专利号:US-2010055187-A1 优先权日:2008-08-28 标题:Nanovitamin synthesis 发明人:AHN DONG JUNE 权利人:AHN DONG JUNE 摘要:Stable nanoparticulate vitamin compositions are prepared from agglomerated or larger sized vitamin particles of at least one vitamin compound by breaking down and/or solubilizing the agglomerated or larger sized vitamin particles and associating the particles with a surface modifying agent.
专利号:US-7427690-B2 优先权日:2004-06-05 标 题 :Multifunction “crown complexesâ€? from amino acids and peptides for skin and hair restoration 发明人:GUPTA SHYAM K 权利人:BIODERM RESEARCH 摘要:This invention relates to Schiff's bases derived from amino acids and hydroxyaryl alkyl ketones, or a plant extract containing the same, having general chemical structure in FIG. 1 for topical application. This invention also relates to certain metal complex of said Schiff's bases, which have a crown-like appearance in their three-dimensional chemical structure, as in FIG. 2 . The Schiff's bases and their metal complexes of the present invention are useful for the modulation of metal-activated enzymes and metalloenzymes, such as Phenylalanine Hydroxylase, Tyrosine Transaminase, Phenylalanine Transaminase, Tyrosinase, various MMP (Matrix metalloproteases), Superoxide dismutase, 5-Alpha Reductase, and citrate lyase. These are further suitable for multifunctional topical methods for skin whitening, skin wrinkles reduction, skin antiaging, collagen synthesis, acne control, hair loss prevention, hair graying control, and facial oil control.
1: Prieto-Blanco MC, Moliner-Martínez Y, López-Mahía P, Campíns-Falcó P. Ion-pair in-tube solid-phase microextraction and capillary liquid chromatography using a titania-based column: application to the specific lauralkonium chloride determination in water. J Chromatogr A. 2012 Jul 27;1248:55-9. doi: 10.1016/j.chroma.2012.05.099. Epub 2012 Jun 7.