CAS: 5331-91-9; 5-Chlorobenzo[d]Thiazole-2(3H)-Thione

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CAS号95-82-9 2,5-二氯苯胺 | CAS号140-89-6 乙基黄原酸钾 | CAS号75-15-0 二硫化碳 | CAS号1004-00-8 2-氨基-4-氯苯硫醇 | CAS号3507-41-3 5-氯-2-(甲硫基)苯并噻唑 | CAS号20174-72-5 2(3H)-Benzothia... | CAS号2786-51-8 5-氯苯并噻唑 | CAS号20600-44-6 5-氯-2-苯骈噻唑酮 | CAS号2941-48-2 2,5-二氯苯并噻唑 | CAS号74537-45-4 2-(5-CHLOROBENZ... | CAS号85750-08-9 ethyl 5-chloro-... | CAS号90660-75-6 2-[(5-chloro-1,... | CAS号92064-61-4 3-[(5-chloro-1,... | CAS号110672-07-6 5-chloro-2-thio...

📜5-氯苯并噻唑置于1,3-丙二硫醇,二甲基亚砜,Potassium Hydroxide体系中,化学反应 12.0H,以74%的收率获得产物2-巯基-5-氯苯并噻唑
参考文献:Metal-Free C-h Mercaptalization Of Benzothiazoles And Benzoxazoles Using 1,3-Propanedithiol As Thiol Source
标题:Metal-Free C-h Mercaptalization Of Benzothiazoles And Benzoxazoles Using 1,3-Propanedithiol As Thiol Source
摘要:描述了一种简便有效的c-H官能化策略,用于合成2-巯基苯并噻唑和2-巯基苯并噁唑.在氢氧化钾和二甲基亚砜存在下,采用1,3-丙二硫醇将苯并噻唑和苯并噁唑转化为相应的杂环硫醇.这种新颖的方案以对杂环烃的直接c-H巯基化和简单的反应体系为特点.
DOI:10.3762/bjoc.15.24

专利信息

专利号:US-6531470-B1
优先权日:1998-01-23
标题:Oxazolidinone combinatorial libraries, compositions and methods of preparation
发明人：GORDEEV MIKHAIL F; LUEHR GARY W; PATEL DINESH V; NI ZHI-JIE; GORDON ERIC
权利人:UPJOHN CO
摘要:Oxazolidinones and methods for their synthesis are provided. Also provided are combinatorial libraries comprising oxazolidinones, and methods to prepare the libraries. Further provided are methods of making biologically active oxazolidinones as well as pharmaceutically acceptable compositions comprising the oxazolidinones. The methods of library preparation include the attachment of oxazolidinones to a solid support. The methods of compound preparation in one embodiment involve the reaction of an iminophosphorane with a carbonyl containing polymeric support.

专利号:US-6562844-B2
优先权日:1998-01-23
标 题:Oxazolidinone combinatorial libraries, compositions and methods of preparation
发明人：GORDEEV MIKHAIL F; LUEHR GARY W; PATEL DINESH V; NI ZHI-JIE; GORDON ERIC
权利人:UPJOHN CO
摘要:Oxazolidinones and methods for their synthesis are provided. Also provided are combinatorial libraries comprising oxazolidinones, and methods to prepare the libraries. Further provided are methods of making biologically active oxazolidinones as well as pharmaceutically acceptable compositions comprising the oxazolidinones. The methods of library preparation include the attachment of oxazolidinones to a solid support. The methods of compound preparation in one embodiment involve the reaction of an iminophosphorane with a carbonyl containing polymeric support.

专利号:US-5215987-A
优先权日:1990-04-23
标题:Substituted benzhydryl 2-hydroxypropyl piperazine derivatives
发明人：HAJOS ZOLTAN G; KANOJIA RAMESH M; PRESS JEFFREY B
权利人:ORTHO PHARMA CORP
摘要:Substituted benzhydryl 2-hydroxypropyl piperazine derivatives and methods of synthesis of the derivatives are described. The substituted benzhydryl 2-hydroxypropyl piperazine derivatives are useful as cardiotonic agents.

专利号:US-7002020-B1
优先权日:1998-01-23
标题:Oxazolidinone combinatorial libraries, compositions and methods of preparation
发明人：GORDEEV MIKHAIL F; LUEHR GARY W; PATEL DINESH V
权利人:UPJOHN CO
摘要:Oxazolidinones and methods for their synthesis are provided. Also provided are combinatorial libraries comprising oxazolidinones, and methods to prepare the libraries. Further provided are methods of making biologically active oxazolidinones as well as pharmaceutically acceptable compositions comprising the oxazolidinones. The methods of library preparation include the attachment of oxazolidinones to a solid support. The methods of compound preparation in one embodiment involve the reaction of an iminophosphorane with a carbonyl containing polymeric support.

专利号:CN-118812458-A
优先权日:2024-07-02
标 题 :Synthesis method of 2-mercaptobenzothiazole derivatives

专利号:CN-1789253-A
优先权日:2005-12-28
标题:Synthesis and fungicidal activity of a class of benzothiazole derivatives