,11,11-Pentahydroxy-3-Oxo-2,6-Methano-2H-1-Benzoxocin-5,7-Dicarboxylate) Cyclic 3,6-(4,4',5,5',6,6'-Hexahydroxy[1,1'-Biphenyl]-2,2'-Dicarboxylate) 1-(3,4,5-Trihydroxybenzoate) Stereoisomer; 3,4,4,6,7,15,16,17,18,19,20-Undecahydroxy-2,9,13,22,27-Pentaoxo-2,3,4,4A,9,11A,13,22,24,25,25A,27-Dodecahydro-11H-3,5-Epoxy-25,11-(Epoxymethano)Dibenzo[h,J]Dibenzo[7,8:9,10][1,5]Dioxacycloundecino[3,2-B][1,6]Dioxacyclododecin-29-Yl 3,4,5-Trihydroxybenzoat; 5-(3,6-Dihydro-2,9,10,11,11-Pentahydroxy-3-Oxo-2,6-Methano-2H-1-Benzoxocin-5,7-Dicarboxylate)Cyclic 3,6-(4,4',5,5',6,6'-Hexahydroxy[1,1'-Biphenyl]-2,2'-Dicarboxylate)1-(3,4,5-Trihydroxybenzoate), Stereoisomer; 7:4®b-D-Glucopyranose, Cyclic 2®
CAS编号60976-49-0
MFCD编号:MFCD09038731
分子式:C41H28O27分子量:952.65
产品CID: 1590818
产品分类天然产物 → 酚类

相似结构搜索
产品信息参考;;;
InChIKey: JQQBXPCJFAKSPG-UHFFFAOYNA-N
JQQBXPCJFAKSPG-JAEVIPNINA-N
计算化学: 氢键受体数27.0氢键供体数14.0可旋转键数3.0

物理性质

密度2.3±0.1 g/cm3
pKa:6.35±0.70(预测)
PSA:450.25
LogP:3.41
折射率1.948
溶解性DMSO: 100 mg/mL (104.97 Mm; Need Ultrasonic)
外观形态淡黄色粉末
储存条件在惰性气体(氮气或氩气)下 2–8 °C
产品应用该化合物用作内容确定,识别和药理实验.

上下游产品

合成工艺路线路线简述

专利信息

专利号:US-7829124-B2
优先权日:2001-04-26
标题:Use of Phyllanthus constituents for treating or preventing infections caused by hepatitis B-viruses
发明人：OTT MICHAEL; MANNS MICHAEL P
权利人:OTT MICHAEL; MANNS MICHAEL P
摘要:The disclosure relates to a method of inhibiting synthesis of viral DNA in a mammal infected with a hepatitis B virus. This method includes administering at least one Phyllanthus component or substance to a mammal infected with the hepatitis B virus. It also includes inhibiting hepatitis B viral DNA synthesis in the mammal using the Phyllanthus component or substance. The disclosure also relates to a method of inhibiting viral gene expression in a mammal infected with a hepatitis B virus. This method includes administering at least one Phyllanthus component or substance to a mammal infected with the hepatitis B virus. It also includes inhibiting expression of at least one hepatitis B viral gene in the mammal using the Phyllanthus component or substance. These methods may form part of a method of preventing or treating hepatitis B infection.

专利号:JP-2012121858-A
优先权日:2010-12-10
标题:A method for extracting and purifying active ingredients in geno shochu efficiently and with high purity, and creation of DPPH radical scavengers, SOD activity-like agents, melanin synthesis inhibitors, fading inhibitors, and enzyme inhibitors using the active ingredients

其他信息查阅

供应商参考报价(招募中)

品牌试剂参考报价(招募中)

实用工具

📌 第三方产品分析报告

✅ COA系统入驻 | 共享模式

合成参考文献

参考文献:10.1248/bpb.31.743
摘要:Li J, Huang H, Zhou W, Feng M, Zhou P. Anti-hepatitis B Virus Activities of Geranium carolinianum L. Extracts and Identification of the Active Components. Biological & Pharmaceutical Bulletin. 2008;31(4):743–7. doi: 10.1248/bpb.31.743.