CAS: 7335-27-5; Ethyl 4-Chlorobenzoate

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CAS号64-17-5 乙醇 | CAS号104-88-1 对氯苯甲醛 | CAS号74-11-3 对氯苯甲酸 | CAS号106-39-8 对氯溴苯 | CAS号109-94-4 甲酸乙酯 | CAS号637-87-6 对氯碘苯 | CAS号1906-57-6 乙基草酸钾 | CAS号2403-61-4 4-氯代苯甲醛缩二乙醇 | CAS号201230-82-2 carbon monoxide | CAS号74-96-4 溴乙烷 | CAS号10129-07-4 4-苯基磺酰基-苯甲酸乙酯 | CAS号882-33-7 二苯二硫醚 | CAS号1262675-57-9 ethyl 4-(acetyl... | CAS号538-58-9 二亚苄叉丙酮DBA | CAS号49742-56-5 4’-甲基[1,1’-联苯]-... | CAS号47230-38-6 4,4'-联苯二甲酸二乙酯 | CAS号261516-38-5 (4-(ethoxycarbo... | CAS号93-89-0 苯甲酸乙酯 | CAS号583-02-8 4-(三氟甲基)苯甲酸乙酯 | CAS号50677-27-5 4-氯-N'-(2-氯乙酰基)苯甲酰肼

4-氯-N-异丙基苯甲酰胺置于盐酸,Disodium Hydrogenphosphate体系中,用 二氯甲烷,水 作为反应溶剂,化学反应 96.0H,反应生成 4-氯苯甲酸乙酯
参考文献:The Conversion Of Amides To Esters With Meerwein'S Reagent. Application To The Synthesis Of A Carfentanil Precursor.
标题:The Conversion Of Amides To Esters With Meerwein'S Reagent. Application To The Synthesis Of A Carfentanil Precursor.
摘要:An Efficient Two Step Transformation Of 1 Degrees And 2 Degrees Amides To Methyl And Ethyl Esters Has Been Developed Using Trimethyl-And Triethyloxonium Tetrafluoroborates,And Dilute Acid. This Methodology Was Applied To 1-Benzyl-4-Phenylamino-4-Piperidinecarboxamide Precursor In The Synthesis Of Carfentanil,To Produce The Methyl Ester In 60% Yield And The Ethyl Ester In 80% Yield.
DOI:10.1080/00397919708004212

专利信息

专利号:WO-2021225823-A1
优先权日:2020-05-06
标 题:Synthesis of vinylic protected alcohol intermediates

专利号:CN-112300020-A
优先权日:2019-11-28
标题:A kind of method for vanadium-catalyzed synthesis of amide derivatives

专利号:WO-2023231948-A1
优先权日:2022-05-30
标 题:Isr inhibitors, method for preparing same, and use thereof
发明人：ZHANG HUIBIN; ZHOU JINPEI; WANG LIXUN; PEI YIFENG
权利人:UNIV CHINA PHARMA
摘要:Disclosed are a class of ISR inhibitors, a method for preparing same, and use thereof. The present invention belongs to the technical field of biopharmaceutics. The compound of the present invention is a compound having a structure of formula (I) or formula (II), a stereoisomer thereof, a geometric isomer thereof, a tautomer thereof, a pharmaceutically acceptable salt thereof, a prodrug thereof, a hydrate thereof or a solvate thereof. The compound provided by the present invention can effectively bind to elF2B, has a good ability to inhibit ATF4, and can well restore protein synthesis upon ISR stimulation. Therefore, the compound of the present invention can be used as an ISR inhibitor for treating various related diseases.

专利号:CN-112300020-B
优先权日:2019-11-28
标题:A kind of method of vanadium catalysis synthesis amide derivative

专利号:CN-116813475-A
优先权日:2022-06-29
标题 :A kind of halogenation synthesis method of aromatic ring compounds

专利号:CN-118791394-A
优先权日:2024-07-18
标 题:Synthesis method of alpha-amino acid ester compound