CAS: 85201-91-8; Z-Hyp(Tbu)-Oh

化学文摘社编号为85201-91-8,是一个独特的识别标志,有助于在化学数据库中识别和采购该化合物.与许多有机化合物一样,处理应谨慎,遵循适当的安全协议,以减少与使用该化合物有关的任何风险.

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上下游产品

CAS号112203-99-3 Z-Hyp(OH)-ONB | CAS号13504-85-3 CBZ-L-羟脯氨酸

合成工艺路线路线简述

  • 146951-99-7 = 85201-91-8
    反应条件:1.1 Reagents: Lithium Hydroxide Solvents: Tetrahydrofuran,Water; 6 H,Rt
    标题:A Fluorous Proline Catalyst Immobilized On Teflon For Highly Stereoselective Asymmetric Aldol Reactions
    作者:Ishihara,Kazuki; Obayashi,Riho; Ohira,Mizuki; Kobayashi,Yuki; Ishihara,Kotaro; Et Al
    参考文献:Heterocycles 日期:2021 卷标:103(2) 页码:839-861]

    117106-23-7 = 85201-91-8
    反应条件:1.1 Reagents: Sodium Hydroxide Solvents: Acetone,Water
    标题:Synthesis Of Linear Undecapeptide Precursors Of Cyclosporin Analogs
    作者:Galpin,I. J.; Mohammed,A. K. A.; Patel,A.
    参考文献:Tetrahedron 日期:1988 卷标:44(6) 页码:1773-82
📜Z-Hyp(Oh)-Onb置于sodium Hydroxide,硫酸体系中,用 二氯甲烷,丙酮 作为反应溶剂,化学反应 122.5H,反应生成 (4R)-(叔丁氧基)-1-(苯甲氧羰基)-L-脯氨酸
参考文献:Synthesis Of Linear Unidecapeptide Precursors Of Cyclosporin Analogues
标题:Synthesis Of Linear Unidecapeptide Precursors Of Cyclosporin Analogues
摘要:
DOI:10.1016/s0040-4020(01)86742-9

海关参考信息

专利信息


专利号:US-2004110228-A1
优先权日:2002-04-01
标 题:Combinatorial organic synthesis of unique biologically active compounds
发明人:MCALPINE SHELLI R; TAYLOR RACHEL E; BOLLA MEGAN L; SEGALL ANCA M
摘要:The invention provides a method for making a combinatorial library of cyclic compounds, such as Holliday junction-trapping compounds, comprising the steps of (a) obtaining a plurality of trimers according to the generic structure X 1- X 2- X 3 , wherein X 1 , X 2 and X 3 can be independently any naturally or nonnaturally occurring amino acids or peptidomimetics thereof; (b) optionally coupling a spacer S to the trimer at either end; (c) cyclizing two trimers or trimer-spacer conjugates in a head-to-tail orientation; thereby obtaining a combinatorial library of compounds, wherein the library does not include an unmodifed or naturally occurring Holliday Junction-trapping compounds. The invention additionally provides methods macrocyclic compounds that are synergimycin derivatives.

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合成参考文献

合成方法参考DOI号:10.1016/S0040-4020(01)86742-9
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