CAS: 3609-87-8; N-Benzyl-4-Bromobenzenesulfonamide
该化合物是一种有机化合物,其特征是其磺酰胺功能组,该功能组附属于一个苯环,该苯环又被一个溴原子和苯基组所取代;该化合物一般在室温时是一种固体,因其在药用化学中的潜在应用而闻名,特别是因其与生物目标相互作用的能力而在药物研制过程中的潜在应用;溴原子的存在增强了其反应性,并可能影响其生物活动;全氟辛烷磺酸组有助于其在极溶剂中的溶解性,而苯基混合物可提供亲脂性,影响其药用皮肤特性;此外,N-苯基-4-溴苯基苯基磺酰胺可能具有抗菌性或抗炎特性,使其在药物设计中具有兴趣;应当就处理和接触问题参考安全数据,如同任何化学物质一样,以确保遵循适当的实验室做法.
- 英文名称N-Benzyl-4-Bromobenzenesulfonamide
- 中文名称N-苄基-4-溴苯磺酰胺
- IUPAC名称N-benzyl-4-bromobenzenesulfonamide
- 其它别名N-Benzyl 4-Bromobenzenesulfonamide; N-Benzyl-4-Bromobenzenesulphonamide; N-Benzyl-4-Bromobenzenesulphonamide ; N-Benzyl-4-Bromobenzenesulphonamide; Benzenesulfonamide, 4-Bromo-N-(Phenylmethyl)-; ν-Benzyl-4-Bromobenzenesulfonamide; N-Benzyl 4-Bromobenzenesulfonamide Usp/ep/bp
- CAS编号3609-87-8
- MFCD编号:MFCD00450587
- 分子式:C13H12BrNO2S分子量:326.21
- 产品CID: 1370012
- 产品分类有机原料→分子砌块→芳环类化合物→苯类化合物
物理性质
MSDS等安全信息
上下游产品
CAS号100-46-9 苄胺 | CAS号98-58-8 对溴苯磺酰氯 | CAS号701-34-8 4-溴苯磺酰胺 | CAS号100-51-6 苯甲醇合成工艺路线路线简述
- 合成目标产物 N-Benzyl 4-Bromobenzenesulfonamide 主要起始原料 Benzylamine And 4-Bromobenzenesulfonyl Chloride
- (文献来源)合成步骤主要原料 Benzylamine 和 4-Bromobenzenesulfonyl Chloride
📜4-溴苯磺酰胺置于四氢吡咯,甲醇,Potassium Tert-Butylate,联硼酸频那醇酯,Copper(L) Chloride体系中,用 四氢呋喃,二氯甲烷 作为反应溶剂,化学反应 12.0H,反应生成 N-苄基-4-溴苯磺酰胺
参考文献:Copper-Boryl Mediated Transfer Hydrogenation Of N-Sulfonyl Imines Using Methanol As The Hydrogen Donor
标题:Copper-Boryl Mediated Transfer Hydrogenation Of N-Sulfonyl Imines Using Methanol As The Hydrogen Donor
摘要:
DOI:10.1016/j.Tet.2021.132063
海关参考信息
- 2902300000-甲苯
- 💡 提示：海关信息按照顺序优先匹配，如需确认的海关信息，请参考相关资料。
- 详情请参考：📖 海关编码查询和海关进出口税则
专利信息
专利号:WO-2004020401-A1
优先权日:2002-09-02
标题 :Synthesis of sulfonamide derivatives
发明人：KALLIKAT JOHN; MANDAL ASHIS BARAN; GANESH SAMBASIVAM
权利人:SYNGENE INTERNAT PRIVATE LTD; KALLIKAT JOHN; MANDAL ASHIS BARAN; GANESH SAMBASIVAM
摘要:The novel method of synthesis of sulphonamide derivatives (I), comprising reaction of alkyl-4-halophenylsulfonate with an amine. Formula (I) wherein X is halogen and R1 and R2 are independently selected from group comprising (i) C1 to C15 alkyl, straight or branched, (ii) C3 to C15 cycloalkyl, substituted or unsubstituted, (iii) C2 to C15 alkenyl, straight or branched, (iv) C2 to C15 alkynyl, straight or branched, (v) phenyl or benzyl, substituted or unsubstituted, (vi) heterocycloalkyl, substituted or unsubstituted, (vii) hydrogen, (viii) form with the nitrogen to which they are attached a 3-7 membered heterocyclic moiety such as pyrolidine, piperidine, piperazine, imidazole, pyrazole, (ix) the alkyl in i) may be attached to a moiety selected from cycloalkyl or heterocycloalkyl, substituted or unsubstituted
专利号:CN-118344268-A
优先权日:2024-04-18
标 题:Synthesis method of N-alkyl sulfonamide
供应商参考报价(招募中)
品牌试剂参考报价(招募中)
📌 第三方产品分析报告
合成参考文献
参考文献:10.1055/s-0029-1217891
摘要:Alkylation of Sulfonamides with Alcohols. Synfacts. 2009 Sep 22;2009(10):1138. doi: 10.1055/s-0029-1217891.
📝 需求与反馈
尽可能描述清楚需求与问题信息
